Review
Biotechnology & Applied Microbiology
Gaetano Giudice, Loredana Moffa, Serena Varotto, Maria Francesca Cardone, Carlo Bergamini, Gabriella De Lorenzis, Riccardo Velasco, Luca Nerva, Walter Chitarra
Summary: This review focuses on challenging biotechnological approaches for breeding crops tolerant to biotic and abiotic stresses, as well as new techniques based on RNA interference and epigenome modifications to improve plant resilience. Recent advances in these applications are mainly reported for non-model plants and woody crops, and their combination with traditional breeding is discussed as a potential contribution to modern agriculture and climate change mitigation.
PLANT BIOTECHNOLOGY JOURNAL
(2021)
Review
Biochemical Research Methods
David A. Brummell, Joanna K. Bowen, Nigel E. Gapper
Summary: Fruit softening is a crucial factor in determining the postharvest life and quality of fruits, and it can be controlled by regulating the cell wall, cuticle, and soluble sugars. Research on genes involved in cell wall and cuticle properties, as well as the silencing of multiple genes by targeting single transcription factors, offers promising targets for biotechnology.
CURRENT OPINION IN BIOTECHNOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Cedric Schirmer, Rudiger W. Maschke, Ralf Portner, Dieter Eibl
Summary: This review provides an overview of the most common agitation and seal types implemented in stirred bioreactor systems, focusing on their advantages and disadvantages, and explaining their possible fields of application. Special attention is paid to the development of magnetically driven agitators, which are widely used and becoming more important in both reusable and single-use systems.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Manoj Koirala, Vahid Karimzadegan, Nuwan Sameera Liyanage, Natacha Merindol, Isabel Desgagne-Penix
Summary: Amaryllidaceae alkaloids (AAs) are therapeutic plant metabolites exclusively produced by the Amaryllidaceae plant family. The production variability of AAs in plants hinders their pharmaceutical applications. Biotechnological approaches such as in vitro culture and synthetic biology are being developed to enhance the production of these plant-derived drugs.
Article
Energy & Fuels
Jiao Xue, Srinivasan Balamurugan, Tong Li, Jia-Xi Cai, Ting-Ting Chen, Xiang Wang, Wei-Dong Yang, Hong-Ye Li
Summary: The review discusses the potential of metabolic engineering strategies to enhance lipid accumulation in microalgae for biofuel production. It emphasizes the importance of designing appropriate strategies for scale-up processes and utilizing advancements in DNA manipulation techniques. Additionally, the review highlights the need for streamlining engineering strategies to overcome biological complexities in lipogenesis.
Review
Plant Sciences
Haiyue Gong, Ping He, Xiaozhong Lan, Lingjiang Zeng, Zhihua Liao
Summary: In this review, we summarize the advances in the biosynthesis and engineering of MTA production, which holds great significance for the pharmaceutical industry.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Biochemical Research Methods
Nigel E. Gapper, Joanna K. Bowen, David A. Brummell
Summary: Fruit storage disorders, such as chilling injury and respiratory injury, are a major cause of crop losses and downgrades. Biotechnological approaches are being used to better understand these processes and provide resistance/tolerance to them. Reducing postharvest crop losses through improved cultivars or inventory management is crucial for food security.
CURRENT OPINION IN BIOTECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Ramon Gonzalez, Andrea M. Guindal, Jordi Tronchoni, Pilar Morales
Summary: Global climate warming leads to an increase in sugar content in grapes and alcohol level in wines. Researchers are exploring biotechnological solutions such as genetic improvement to lower alcohol yields and develop commercial yeast strains with reduced ethanol production. The optimization of fermentation processes using natural isolates is expected to be the most probable source of advancement in the short term.
Review
Plant Sciences
Edgar Perez-Matas, Diego Hidalgo-Martinez, Ainoa Escrich, Miguel Angel Alcalde, Elisabeth Moyano, Mercedes Bonfill, Javier Palazon
Summary: Paclitaxel and its derivatives are widely used chemotherapeutic agents for cancer treatment, but their production remains challenging due to scarcity. This review discusses the progress in improving taxane production through genetic engineering techniques, including the overexpression of limiting genes and transcription factors in Taxus spp. cells and transformed roots, as well as attempts to produce taxanes in heterologous organisms. However, the transfer of the complete PTX metabolic route has not been achieved yet, and taxane biosynthesis is still restricted to Taxus cells and some endophytic fungi.
FRONTIERS IN PLANT SCIENCE
(2023)
Review
Pharmacology & Pharmacy
Fang-Fang He, Yu-Mei Wang, Yi-Yuan Chen, Wei Huang, Zi-Qi Li, Chun Zhang
Summary: Sepsis is a complex clinical syndrome caused by infectious or noninfectious factors. Acute kidney injury (AKI) is a common and severe complication of sepsis, and recent evidence suggests that autophagy and natural products may have therapeutic effects on sepsis-associated AKI.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Praveen C. Ramamurthy, Simranjeet Singh, Dhriti Kapoor, Parul Parihar, Jastin Samuel, Ram Prasad, Alok Kumar, Joginder Singh
Summary: The escalating energy demands due to the growing global population and industrialization have led to a significant energy crisis, requiring the exploration of alternative renewable fuels. The use of microorganisms to convert organic compounds into renewable energy fuels shows great promise in addressing environmental concerns and energy sustainability.
MICROBIAL CELL FACTORIES
(2021)
Review
Genetics & Heredity
Pritam Kumari, Poonam Jasrotia, Deepak Kumar, Prem Lal Kashyap, Satish Kumar, Chandra Nath Mishra, Sudheer Kumar, Gyanendra Pratap Singh
Summary: The cost of insect pest control in agriculture is high globally, and there is a need for alternative pest management strategies. Biotechnological approaches such as gene editing, transformation, and marker-assisted selection provide new opportunities for developing insect-resistant engineered crop genotypes, improving pest management.
FRONTIERS IN GENETICS
(2022)
Article
Green & Sustainable Science & Technology
Ashira Roopnarain, Haripriya Rama, Busiswa Ndaba, Maryam Bello-Akinosho, Emomotimi Bamuza-Pemu, Rasheed Adeleke
Summary: With the increasing global demand for green energy, anaerobic digestion has gained more research interest due to its dual benefits. However, a key challenge lies in the quality and quantity of the products, such as biogas and digestate, which can be addressed through process optimization. Collaboration between experts in microbiology and technological design is crucial for achieving this optimization and enhancing the overall performance of anaerobic digestion systems.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2021)
Review
Biochemical Research Methods
Joanna K. Bowen, David A. Brummell, Nigel E. Gapper
Summary: Understanding host immune responses and pathogen virulence enables the development of more sophisticated strategies for fruit disease control. Gene editing and RNA interference techniques provide more precise control options without generating genetically modified organisms or leaving traces of introduced genetic material.
CURRENT OPINION IN BIOTECHNOLOGY
(2022)
Review
Biochemical Research Methods
Gian Marco Luna, Grazia Marina Quero, Fotini Kokou, Konstantinos Kormas
Summary: The fish microbiome is crucial for the health of the fish and its interactions with the environment. Biotechnological applications, such as manipulation of microbial communities, in vitro gut simulators, and synthetic microbial communities, offer new prospects for studying and engineering the fish microbiome. This article summarizes the current knowledge and strategies for manipulating the fish microbiome to improve fish health, food safety, and environmental sustainability.
CURRENT OPINION IN BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Hosakatte Niranjana Murthy, Guggalada Govardhana Yadav, Sathish Shekhappa Kadapatti, M. Sandhya
Summary: The objective of this study was to evaluate the phytochemicals and antioxidant potential of Garcinia indica resin. Acetone and methanol extracts contain high amounts of phenolics and flavonoids, while methanol extract has the highest alkaloid content. GC-MS analysis identified terpenoids as the major compounds in acetone extract. Both acetone and methanol extracts showed excellent antioxidant activity. This study suggests that G. indica resin can be used for medicinal applications.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Review
Chemistry, Inorganic & Nuclear
Jissa Theresa Kurian, Preethy Chandran, Joseph Kadanthottu Sebastian
Summary: Considering the unique environmental conditions and geological characteristics, Indian flora is diverse and contains a wide array of medicinal plants. Plant parts and their metabolites have been extensively studied for their medicinal and culinary uses throughout history. The phytochemicals found in these plants have the potential to be used as reducing agents for the bio-fabrication of nanoparticles. This review focuses on the potential applications of inorganic nanoparticles synthesized from 148 traditionally used medicinal plants in India, and discusses the various parameters that influence their green synthesis.
JOURNAL OF CLUSTER SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee Yoeup Paek, So Young Park
Summary: This article introduces the major groups of medicinal plants in the Rubia genus, such as Rubia cordifolia, Rubia tinctorum, and Rubia akane. These plants contain anthraquinones (AQs), particularly alizarin and purpurin, which have various pharmacological effects. AQs have been used as natural dyes and color additives in industries. Different techniques and approaches, including cell and organ cultures, have been used to produce biomass and secondary metabolites from Rubia species. Bioreactor cultures have also been emphasized as a method to grow cells for AQ production.
Review
Infectious Diseases
Juhi Puthukulangara Jaison, Balamuralikrishnan Balasubramanian, Jaya Gangwar, Nilina James, Manikantan Pappuswamy, Arumugam Vijaya Anand, Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu, Wen-Chao Liu, Joseph Kadanthottu Sebastian
Summary: The Asteraceae family, with its rich phytochemicals, is widely used for traditional and medicinal purposes. These plants have found applications in various biological fields and nanotechnology. The synthesized nanoparticles from Asteraceae plants are stable, inexpensive, non-toxic, and eco-friendly, and have extensive applications in antibacterial, antifungal, antioxidant, anticancer, antidiabetic, and photocatalytic activities. This review provides an opportunity to understand the recent trend in green synthesis of advanced nanoparticles and discusses the extraction methods, synthesis, characterization, and potential applications of Asteraceae-mediated nanoparticles for human welfare. Constraints and future prospects for green synthesis of nanoparticles from Asteraceae family are summarized.
Article
Biology
Dayanand Dalawai, Hosakatte Niranjana Murthy, Yaser Hassan Dewir, Joseph Kadanthottu Sebastian, Anish Nag
Summary: This study determined the phytochemical composition and bioactive chemical components of Andrographis macrobotrys using GC-MS, and evaluated the antioxidant potential of its extracts. The results showed that the stem extract of the plant has a higher concentration of phenolics and exhibits strong antioxidant activity. These findings highlight the importance of A. macrobotrys as a medicinal plant and a potential source of antioxidants.
Article
Horticulture
Hosakatte Niranjana Murthy, Guggalada Govardhana Yadav, Sathish Shekhappa Kadapatti, Akarsha H. Pote, Ramalinga Jagali, Vidya Yarashi, Yaser Hassan Dewir
Summary: The present study investigated the nutritional composition, phytochemical composition, and antioxidant activities of Rourea minor fruits. The ripened seeds and pulp contained various components, including fat, protein, carbohydrates, ash, and fiber. Both the seeds and pulp were also rich in microelements. The study also found that the extracts from the fruits exhibited strong antioxidant activity. The findings suggest that Rourea minor fruits could be a valuable source of nutrients, microelements, and antioxidants.
Article
Horticulture
Yaser Hassan Dewir, Muhammad M. Habib, AbdulAziz A. AlQarawi, Thobayet S. Alshahrani, Ahmed Ali Alaizari, Jahangir A. Malik, Mona S. Alwahibi, Hosakatte Niranjana Murthy
Summary: This study examined the effect of arbuscular mycorrhizal fungi (AMF) on the growth and development of tissue-cultured Philodendron bipinnatifidum plantlets during the acclimatization phase. The results showed that AMF-treated plants had better growth characteristics and root development compared to non-AMF plants. These findings highlight the importance of mycorrhization in promoting vegetative growth and acclimatization of micropropagated plants.
Review
Biotechnology & Applied Microbiology
Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee Yoeup Paek, So Young Park
Summary: In vitro plant cell and organ cultures are attractive alternatives for producing valuable specialized metabolites. Adventitious roots are often superior to cell suspension cultures for accumulating high levels of specialized metabolites. Different bioreactor systems have been investigated for cultivation of adventitious roots.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jissa Theresa Kurian, Balamuralikrishnan Balasubramanian, Arun Meyyazhagan, Manikantan Pappuswamy, Amer M. Alanazi, Kannan RR. Rengasamy, Vijaya Anand Arumugam, Joseph Kadanthottu Sebastian, Jen-Tsung Chen
Summary: This study synthesized Ag NPs using a green method and evaluated their physical properties, antimicrobial, antioxidant, and anti-cancer properties, as well as photocatalytic ability. The results showed that the synthesized Ag NPs exhibited excellent photocatalytic activity and demonstrated promising applications in the biomedical field.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2023)
Review
Plant Sciences
Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee Yoeup Paek, So Young Park
Summary: Plant cells and organ cultures are viable alternatives for producing specialized metabolites. Elicitation is a strategy used to enhance the accumulation of these compounds, and nanoparticles have recently been used as unique elicitors. This review summarizes the applications and usage of nanoparticles as elicitors in plant cell and organ cultures.
PLANT GROWTH REGULATION
(2023)
Review
Plant Sciences
Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Jong-Eun Hahn, Han-Sol Lee, Kee Yoeup Paek, So Young Park
Summary: This review provides an update on the use of somatic embryogenesis in the production of valuable secondary metabolites, discussing the factors influencing their generation, elicitation methods, and prospective applications.
PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS
(2023)
Article
Business
V. Mamtha, H. N. Narasimha Murthy, V. Pujith Raj, Prashantha Tejas, C. S. Puneet, Achyutha Venugopal, Sham AanMankunipoyil, C. Manjunatha
Summary: This study investigates the synergistic effect of AgNP and MgO as nanofillers in electrospun Polyurethane. The results show that the addition of MgO improves the physical properties of the nanofibers, while the addition of AgNP enhances the antibacterial activity.
CLOTHING AND TEXTILES RESEARCH JOURNAL
(2023)
