CTCF is essential for proper mitotic spindle structure and anaphase segregation

Transcription shapes 3D chromatin organization by interacting with loop extrusion

(2023) Edward J. Banigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF supports preferentially short lamina-associated domains

(2022) Lukasz Stanislaw Kaczmarczyk et al.   CHROMOSOME RESEARCH

Mechanics and functional consequences of nuclear deformations

(2022) Yohalie Kalukula et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate

(2022) Charlotte R. Pfeifer et al.   Nucleus

A Versatile Micromanipulation Apparatus for Biophysical Assays of the Cell Nucleus

(2022) Marilena L. Currey et al.   Cellular and Molecular Bioengineering

The phenotypic landscape of essential human genes

(2022) Luke Funk et al.   CELL

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

(2021) Amy R Strom et al.   eLife

Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells

(2021) Patrick J. Flynn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention

(2020) Elena M. Pugacheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics

(2020) Chad M. Hobson et al.   MOLECULAR BIOLOGY OF THE CELL

Advances in Chromatin and Chromosome Research: Perspectives from Multiple Fields

(2020) Andrews Akwasi Agbleke et al.   MOLECULAR CELL

Kinesin-7 CENP-E regulates chromosome alignment and genome stability of spermatogenic cells

(2020) Zhen-Yu She et al.   Cell Death Discovery

Chromatin’s physical properties shape the nucleus and its functions

(2019) Andrew D Stephens et al.   CURRENT OPINION IN CELL BIOLOGY

Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation

(2019) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Common Features of the Pericentromere and Nucleolus

(2019) Colleen J. Lawrimore et al.   Genes

Tetraploidy in cancer and its possible link to aging

(2018) Kozo Tanaka et al.   CANCER SCIENCE

The impact of mitotic errors on cell proliferation and tumorigenesis

(2018) Michelle S. Levine et al.   GENES & DEVELOPMENT

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins

(2018) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Constricted migration increases DNA damage and independently represses cell cycle

(2018) Charlotte R. Pfeifer et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors

(2018) Yuntao Xia et al.   JOURNAL OF CELL BIOLOGY

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

CTCF and cohesin regulate chromatin loop stability with distinct dynamics

(2017) Anders S Hansen et al.   eLife

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness

(2015) Takashi Furusawa et al.   Nature Communications

Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy

(2015) Ailsa Bennett et al.   Oncotarget

CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites

(2015) Tiaojiang Xiao et al.   Cell Reports

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

(2013) V. C. Seitan et al.   GENOME RESEARCH

Individual pericentromeres display coordinated motion and stretching in the yeast spindle

(2013) Andrew D. Stephens et al.   JOURNAL OF CELL BIOLOGY

Fine control of nuclear confinement identifies a threshold deformation leading to lamina rupture and induction of specific genes

(2012) Maël Le Berre et al.   Integrative Biology

Loss of Maternal CTCF Is Associated with Peri-Implantation Lethality of Ctcf Null Embryos

(2012) James M. Moore et al.   PLoS One

CAML loss causes anaphase failure and chromosome missegregation

(2011) Yu Liu et al.   CELL CYCLE

Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring

(2011) Andrew D. Stephens et al.   JOURNAL OF CELL BIOLOGY

Chromosomal regions associated with prostate cancer risk localize to lamin B-deficient microdomains and exhibit reduced gene transcription

(2011) Brian T Helfand et al.   JOURNAL OF PATHOLOGY

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E

(2010) K. W. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Condensin Regulates the Stiffness of Vertebrate Centromeres

(2009) Susana A. Ribeiro et al.   MOLECULAR BIOLOGY OF THE CELL

Abnormal mitosis in hypertetraploid cells causes aberrant nuclear morphology in association with H2O2-induced premature senescence

(2008) Susumu Ohshima   CYTOMETRY PART A

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

(2008) L.-B. Wan et al.   DEVELOPMENT

CTCF physically links cohesin to chromatin

(2008) E. D. Rubio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA