Role of Metabolic Adaptation of Streptococcus suis to Host Niches in Bacterial Fitness and Virulence

The antimicrobial systems of Streptococcus suis promote niche competition in pig tonsils

(2022) Zijing Liang et al.   Virulence

Interplay of CodY and CcpA in Regulating Central Metabolism and Biofilm Formation in Staphylococcus aureus

(2022) Logan L. Bulock et al.   JOURNAL OF BACTERIOLOGY

Streptococcus suis TrpX is part of a tryptophan uptake system, and its expression is regulated by a T-box regulatory element

(2022) Muriel Dresen et al.   Scientific Reports

Effects of l -Serine on Macrolide Resistance in Streptococcus suis

(2022) Tong Wu et al.   Microbiology Spectrum

Environmental and maternal factors shaping tonsillar microbiota development in piglets

(2022) Simen Fredriksen et al.   BMC MICROBIOLOGY

Comparative transcriptomic analysis reveal genes involved in the pathogenicity increase of Streptococcus suis epidemic strains

(2022) Jianping Wang et al.   Virulence

Exogenous glycogen utilization effects the transcriptome and pathogenicity of Streptococcus suis serotype 2

(2022) Mei-Fang Tan et al.   Frontiers in Cellular and Infection Microbiology

A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of Hypoxia

(2021) Alexa N. Lauer et al.   Frontiers in Cellular and Infection Microbiology

Comprehensive analysis of bacteriocins in Streptococcus mutans

(2021) Atsuko Watanabe et al.   Scientific Reports

The impact of carbon and nitrogen catabolite repression in microorganisms

(2021) Abhinav Nair et al.   MICROBIOLOGICAL RESEARCH

Coinfection with porcine circovirus type 2 and Streptococcus suis serotype 2 enhances pathogenicity by dysregulation of the immune responses in piglets

(2020) Qing Wang et al.   VETERINARY MICROBIOLOGY

In vitro Mixed Biofilm of Streptococcus suis and Actinobacillus pleuropneumoniae Impacts Antibiotic Susceptibility and Modulates Virulence Factor Gene Expression

(2020) Yang Wang et al.   Frontiers in Microbiology

Coinfection with Porcine Circovirus Type 2 (PCV2) and Streptococcus suis Serotype 2 (SS2) Enhances the Survival of SS2 in Swine Tracheal Epithelial Cells by Decreasing Reactive Oxygen Species Production

(2020) Qing Wang et al.   INFECTION AND IMMUNITY

Antimicrobial resistance phenotypes and genotypes of Streptococcus suis isolated from clinically healthy pigs from 2017 to 2019 in Jiangxi Province, China

(2020) M.‐F. Tan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Genome Reduction Is Associated with Bacterial Pathogenicity across Different Scales of Temporal and Ecological Divergence

(2020) Gemma G R Murray et al.   MOLECULAR BIOLOGY AND EVOLUTION

Bordetella bronchiseptica promotes adherence, colonization, and cytotoxicity of Streptococcus suis in a porcine precision-cut lung slice model

(2020) Désirée Vötsch et al.   Virulence

In vitro and in vivo activity of d-serine in combination with β-lactam antibiotics against methicillin-resistant Staphylococcus aureus

(2019) Qing Wang et al.   Acta Pharmaceutica Sinica B

Structures and characteristics of carbohydrates in diets fed to pigs: a review

(2019) Diego M. D. L. Navarro et al.   Journal of Animal Science and Biotechnology

Bacterial Metabolism and Antibiotic Efficacy

(2019) Jonathan M. Stokes et al.   Cell Metabolism

Characterization of pig saliva as the major natural habitat of Streptococcus suis by analyzing oral, fecal, vaginal, and environmental microbiota

(2019) Kazunori Murase et al.   PLoS One

Selective substrate uptake: The role of ATP-binding cassette (ABC) importers in pathogenesis

(2018) Kari J. Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Streptococcus suis – The “Two Faces” of a Pathobiont in the Porcine Respiratory Tract

(2018) Désirée Vötsch et al.   Frontiers in Microbiology

The Redox-Sensing Regulator Rex Contributes to the Virulence and Oxidative Stress Response of Streptococcus suis Serotype 2

(2018) Haodan Zhu et al.   Frontiers in Cellular and Infection Microbiology

Porcine reproductive and respiratory syndrome virus NADC30-like strain accelerates Streptococcus suis serotype 2 infection in vivo and in vitro

(2018) Jianda Li et al.   Transboundary and Emerging Diseases

Comparison of Oropharyngeal Microbiota in Healthy Piglets and Piglets With Respiratory Disease

(2018) Qun Wang et al.   Frontiers in Microbiology

CodY, a master integrator of metabolism and virulence in Gram-positive bacteria

(2016) Shaun R. Brinsmade   CURRENT GENETICS

Metabolic traits of pathogenic streptococci

(2016) Jörg Willenborg et al.   FEBS LETTERS

Initial steps of the pathogenesis of the infection caused byStreptococcus suis: fighting against nonspecific defenses

(2016) Mariela Segura et al.   FEBS LETTERS

Biological activities of suilysin: role inStreptococcus suispathogenesis

(2016) Tobias Tenenbaum et al.   Future Microbiology

Riboswitches: From living biosensors to novel targets of antibiotics

(2016) Elnaz Mehdizadeh Aghdam et al.   GENE

Transcriptional Analysis of PRRSV-Infected Porcine Dendritic Cell Response to Streptococcus suis Infection Reveals Up-Regulation of Inflammatory-Related Genes Expression

(2016) Gaël Auray et al.   PLoS One

Efficient suilysin-mediated invasion and apoptosis in porcine respiratory epithelial cells after streptococcal infection under air-liquid interface conditions

(2016) Fandan Meng et al.   Scientific Reports

The CodY regulator is essential for virulence in Streptococcus suis serotype 2

(2016) Liping Feng et al.   Scientific Reports

Boosting Bacterial Metabolism to Combat Antibiotic Resistance

(2015) Prerna Bhargava et al.   Cell Metabolism

Exogenous Alanine and/or Glucose plus Kanamycin Kills Antibiotic-Resistant Bacteria

(2015) Bo Peng et al.   Cell Metabolism

A multifaceted ‘omics’ approach for addressing the challenge of antimicrobial resistance

(2015) Asi Cohen et al.   Future Microbiology

Dynamic Virus-Bacterium Interactions in a Porcine Precision-Cut Lung Slice Coinfection Model: Swine Influenza Virus Paves the Way for Streptococcus suis Infection in a Two-Step Process

(2015) F. Meng et al.   INFECTION AND IMMUNITY

Generic determinants of Streptococcus colonization and infection

(2015) Angela H. Nobbs et al.   INFECTION GENETICS AND EVOLUTION

Characterization of the Pivotal Carbon Metabolism ofStreptococcus suisSerotype 2 underex Vivoand Chemically Definedin VitroConditions by Isotopologue Profiling

(2015) Jörg Willenborg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialic acid-dependent interactions between influenza viruses and Streptococcus suis affect the infection of porcine tracheal cells

(2015) Nai-Huei Wu et al.   JOURNAL OF GENERAL VIROLOGY

Catabolite control protein A has an important role in the metabolic regulation of Streptococcus suis type 2 according to iTRAQ-based quantitative proteomic analysis

(2015) XULONG LANG et al.   Molecular Medicine Reports

Investigation into the role of catabolite control protein A in the metabolic regulation of Streptococcus suis serotype 2 using gene expression profile analysis

(2015) XULONG LANG et al.   Experimental and Therapeutic Medicine

The Role of Microbial Amino Acid Metabolism in Host Metabolism

(2015) Evelien Neis et al.   Nutrients

Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis

(2014) Yuan Dang et al.   BMC Veterinary Research

The CcpA regulon ofStreptococcus suisreveals novel insights into the regulation of the streptococcal central carbon metabolism by binding of CcpA to two distinct binding motifs

(2014) Jörg Willenborg et al.   MOLECULAR MICROBIOLOGY

Carbohydrate Availability Regulates Virulence Gene Expression in Streptococcus suis

(2014) M. Laura Ferrando et al.   PLoS One

Two Spx Regulators Modulate Stress Tolerance and Virulence in Streptococcus suis Serotype 2

(2014) Chengkun Zheng et al.   PLoS One

The Streptococcus suis transcriptional landscape reveals adaptation mechanisms in pig blood and cerebrospinal fluid

(2014) Z. Wu et al.   RNA

The arginine-ornithine antiporter ArcD contributes to biological fitness of Streptococcus suis

(2014) Marcus Fulde et al.   Frontiers in Cellular and Infection Microbiology

The role of metabolism in bacterial persistence

(2014) Stephanie M. Amato et al.   Frontiers in Microbiology

Transcriptomic and genomic evidence for Streptococcus agalactiae adaptation to the bovine environment

(2013) Vincent P Richards et al.   BMC GENOMICS

Capsular Sialic Acid of Streptococcus suis Serotype 2 Binds to Swine Influenza Virus and Enhances Bacterial Interactions with Virus-Infected Tracheal Epithelial Cells

(2013) Yingchao Wang et al.   INFECTION AND IMMUNITY

The Contribution of Suilysin to the Pathogenesis of Streptococcus suis Meningitis

(2013) Dan Takeuchi et al.   JOURNAL OF INFECTIOUS DISEASES

Novel Regulatory Small RNAs in Streptococcus pyogenes

(2013) Rafael A. Tesorero et al.   PLoS One

Effect of Spatial Separation of Pigs on Spread of Streptococcus suis Serotype 9

(2013) Niels Dekker et al.   PLoS One

Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance

(2013) N. M. Vega et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subcytolytic effects of suilysin on interaction of Streptococcus suis with epithelial cells

(2013) M. Seitz et al.   VETERINARY MICROBIOLOGY

Virulence factors involved in the pathogenesis of the infection caused by the swine pathogen and zoonotic agent Streptococcus suis

(2012) Nahuel Fittipaldi et al.   Future Microbiology

Catabolite control protein a of Streptococcus suis type 2 contributes to sugar metabolism and virulence

(2012) Yulong Tang et al.   JOURNAL OF MICROBIOLOGY

The two-component system Ihk/Irr contributes to the virulence of Streptococcus suis serotype 2 strain 05ZYH33 through alteration of the bacterial cell metabolism

(2012) H. Han et al.   MICROBIOLOGY-SGM

A Functional Genomics Approach to Establish the Complement of Carbohydrate Transporters in Streptococcus pneumoniae

(2012) Alessandro Bidossi et al.   PLoS One

Polar Invasion and Translocation of Neisseria meningitidis and Streptococcus suis in a Novel Human Model of the Blood-Cerebrospinal Fluid Barrier

(2012) Christian Schwerk et al.   PLoS One

HP0197 Contributes to CPS Synthesis and the Virulence of Streptococcus suis via CcpA

(2012) Anding Zhang et al.   PLoS One

Control of Virulence by Small RNAs in Streptococcus pneumoniae

(2012) Beth Mann et al.   PLoS Pathogens

Fluoroquinolone Efflux in Streptococcus suis Is Mediated by SatAB and Not by SmrA

(2011) Jose Antonio Escudero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Analysis of microRNA-size, small RNAs in Streptococcus mutans by deep sequencing

(2011) Heon-Jin Lee et al.   FEMS MICROBIOLOGY LETTERS

In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis: release of pro-inflammatory cytokines and chemokines

(2011) Christian Schwerk et al.   MICROBES AND INFECTION

Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis

(2011) J. Willenborg et al.   MICROBIOLOGY-SGM

CcpA regulates biofilm formation and competence in Streptococcus gordonii

(2011) L. Zheng et al.   Molecular Oral Microbiology

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

(2011) Elitza Deltcheva et al.   NATURE

An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains

(2011) Christophe Pichon et al.   NUCLEIC ACIDS RESEARCH

Are pathogenic bacteria just looking for food? Metabolism and microbial pathogenesis

(2011) Laurence Rohmer et al.   TRENDS IN MICROBIOLOGY

Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen

(2011) Claudio Palmieri et al.   Frontiers in Microbiology

Polymicrobial respiratory disease in pigs

(2011) T. Opriessnig et al.   ANIMAL HEALTH RESEARCH REVIEWS

Identification of novel non-coding small RNAs from Streptococcus pneumoniae TIGR4 using high-resolution genome tiling arrays

(2010) Ranjit Kumar et al.   BMC GENOMICS

Reduced virulence is an important characteristic of biofilm infection of Streptococcus suis

(2010) Yang Wang et al.   FEMS MICROBIOLOGY LETTERS

Streptococcus suis: a new emerging or an old neglected zoonotic pathogen?

(2010) Marcelo Gottschalk et al.   Future Microbiology

ArgR is an essential local transcriptional regulator of the arcABC operon in Streptococcus suis and is crucial for biological fitness in an acidic environment

(2010) M. Fulde et al.   MICROBIOLOGY-SGM

ApuA, a multifunctional  -glucan-degrading enzyme of Streptococcus suis, mediates adhesion to porcine epithelium and mucus

(2010) M. L. Ferrando et al.   MICROBIOLOGY-SGM

Microarray analyses of THP-1 cells infected with Streptococcus suis serotype 2

(2010) Manli Liu et al.   VETERINARY MICROBIOLOGY

The two-component regulatory system CiaRH contributes to the virulence of Streptococcus suis 2

(2010) Jinquan Li et al.   VETERINARY MICROBIOLOGY

Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis

(2009) Matthew T. G. Holden et al.   PLoS One

Identification of a surface protective antigen, HP0197 of Streptococcus suis serotype 2

(2009) Anding Zhang et al.   VACCINE

Involvement of NF-κB and MAP-kinases in the transcriptional response of alveolar macrophages to Streptococcus suis

(2009) Astrid de Greeff et al.   VETERINARY MICROBIOLOGY

4,5-Disubstituted oxazolidinones: High affinity molecular effectors of RNA function

(2008) Rajaneesh Anupam et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dexamethasone prevents alteration of tight junction-associated proteins and barrier function in porcine choroid plexus epithelial cells after infection with Streptococcus suis in vitro

(2008) Tobias Tenenbaum et al.   BRAIN RESEARCH

Clinical, Experimental, and Genomic Differences between Intermediately Pathogenic, Highly Pathogenic, and EpidemicStreptococcus suis

(2008) Changyun Ye et al.   JOURNAL OF INFECTIOUS DISEASES

Carbon catabolite repression in bacteria: many ways to make the most out of nutrients

(2008) Boris Görke et al.   NATURE REVIEWS MICROBIOLOGY

A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus

(2008) S. A. Shelburne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of immunogenic cell wall-associated proteins of Streptococcus suis serotype 2

(2008) Anding Zhang et al.   PROTEOMICS

The role of complex carbohydrate catabolism in the pathogenesis of invasive streptococci

(2008) Samuel A. Shelburne et al.   TRENDS IN MICROBIOLOGY

Polysaccharide capsule and suilysin contribute to extracellular survival of Streptococcus suis co-cultivated with primary porcine phagocytes

(2008) Laurentiu Benga et al.   VETERINARY MICROBIOLOGY

Characterisation of biofilm formation by a Streptococcus suis meningitis isolate

(2007) Daniel Grenier et al.   VETERINARY JOURNAL

Comparative evaluation of virulence and pathology of Streptococcus suis serotypes 2 and 9 in experimentally infected growers

(2007) Andreas Beineke et al.   VETERINARY MICROBIOLOGY