Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems

Immune-Epithelial Cross Talk in Regeneration and Repair

(2023) Laure Guenin-Mace et al.   Annual Review of Immunology

One Size Does Not Fit All: Diversifying Immune Function in the Skin

(2022) Shruti Naik   JOURNAL OF IMMUNOLOGY

An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes

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Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation

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Inflammatory memory and tissue adaptation in sickness and in health

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Interleukin-17 governs hypoxic adaptation of injured epithelium

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Developmental cell programs are co-opted in inflammatory skin disease

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Suppression of IL-23-mediated psoriasis-like inflammation by regulatory B cells

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Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity

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Cytokine responses in nonlesional psoriatic skin as clinical predictor to anti-TNF agents

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Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas

(2020) Reuben Moncada et al.   NATURE BIOTECHNOLOGY

Role of regulatory T cells in psoriasis pathogenesis and treatment

(2020) L. Nussbaum et al.   BRITISH JOURNAL OF DERMATOLOGY

Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies

(2020) Travis K. Hughes et al.   IMMUNITY

Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer

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Skin-Associated B Cells in the Pathogenesis of Cutaneous Autoimmune Diseases—Implications for Therapeutic Approaches

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Preventing psoriatic arthritis: focusing on patients with psoriasis at increased risk of transition

(2019) Jose U. Scher et al.   Nature Reviews Rheumatology

Choreographing Immunity in the Skin Epithelial Barrier

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Localization of treatment‐resistant areas in patients with psoriasis on biologics

(2019) K.F. Hjuler et al.   BRITISH JOURNAL OF DERMATOLOGY

Comprehensive Integration of Single-Cell Data

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FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR

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Fast, sensitive and accurate integration of single-cell data with Harmony

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Visualizing structure and transitions in high-dimensional biological data

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NicheNet: modeling intercellular communication by linking ligands to target genes

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Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis

(2018) Li-Hao Huang et al.   Cell Metabolism

An IL-17–dominant immune profile is shared across the major orphan forms of ichthyosis

(2017) Amy S. Paller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis

(2017) Andrew Johnston et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The psychosocial burden of psoriatic arthritis

(2017) M. Elaine Husni et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

CD19+ B cell subsets in the peripheral blood and skin lesions of psoriasis patients and their correlations with disease severity

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IL-10-producing regulatory B cells are decreased in patients with psoriasis

(2016) Mitsuha Hayashi et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

(2016) Laure Rittié et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes

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Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

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Psoriasis, psoriatic arthritis, and rheumatoid arthritis: Is all inflammation the same?

(2016) Laura C. Coates et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

The Incidence and Risk Factors for Psoriatic Arthritis in Patients With Psoriasis: A Prospective Cohort Study

(2016) Lihi Eder et al.   Arthritis & Rheumatology

Psoriatic alopecia

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Increased circulating follicular helper T cells and activated B cells correlate with disease severity in patients with psoriasis

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Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

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Transcriptome Analysis of Psoriasis in a Large Case–Control Sample: RNA-Seq Provides Insights into Disease Mechanisms

(2014) Bingshan Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

High prevalence of psoriatic arthritis in patients with severe psoriasis with suboptimal performance of screening questionnaires

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New insights of T cells in the pathogenesis of psoriasis

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Compartmentalized Control of Skin Immunity by Resident Commensals

(2012) S. Naik et al.   SCIENCE

IL-17A Upregulates Keratin 17 Expression in Keratinocytes through STAT1- and STAT3-Dependent Mechanisms

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Cardiovascular and other comorbidities in patients with psoriatic arthritis: A comparison with patients with psoriasis

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Prevalence of the Metabolic Syndrome in Psoriasis

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FGFR3 mutation affects cell growth, apoptosis and attachment in keratinocytes

(2010) Christian Hafner et al.   EXPERIMENTAL CELL RESEARCH

Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis

(2010) Jingxuan Yang et al.   JOURNAL OF CELL BIOLOGY

Risk factors associated with having psoriatic arthritis in patients with cutaneous psoriasis

(2010) Hong Liang TEY et al.   JOURNAL OF DERMATOLOGY

Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: A population-based study

(2009) Floranne C. Wilson et al.   ARTHRITIS AND RHEUMATISM

Evaluation of insulin resistance in obese women with and without acanthosis nigricans

(2009) Giti SADEGHIAN et al.   JOURNAL OF DERMATOLOGY