CD28/PD1 co-expression: dual impact on CD8+ T cells in peripheral blood and tumor tissue, and its significance in NSCLC patients' survival and ICB response
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CD28/PD1 co-expression: dual impact on CD8+ T cells in peripheral blood and tumor tissue, and its significance in NSCLC patients' survival and ICB response
Authors
Keywords
-
Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 42, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-28
DOI
10.1186/s13046-023-02846-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
- (2023) Yunlong Zhao et al. IMMUNITY
- Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non–Small-Cell Lung Cancer
- (2023) Lissete Sánchez-Magraner et al. JOURNAL OF CLINICAL ONCOLOGY
- CTLA4 prohibits T cells from cross-dressing
- (2023) Noémie Paillon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An integrated single-cell transcriptomic dataset for non-small cell lung cancer
- (2023) Karolina Hanna Prazanowska et al. Scientific Data
- Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
- (2022) Karl L. Banta et al. IMMUNITY
- Heterogeneity of tissue resident memory T cells
- (2022) Špela Konjar et al. IMMUNOLOGY LETTERS
- ‘Stem-like’ precursors are the fount to sustain persistent CD8+ T cell responses
- (2022) Dietmar Zehn et al. NATURE IMMUNOLOGY
- Regulatory T‐cell development in the tumor microenvironment
- (2022) Kota Itahashi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
- (2021) Moran Yang et al. Journal for ImmunoTherapy of Cancer
- Circulating clonally expanded T cells reflect functions of tumor-infiltrating T cells
- (2021) Liliana E. Lucca et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8+ regulatory T cells
- (2021) Alejandro J. Cagnoni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
- (2021) Romain Banchereau et al. Journal for ImmunoTherapy of Cancer
- CD27 expression on Treg cells limits immune responses against tumors
- (2021) Sabine Muth et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity
- (2021) Susan N. Christo et al. NATURE IMMUNOLOGY
- Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human Treg compartment
- (2021) Yuechen Luo et al. Nature Communications
- Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer
- (2021) L. Federico et al. ANNALS OF ONCOLOGY
- Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
- (2021) Jaikumar Duraiswamy et al. CANCER CELL
- Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma
- (2021) Tomohiro Aoki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target
- (2020) Zachary T. Freeman et al. JOURNAL OF CLINICAL INVESTIGATION
- Peripheral T cell expansion predicts tumour infiltration and clinical response
- (2020) Thomas D. Wu et al. NATURE
- The nf-core framework for community-curated bioinformatics pipelines
- (2020) Philip A. Ewels et al. NATURE BIOTECHNOLOGY
- Frontline immunotherapy for NSCLC — the tale of the tail
- (2020) Anne C. Chiang et al. Nature Reviews Clinical Oncology
- Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
- (2020) Hanjie Li et al. CELL
- PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15
- (2020) Kyung Hwan Kim et al. Cellular & Molecular Immunology
- Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy
- (2020) J. Justin Milner et al. IMMUNITY
- IRF4 instructs effector Treg differentiation and immune suppression in human cancer
- (2020) Giorgia Alvisi et al. JOURNAL OF CLINICAL INVESTIGATION
- Dual Relief of T-lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies
- (2020) Camille-Charlotte Balança et al. Cancer Immunology Research
- Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing
- (2020) Nadia S. Kurd et al. Science Immunology
- KLRG1+ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory
- (2020) Kristin R. Renkema et al. JOURNAL OF IMMUNOLOGY
- Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans
- (2020) Giovanni Galletti et al. NATURE IMMUNOLOGY
- Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma
- (2020) Yunfan Sun et al. CELL
- A transcriptionally distinct CXCL13+CD103+CD8+ T-cell population is associated with B-cell recruitment and neoantigen load in human cancer
- (2019) Hagma H Workel et al. Cancer Immunology Research
- Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer
- (2019) Matthew D. Hellmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
- (2019) Yunlong Zhao et al. IMMUNITY
- T Cell Dysfunction in Cancer
- (2018) Daniela S. Thommen et al. CANCER CELL
- KLRG1 + Effector CD8 + T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity
- (2018) Dietmar Herndler-Brandstetter et al. IMMUNITY
- A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade
- (2018) Daniela S. Thommen et al. NATURE MEDICINE
- Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing
- (2018) Xinyi Guo et al. NATURE MEDICINE
- Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients
- (2018) Belinda Palermo et al. OncoImmunology
- Resident memory T cells, critical components in tumor immunology
- (2018) Fathia Mami-Chouaib et al. Journal for ImmunoTherapy of Cancer
- T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
- (2017) Enfu Hui et al. SCIENCE
- Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent
- (2017) Alice O. Kamphorst et al. SCIENCE
- CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination
- (2017) Allison F. Christiaansen et al. VACCINE
- Local Inflammatory Cues Regulate Differentiation and Persistence of CD8 + Tissue-Resident Memory T Cells
- (2017) Tessa Bergsbaken et al. Cell Reports
- Trends and advances in tumor immunology and lung cancer immunotherapy
- (2016) Mohanad Aldarouish et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
- (2016) Se Jin Im et al. NATURE
- Polyfunctional Melan-A-specific tumor-reactive CD8+T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS
- (2016) Ornella Franzese et al. OncoImmunology
- Tissue-Resident Memory T Cells
- (2014) Jason M. Schenkel et al. IMMUNITY
- Dacarbazine Treatment before Peptide Vaccination Enlarges T-Cell Repertoire Diversity of Melan-A-Specific, Tumor-Reactive CTL in Melanoma Patients
- (2010) B. Palermo et al. CANCER RESEARCH
- KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells
- (2009) S. M. Henson et al. BLOOD
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation