Rapamycin restores peripheral blood flow in aged mice and in mouse models of atherosclerosis and Alzheimer’s disease

Alternate Day Fasting Improves Endothelial Function in Type 2 Diabetic Mice: Role of Adipose-Derived Hormones

(2022) Jian Cui et al.   Frontiers in Cardiovascular Medicine

Dietary Risk Factors and Eating Behaviors in Peripheral Arterial Disease (PAD)

(2022) Andrea Leonardo Cecchini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

mTOR Attenuation with Rapamycin Reverses Neurovascular Uncoupling and Memory Deficits in Mice Modeling Alzheimer's Disease

(2021) Candice E. Van Skike et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms of dietary restriction promoting health and longevity

(2021) Cara L. Green et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Is there any role of intermittent fasting in the prevention and improving clinical outcomes of COVID-19?: intersection between inflammation, mTOR pathway, autophagy and calorie restriction

(2021) Martin Gnoni et al.   VirusDisease

Early Vascular Aging in Children With Tuberous Sclerosis Complex

(2021) Piotr Skrzypczyk et al.   Frontiers in Pediatrics

Nitric Oxide and Endothelial Dysfunction

(2020) Anthony R. Cyr et al.   CRITICAL CARE CLINICS

Exercise training improves vascular function in patients with Alzheimer’s disease

(2020) Anna Pedrinolla et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia

(2020) Priya Balasubramanian et al.   AGEING RESEARCH REVIEWS

Peripheral Artery Disease: Past, Present, and Future

(2019) Umberto Campia et al.   AMERICAN JOURNAL OF MEDICINE

Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans

(2019) Humaira Jamshed et al.   Nutrients

Age-related decline in peripheral vascular health predicts cognitive impairment

(2019) Tamas Csipo et al.   GeroScience

mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging

(2019) Candice E. Van Skike et al.   AGING CELL

Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment

(2019) Ellen Quarles et al.   AGING CELL

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment

(2018) Candice E. Van Skike et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Impact of Nitric Oxide Bioavailability on the Progressive Cerebral and Peripheral Circulatory Impairments During Aging and Alzheimer's Disease

(2018) Massimo Venturelli et al.   Frontiers in Physiology

mTOR drives cerebral blood flow and memory deficits in LDLR−/− mice modeling atherosclerosis and vascular cognitive impairment

(2017) Jordan B Jahrling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanisms and time course of menthol-induced cutaneous vasodilation

(2017) Daniel H. Craighead et al.   MICROVASCULAR RESEARCH

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts

(2016) Ying Ann Chiao et al.   Aging-US

Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer’s disease

(2016) Ai-Ling Lin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Polyphosphate: A Conserved Modifier of Amyloidogenic Processes

(2016) Claudia M. Cremers et al.   MOLECULAR CELL

A Review of the Pathophysiology and Potential Biomarkers for Peripheral Artery Disease

(2015) Smriti Krishna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

(2014) Dao-Fu Dai et al.   AGING CELL

Late-life rapamycin treatment reverses age-related heart dysfunction

(2013) James M. Flynn et al.   AGING CELL

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

(2013) Richard A. Miller et al.   AGING CELL

Chronic Rapamycin Restores Brain Vascular Integrity and Function Through NO Synthase Activation and Improves Memory in Symptomatic Mice Modeling Alzheimer’s Disease

(2013) Ai-Ling Lin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Rapamycin Extends Life and Health in C57BL/6 Mice

(2013) Yiqiang Zhang et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis

(2013) F Gerald R Fowkes et al.   LANCET

Rapamycin slows aging in mice

(2012) John E. Wilkinson et al.   AGING CELL

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

(2012) J. Halloran et al.   NEUROSCIENCE

To screen or not to screen for peripheral arterial disease in subjects aged 80 and over in primary health care: a cross-sectional analysis from the BELFRAIL study

(2011) Stein Bergiers et al.   BMC Family Practice

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone

(2009) Christopher D. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Involvement of Transient Receptor Potential Vanilloid Subtype 1 in Analgesic Action of Methylsalicylate

(2008) T. Ohta et al.   MOLECULAR PHARMACOLOGY