Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity

Tissue Determinants of Human NK Cell Development, Function, and Residence

(2020) Pranay Dogra et al.   CELL

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

Single-cell transcriptional diversity is a hallmark of developmental potential

(2020) Gunsagar S. Gulati et al.   SCIENCE

A conserved dendritic-cell regulatory program limits antitumour immunity

(2020) Barbara Maier et al.   NATURE

Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human

(2020) Juanjuan Zhao et al.   Cell Discovery

Generalizing RNA velocity to transient cell states through dynamical modeling

(2020) Volker Bergen et al.   NATURE BIOTECHNOLOGY

DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus

(2020) Pedram Shafiei-Jahani et al.   Nature Communications

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

(2019) Diego Adhemar Jaitin et al.   CELL

KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2− ILCs biased toward ILC2 or ILC3

(2019) Maho Nagasawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A cellular census of human lungs identifies novel cell states in health and in asthma

(2019) Felipe A. Vieira Braga et al.   NATURE MEDICINE

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells

(2019) Charles-Antoine Dutertre et al.   IMMUNITY

Spatiotemporal immune zonation of the human kidney

(2019) Benjamin J. Stewart et al.   SCIENCE

Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity

(2019) Chrysothemis C. Brown et al.   CELL

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

(2019) Peter A. Szabo et al.   Nature Communications

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

(2019) H.-F. Koay et al.   Science Immunology

The integrative biology of type 2 diabetes

(2019) Michael Roden et al.   NATURE

Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity

(2019) Zachary J. Ward et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-cell connectomic analysis of adult mammalian lungs

(2019) Micha Sam Brickman Raredon et al.   Science Advances

An Integrated View of Immunometabolism

(2018) Yun Sok Lee et al.   CELL

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

(2018) Jan P. Böttcher et al.   CELL

Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets

(2018) Claire E. Macdougall et al.   Cell Metabolism

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

(2018) David A. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

CD62L Is a Functional and Phenotypic Marker for Circulating Innate Lymphoid Cell Precursors

(2018) Yotam E. Bar-Ephraim et al.   JOURNAL OF IMMUNOLOGY

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

(2017) Yannick Simoni et al.   IMMUNITY

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation

(2017) Yotam E. Bar-Ephraim et al.   Cell Reports

Anti-inflammatory Agents in the Treatment of Diabetes and Its Vascular Complications

(2016) Rena M. Pollack et al.   DIABETES CARE

Adipose-Resident Group 1 Innate Lymphoid Cells Promote Obesity-Associated Insulin Resistance

(2016) Timothy E. O’Sullivan et al.   IMMUNITY

EomeshiNK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation

(2016) Antonia O. Cuff et al.   JOURNAL OF IMMUNOLOGY

Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice

(2016) Jongkil Kim et al.   Molecular Therapy-Nucleic Acids

ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity

(2015) Hadi Maazi et al.   IMMUNITY

Regulation of metabolism by the innate immune system

(2015) Denise E. Lackey et al.   Nature Reviews Endocrinology

The Many Alternative Faces of Macrophage Activation

(2015) David A. Hume   Frontiers in Immunology

Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses

(2014) Nicole Joller et al.   IMMUNITY

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT

(2014) Tim D. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Innate Lymphoid Cells in Human Skin and Blood Demonstrates Increase of NKp44+ ILC3 in Psoriasis

(2013) Federica Villanova et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice

(2012) Robert W. O'Rourke et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets

(2011) K. L. Wong et al.   BLOOD

LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEM

(2011) Hong-Min Kim et al.   FEBS LETTERS

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY