Heterogeneity of tissue resident memory T cells

Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets

(2021) Michael E.B. FitzPatrick et al.   Cell Reports

Decoding Tissue-Residency: Programming and Potential of Frontline Memory T Cells

(2021) Simone L. Park et al.   Cold Spring Harbor Perspectives in Biology

Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

(2021) Yang Cheng et al.   IMMUNITY

Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity

(2021) Susan N. Christo et al.   NATURE IMMUNOLOGY

Single-Cell Transcriptomics Reveals Core Regulatory Programs That Determine the Heterogeneity of Circulating and Tissue-Resident Memory CD8+ T Cells

(2021) Yao Chen et al.   Cells

Functions of human liver CD69+CD103-CD8+ T cells depend on HIF-2α activity in healthy and pathologic livers

(2020) Jong Hoon Kim et al.   JOURNAL OF HEPATOLOGY

Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells

(2020) Cristina Ferreira et al.   NATURE IMMUNOLOGY

TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection

(2020) Emma C. Reilly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance

(2020) Bettina Stolp et al.   Science Immunology

Organ-specific isoform selection of fatty acid–binding proteins in tissue-resident lymphocytes

(2020) H. Frizzell et al.   Science Immunology

Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells

(2020) Pierre Bourdely et al.   IMMUNITY

Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes

(2020) Laura J. Pallett et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Long-term maintenance of lung resident memory T cells is mediated by persistent antigen

(2020) Ida Uddbäck et al.   Mucosal Immunology

CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

(2020) Shannon K. Bromley et al.   Cell Reports

The Role of Sinusoidal Endothelial Cells in the Axis of Inflammation and Cancer Within the Liver

(2020) Alex L. Wilkinson et al.   Frontiers in Physiology

Immune surveillance of the liver by T cells

(2020) Xenia Ficht et al.   Science Immunology

ARTC2.2/P2RX7 Signaling during Cell Isolation Distorts Function and Quantification of Tissue-Resident CD8+ T Cell and Invariant NKT Subsets

(2019) Henrique Borges da Silva et al.   JOURNAL OF IMMUNOLOGY

Tissue-Resident T Cells and Other Resident Leukocytes

(2019) David Masopust et al.   Annual Review of Immunology

Tissue patrol by resident memory CD8+ T cells in human skin

(2019) Feline E. Dijkgraaf et al.   NATURE IMMUNOLOGY

Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer

(2019) James Clarke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Location, location, location: Tissue resident memory T cells in mice and humans

(2019) Peter A. Szabo et al.   Science Immunology

Human lung tissue resident memory T cells in health and disease

(2019) Mark E Snyder et al.   CURRENT OPINION IN IMMUNOLOGY

CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways

(2019) Alexander N. Wein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

(2019) Peter A. Szabo et al.   Nature Communications

Tissue-Specific Control of Tissue-Resident Memory T Cells

(2018) Yong Liu et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Human T Cell Development, Localization, and Function throughout Life

(2018) Brahma V. Kumar et al.   IMMUNITY

KLRG1 + Effector CD8 + T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

(2018) Dietmar Herndler-Brandstetter et al.   IMMUNITY

Tissue-resident memory T cells at the center of immunity to solid tumors

(2018) Derk Amsen et al.   NATURE IMMUNOLOGY

In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells

(2018) Björn Rissiek et al.   Frontiers in Immunology

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

(2018) David J. Topham et al.   Frontiers in Immunology

Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells

(2018) Natasja A.M. Kragten et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Metabolic wiring of murine T cell and intraepithelial lymphocyte maintenance and activation

(2018) Marc Veldhoen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tissue resident memory CD8+ T cells mediate salivary gland damage in a murine model of Sjögren's syndrome

(2018) Cai-Yue Gao et al.   Arthritis & Rheumatology

Tissue-resident memory T cells populate the human brain

(2018) Joost Smolders et al.   Nature Communications

Defining Memory CD8 T Cell

(2018) Matthew D. Martin et al.   Frontiers in Immunology

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Chemokine Receptor–Dependent Control of Skin Tissue–Resident Memory T Cell Formation

(2017) Ali Zaid et al.   JOURNAL OF IMMUNOLOGY

The Chemokine Receptor CXCR3 Promotes CD8+T Cell Accumulation in Uninfected Salivary Glands but Is Not Necessary after Murine Cytomegalovirus Infection

(2017) Sofia Caldeira-Dantas et al.   JOURNAL OF IMMUNOLOGY

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

(2016) Daniel Fernandez-Ruiz et al.   IMMUNITY

Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

(2016) Pleun Hombrink et al.   NATURE IMMUNOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Immunosurveillance of the Liver by Intravascular Effector CD8 + T Cells

(2015) Luca G. Guidotti et al.   CELL

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans

(2015) Felipe A. Vieira Braga et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation

(2015) John J. Worthington et al.   IMMUNITY

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

CD161intCD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut

(2015) J R Fergusson et al.   Mucosal Immunology

Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8+ T cells responding to infection

(2015) Tessa Bergsbaken et al.   NATURE IMMUNOLOGY

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Exit Strategies: S1P Signaling and T Cell Migration

(2015) Audrey Baeyens et al.   TRENDS IN IMMUNOLOGY

The Salivary Gland Acts as a Sink for Tissue-Resident Memory CD8 + T Cells, Facilitating Protection from Local Cytomegalovirus Infection

(2015) Jenny Tosca Thom et al.   Cell Reports

The Chemokine Receptor CXCR6 Is Required for the Maintenance of Liver Memory CD8+ T Cells Specific for Infectious Pathogens

(2014) Sze-Wah Tse et al.   JOURNAL OF INFECTIOUS DISEASES

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct resident and recirculating memory T cell subsets in non-lymphoid tissues

(2013) Francis R Carbone et al.   CURRENT OPINION IN IMMUNOLOGY

Human CD1c+ Dendritic Cells Drive the Differentiation of CD103+ CD8+ Mucosal Effector T Cells via the Cytokine TGF-β

(2013) Chun I. Yu et al.   IMMUNITY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

The aryl hydrocarbon receptor in inflammatory bowel disease

(2012) Ivan Monteleone et al.   CURRENT OPINION IN GASTROENTEROLOGY

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

Aryl Hydrocarbon Receptor Is Critical for Homeostasis of Invariant    T Cells in the Murine Epidermis

(2011) S. Kadow et al.   JOURNAL OF IMMUNOLOGY

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE