Common Features of the Pericentromere and Nucleolus

Compositional reorganization of the nucleolus in budding yeast mitosis

(2019) Philipp Girke et al.   MOLECULAR BIOLOGY OF THE CELL

A folded conformation of MukBEF and cohesin

(2019) Frank Bürmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transfer RNA Genes Affect Chromosome Structure and Function via Local Effects

(2019) Omar Hamdani et al.   MOLECULAR AND CELLULAR BIOLOGY

Condensins and cohesins – one of these things is not like the other!

(2019) Robert V. Skibbens   JOURNAL OF CELL SCIENCE

Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations

(2019) Henrike Johanna Gothe et al.   MOLECULAR CELL

The nucleolus functions as a phase-separated protein quality control compartment

(2019) F. Frottin et al.   SCIENCE

The regulation of chromosome segregation via centromere loops

(2019) Josh Lawrimore et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Quantification of the dynamic behaviour of ribosomal DNA genes and nucleolus during yeast Saccharomyces cerevisiae cell cycle

(2019) Lise Dauban et al.   JOURNAL OF STRUCTURAL BIOLOGY

The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex

(2019) Prasad Trivedi et al.   NATURE CELL BIOLOGY

The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies

(2019) Carl C. Correll et al.   Cells

DNA loop extrusion by human cohesin

(2019) Iain F. Davidson et al.   SCIENCE

The ribosomal DNA metaphase loop of Saccharomyces cerevisiae gets condensed upon heat stress in a Cdc14-independent TORC1-dependent manner

(2018) Emiliano Matos-Perdomo et al.   CELL CYCLE

HP1 links centromeric heterochromatin to centromere cohesion in mammals

(2018) Qi Yi et al.   EMBO REPORTS

Chromatin organization by an interplay of loop extrusion and compartmental segregation

(2018) Johannes Nuebler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time imaging of DNA loop extrusion by condensin

(2018) Mahipal Ganji et al.   SCIENCE

Geometric partitioning of cohesin and condensin are a consequence of chromatin loops

(2018) Josh Lawrimore et al.   MOLECULAR BIOLOGY OF THE CELL

Pericentromere-Specific Cohesin Complex Prevents Meiotic Pericentric DNA Double-Strand Breaks and Lethal Crossovers

(2018) Mridula Nambiar et al.   MOLECULAR CELL

Fork pausing allows centromere DNA loop formation and kinetochore assembly

(2018) Diana M. Cook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membraneless nuclear organelles and the search for phases within phases

(2018) Iain A. Sawyer et al.   Wiley Interdisciplinary Reviews-RNA

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus

(2017) Caitlin Hult et al.   NUCLEIC ACIDS RESEARCH

The condensin complex is a mechanochemical motor that translocates along DNA

(2017) Tsuyoshi Terakawa et al.   SCIENCE

Potential Role of Phase Separation of Repetitive DNA in Chromosomal Organization

(2017) Shao-Jun Tang   Genes

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Insights into epigenetic landscape of recombination-free regions

(2016) Pasquale Termolino et al.   CHROMOSOMA

Decoding the principles underlying the frequency of association with nucleoli for RNA polymerase III–transcribed genes in budding yeast

(2016) Praveen Belagal et al.   MOLECULAR BIOLOGY OF THE CELL

ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin

(2016) Josh Lawrimore et al.   MOLECULAR BIOLOGY OF THE CELL

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression

(2016) Antoine Aze et al.   NATURE CELL BIOLOGY

Entropy gives rise to topologically associating domains

(2016) Paula A. Vasquez et al.   NUCLEIC ACIDS RESEARCH

Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin

(2016) Johannes Stigler et al.   Cell Reports

Formation of Chromosomal Domains by Loop Extrusion

(2016) Geoffrey Fudenberg et al.   Cell Reports

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation

(2015) Andrew D Stephens et al.   CELL CYCLE

Inverse Size Scaling of the Nucleolus by a Concentration-Dependent Phase Transition

(2015) Stephanie C. Weber et al.   CURRENT BIOLOGY

Principles of chromatin organization in yeast: relevance of polymer models to describe nuclear organization and dynamics

(2015) Renjie Wang et al.   CURRENT OPINION IN CELL BIOLOGY

The role of loops on the order of eukaryotes and prokaryotes

(2015) Andreas Hofmann et al.   FEBS LETTERS

DNA loops generate intracentromere tension in mitosis

(2015) Josh Lawrimore et al.   JOURNAL OF CELL BIOLOGY

CTCF Binding Polarity Determines Chromatin Looping

(2015) Elzo de Wit et al.   MOLECULAR CELL

Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

(2015) Kamilla Mundbjerg et al.   PLoS Genetics

Re-replication of a Centromere Induces Chromosomal Instability and Aneuploidy

(2015) Stacey L. Hanlon et al.   PLoS Genetics

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Dyskerin, tRNA genes, and condensin tether pericentric chromatin to the spindle axis in mitosis

(2014) Chloe E. Snider et al.   JOURNAL OF CELL BIOLOGY

Ribosomal RNA gene repeats, their stability and cellular senescence

(2014) Takehiko KOBAYASHI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Recombination and Replication

(2014) A. H. Syeda et al.   Cold Spring Harbor Perspectives in Biology

Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

(2014) A. Mehta et al.   Cold Spring Harbor Perspectives in Biology

Centromeres in nuclear architecture

(2013) Jan Padeken et al.   CELL CYCLE

The Composition, Functions, and Regulation of the Budding Yeast Kinetochore

(2013) Sue Biggins   GENETICS

Ribosomal RNA Gene Transcription Mediated by the Master Genome Regulator Protein CCCTC-binding Factor (CTCF) Is Negatively Regulated by the Condensin Complex

(2013) Kaimeng Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The spatial segregation of pericentric cohesin and condensin in the mitotic spindle

(2013) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Cohesion promotes nucleolar structure and function

(2013) Bethany Harris et al.   MOLECULAR BIOLOGY OF THE CELL

Centromere Tethering Confines Chromosome Domains

(2013) Jolien Suzanne Verdaasdonk et al.   MOLECULAR CELL

Genome-wide analysis of functional sirtuin chromatin targets in yeast

(2013) Mingguang Li et al.   GENOME BIOLOGY

A Predictive Computational Model of the Dynamic 3D Interphase Yeast Nucleus

(2012) Hua Wong et al.   CURRENT BIOLOGY

CTCF: insights into insulator function during development

(2012) M. Herold et al.   DEVELOPMENT

Condensins: universal organizers of chromosomes with diverse functions

(2012) T. Hirano   GENES & DEVELOPMENT

Physical tethering and volume exclusion determine higher-order genome organization in budding yeast

(2012) H. Tjong et al.   GENOME RESEARCH

Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells

(2012) Tania Bose et al.   PLoS Genetics

Human tRNA genes function as chromatin insulators

(2011) Jesse R Raab et al.   EMBO JOURNAL

Reinventing Heterochromatin in Budding Yeasts: Sir2 and the Origin Recognition Complex Take Center Stage

(2011) Meleah A. Hickman et al.   EUKARYOTIC CELL

Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring

(2011) Andrew D. Stephens et al.   JOURNAL OF CELL BIOLOGY

Centromeres: unique chromatin structures that drive chromosome segregation

(2011) Jolien S. Verdaasdonk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrative genomic analysis of human ribosomal DNA

(2011) Gabriel E. Zentner et al.   NUCLEIC ACIDS RESEARCH

The CCCTC-Binding Factor (CTCF) of Drosophila Contributes to the Regulation of the Ribosomal DNA and Nucleolar Stability

(2011) Paola A. Guerrero et al.   PLoS One

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

(2011) C. P. Brangwynne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positive Supercoiling of Mitotic DNA Drives Decatenation by Topoisomerase II in Eukaryotes

(2011) J. Baxter et al.   SCIENCE

Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains

(2010) María Mayan et al.   CELL CYCLE

Systematic Reduction of Cohesin Differentially Affects Chromosome Segregation, Condensation, and DNA Repair

(2010) Jill M. Heidinger-Pauli et al.   CURRENT BIOLOGY

DNA ligase 4 stabilizes the ribosomal DNA array upon fork collapse at the replication fork barrier

(2010) Olivier Fritsch et al.   DNA REPAIR

Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements

(2010) Daniele Fachinetti et al.   MOLECULAR CELL

Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors

(2010) Andrew J Oler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A super-resolution map of the vertebrate kinetochore

(2010) S. A. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensing centromere tension: Aurora B and the regulation of kinetochore function

(2010) Michael A. Lampson et al.   TRENDS IN CELL BIOLOGY

A role for recombination in centromere function

(2010) Ramsay J. McFarlane et al.   TRENDS IN GENETICS

CTCF regulates the local epigenetic state of ribosomal DNA repeats

(2010) Suzanne van de Nobelen et al.   Epigenetics & Chromatin

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

Loss of the insulator protein CTCF during nematode evolution

(2009) Peter Heger et al.   BMC MOLECULAR BIOLOGY

Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism

(2009) K. Mizuno et al.   GENES & DEVELOPMENT

Cohesinopathy mutations disrupt the subnuclear organization of chromatin

(2009) Scarlett Gard et al.   JOURNAL OF CELL BIOLOGY

Pericentromeric Sister Chromatid Cohesion Promotes Kinetochore Biorientation

(2009) Tessie M. Ng et al.   MOLECULAR BIOLOGY OF THE CELL

Centromeric Localization of Dispersed Pol III Genes in Fission Yeast

(2009) Osamu Iwasaki et al.   MOLECULAR BIOLOGY OF THE CELL

Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility

(2009) Irina Voineagu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1

(2009) D. W. Pryce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Fine-Structure Map of Spontaneous Mitotic Crossovers in the Yeast Saccharomyces cerevisiae

(2009) Phoebe S. Lee et al.   PLoS Genetics

Establishment of Cohesion at the Pericentromere by the Ctf19 Kinetochore Subcomplex and the Replication Fork-Associated Factor, Csm3

(2009) Josefin Fernius et al.   PLoS Genetics

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

Pericentric Chromatin Is Organized into an Intramolecular Loop in Mitosis

(2008) Elaine Yeh et al.   CURRENT BIOLOGY

Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation

(2008) Claudio D'Ambrosio et al.   CURRENT BIOLOGY

Clustering of yeast tRNA genes is mediated by specific association of condensin with tRNA gene transcription complexes

(2008) R. A. Haeusler et al.   GENES & DEVELOPMENT

Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules

(2008) K. Merz et al.   GENES & DEVELOPMENT

Identification of cis-acting sites for condensin loading onto budding yeast chromosomes

(2008) C. D'Ambrosio et al.   GENES & DEVELOPMENT

Centromere mitotic recombination in mammalian cells

(2008) Isabel Jaco et al.   JOURNAL OF CELL BIOLOGY

Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis

(2008) Norihiko Nakazawa et al.   JOURNAL OF CELL BIOLOGY

DNA Topoisomerase II Is a Determinant of the Tensile Properties of Yeast Centromeric Chromatin and the Tension Checkpoint

(2008) Tariq H. Warsi et al.   MOLECULAR BIOLOGY OF THE CELL

Cohesin mediates transcriptional insulation by CCCTC-binding factor

(2008) Kerstin S. Wendt et al.   NATURE

Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins

(2008) I. Voineagu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA