HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Authors
Keywords
-
Journal
eLife
Volume 10, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2021-06-10
DOI
10.7554/elife.63972
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics
- (2021) Houda Belaghzal et al. NATURE GENETICS
- HP1 proteins compact DNA into mechanically and positionally stable phase separated domains
- (2021) Madeline M Keenen et al. eLife
- Dynamic Nuclear Structure Emerges from Chromatin Cross-Links and Motors
- (2021) Kuang Liu et al. PHYSICAL REVIEW LETTERS
- Physical Nature of Chromatin in the Nucleus
- (2021) Kazuhiro Maeshima et al. Cold Spring Harbor Perspectives in Biology
- Liquid-Liquid Phase Separation of Histone Proteins in Cells: Role in Chromatin Organization
- (2020) Anisha Shakya et al. BIOPHYSICAL JOURNAL
- Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
- (2020) Fabian Erdel et al. MOLECULAR CELL
- Chromatin and Cytoskeletal Tethering Determine Nuclear Morphology in Progerin-Expressing Cells
- (2020) Maria Chiara Lionetti et al. BIOPHYSICAL JOURNAL
- Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
- (2020) Michele M. Nava et al. CELL
- The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting
- (2020) Kelly L. Dunlevy et al. JOURNAL OF CELL SCIENCE
- The Emerging Roles of Heterochromatin in Cell Migration
- (2020) Gabi Gerlitz Frontiers in Cell and Developmental Biology
- High-throughput gene screen reveals modulators of nuclear shape
- (2020) Andrew C. Tamashunas et al. MOLECULAR BIOLOGY OF THE CELL
- Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics
- (2020) Chad M. Hobson et al. MOLECULAR BIOLOGY OF THE CELL
- Chromatin rigidity provides mechanical and genome protection
- (2020) Andrew D. Stephens MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Nuclear mechanosensing: mechanism and consequences of a nuclear rupture
- (2020) Gengqiang Xie et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Modeling of Cell Nuclear Mechanics: Classes, Components, and Applications
- (2020) Chad M. Hobson et al. Cells
- Compression stiffening of fibrous networks with stiff inclusions
- (2020) Jordan L. Shivers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells
- (2020) Hilmar Strickfaden et al. CELL
- Comparison of three heterochromatin protein 1 homologs of Drosophila
- (2019) Dong Hoon Lee et al. JOURNAL OF CELL SCIENCE
- Effects of altering histone post-translational modifications on mitotic chromosome structure and mechanics
- (2019) Ronald Biggs et al. MOLECULAR BIOLOGY OF THE CELL
- Chromatin’s physical properties shape the nucleus and its functions
- (2019) Andrew D Stephens et al. CURRENT OPINION IN CELL BIOLOGY
- Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus
- (2019) Marina Krause et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Mitotic Chromosome Mechanics: How Cells Segregate Their Genome
- (2019) Paul Batty et al. TRENDS IN CELL BIOLOGY
- Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions
- (2019) Nimish Khanna et al. Nature Communications
- Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation
- (2019) Andrew D. Stephens et al. MOLECULAR BIOLOGY OF THE CELL
- Organization of Chromatin by Intrinsic and Regulated Phase Separation
- (2019) Bryan A. Gibson et al. CELL
- HP1 reshapes nucleosome core to promote phase separation of heterochromatin
- (2019) S. Sanulli et al. NATURE
- Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance
- (2019) Sahana Holla et al. CELL
- A Transient Rise in Free Mg 2+ Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation
- (2018) Kazuhiro Maeshima et al. CURRENT BIOLOGY
- HP1 links centromeric heterochromatin to centromere cohesion in mammals
- (2018) Qi Yi et al. EMBO REPORTS
- Chromatin organization regulated by EZH2-mediated H3K27me3 is required for OPN-induced migration of bone marrow-derived mesenchymal stem cells
- (2018) Lingling Liu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins
- (2018) Andrew D. Stephens et al. MOLECULAR BIOLOGY OF THE CELL
- Structural Basis of Heterochromatin Formation by Human HP1
- (2018) Shinichi Machida et al. MOLECULAR CELL
- WDR5 modulates cell motility and morphology and controls nuclear changes induced by a 3D environment
- (2018) Pengbo Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A pathway for mitotic chromosome formation
- (2018) Johan H. Gibcus et al. SCIENCE
- Cryo-EM of nucleosome core particle interactions in trans
- (2018) Silvija Bilokapic et al. Scientific Reports
- Liquid-Liquid Phase Separation in an Elastic Network
- (2018) Robert W. Style et al. Physical Review X
- Condensin controls mitotic chromosome stiffness and stability without forming a structurally contiguous scaffold
- (2018) Mingxuan Sun et al. CHROMOSOME RESEARCH
- Nuclear rupture at sites of high curvature compromises retention of DNA repair factors
- (2018) Yuntao Xia et al. JOURNAL OF CELL BIOLOGY
- Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome
- (2018) Yongdae Shin et al. CELL
- Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus
- (2017) Andrew D. Stephens et al. MOLECULAR BIOLOGY OF THE CELL
- Phase separation drives heterochromatin domain formation
- (2017) Amy R. Strom et al. NATURE
- Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
- (2017) Adam G. Larson et al. NATURE
- Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization
- (2017) Laia Bosch-Presegué et al. Cell Reports
- Mitotic post-translational modifications of histones promote chromatin compaction in vitro
- (2017) Alisa Zhiteneva et al. Open Biology
- Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
- (2017) Tyler S Harmon et al. eLife
- Lamin B Receptor: Interplay between Structure, Function and Localization
- (2017) Eleni Nikolakaki et al. Cells
- Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR)
- (2017) Ioannis Giannios et al. PLoS One
- HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation Errors
- (2016) Yusuke Abe et al. DEVELOPMENTAL CELL
- Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity
- (2016) Su-Jin Heo et al. eLife
- In silico synchronization reveals regulators of nuclear ruptures in lamin A/C deficient model cells
- (2016) J. Robijns et al. Scientific Reports
- Beyond the histone tale: HP1α deregulation in breast cancer epigenetics
- (2015) Johan Vad-Nielsen et al. CANCER BIOLOGY & THERAPY
- Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness
- (2015) Takashi Furusawa et al. Nature Communications
- Multivalency governs HP1α association dynamics with the silent chromatin state
- (2015) Sinan Kilic et al. Nature Communications
- The tethering of chromatin to the nuclear envelope supports nuclear mechanics
- (2015) Sarah M. Schreiner et al. Nature Communications
- Human Heterochromatin Protein 1α Promotes Nucleosome Associations That Drive Chromatin Condensation
- (2014) Abdelhamid M. Azzaz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Spatiotemporal Dynamics of Chromatin Protein HP1α Is Essential for Accurate Chromosome Segregation during Cell Division
- (2014) Lingluo Chu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Dynamic phosphorylation of HP1α regulates mitotic progression in human cells
- (2014) Arindam Chakraborty et al. Nature Communications
- LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation
- (2013) Irina Solovei et al. CELL
- Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin
- (2013) M. Hahn et al. GENES & DEVELOPMENT
- HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response
- (2013) Young-Ho Lee et al. NUCLEIC ACIDS RESEARCH
- The Human Protein PRR14 Tethers Heterochromatin to the Nuclear Lamina during Interphase and Mitotic Exit
- (2013) Andrey Poleshko et al. Cell Reports
- Dynamics and Memory of Heterochromatin in Living Cells
- (2012) Nathaniel A. Hathaway et al. CELL
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair
- (2011) Irene Chiolo et al. CELL
- KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state
- (2011) David Frescas et al. CELL CYCLE
- Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring
- (2011) Andrew D. Stephens et al. JOURNAL OF CELL BIOLOGY
- Chromodomain-Mediated Oligomerization of HP1 Suggests a Nucleosome-Bridging Mechanism for Heterochromatin Assembly
- (2011) Daniele Canzio et al. MOLECULAR CELL
- H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing
- (2011) Irina A Maksakova et al. Epigenetics & Chromatin
- Heterochromatin protein 1 (HP1) modulates replication timing of the Drosophila genome
- (2010) M. Schwaiger et al. GENOME RESEARCH
- Mitotic chromosomes are constrained by topoisomerase II–sensitive DNA entanglements
- (2010) Ryo Kawamura et al. JOURNAL OF CELL BIOLOGY
- Condensin Regulates the Stiffness of Vertebrate Centromeres
- (2009) Susana A. Ribeiro et al. MOLECULAR BIOLOGY OF THE CELL
- An auxin-based degron system for the rapid depletion of proteins in nonplant cells
- (2009) Kohei Nishimura et al. NATURE METHODS
- Heterochromatin Protein 1 (HP1) Proteins Do Not Drive Pericentromeric Cohesin Enrichment in Human Cells
- (2009) Ángel Serrano et al. PLoS One
- Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast
- (2009) T. Fischer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Balance between Distinct HP1 Family Proteins Controls Heterochromatin Assembly in Fission Yeast
- (2008) M. Sadaie et al. MOLECULAR AND CELLULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started