Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value

Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma

(2023) Lipika Goyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

FIGHT-101, a first-in-human study of potent and selective FGFR 1–3 inhibitor pemigatinib in pan-cancer patients with FGF/FGFR alterations and advanced malignancies

(2022) V. Subbiah et al.   ANNALS OF ONCOLOGY

miRNA-381-3p Functions as a Tumor Suppressor to Inhibit Gastric Cancer by Targeting Fibroblast Growth Factor Receptor-2

(2022) Xiang Gao et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

FGF–FGFR signaling promotes the development of invasive cervical cancer

(2022) Duarte Mateus et al.   FEBS Journal

Phase 2 Study of Neoadjuvant FGFR Inhibition and Androgen Deprivation Therapy Prior to Prostatectomy

(2022) Elizabeth Liow et al.   Clinical Genitourinary Cancer

Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review)

(2022) Marsel Khabibov et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Germline Variants in Angiogenesis-Related Genes Contribute to Clinical Outcome in Head and Neck Squamous Cell Carcinoma

(2022) Dorota Butkiewicz et al.   Cancers

Far beyond anti-angiogenesis: Benefits for anti-basicFGF therapy in cancer

(2022) ChunYan Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Elevated Angiogenic Factor Levels After Transarterial Radioembolization for Colorectal Cancer Liver Metastases May Predict a Poor Prognosis

(2022) Çiğdem Soydal et al.   Molecular Imaging and Radionuclide Therapy

Bemarituzumab in patients with FGFR2b-selected gastric or gastro-oesophageal junction adenocarcinoma (FIGHT): a randomised, double-blind, placebo-controlled, phase 2 study

(2022) Zev A Wainberg et al.   LANCET ONCOLOGY

Addressing the Role of Angiogenesis in Patients with Advanced Pancreatic Neuroendocrine Tumors Treated with Everolimus: A Biological Prospective Analysis of Soluble Biomarkers and Clinical Outcomes

(2022) Chiara Alessandra Cella et al.   Cancers

Marine Seagrass Extract of Thalassia testudinum Suppresses Colorectal Tumor Growth, Motility and Angiogenesis by Autophagic Stress and Immunogenic Cell Death Pathways

(2021) Ivones Hernández-Balmaseda et al.   Marine Drugs

Nuclear FGFR1 regulates gene transcription and promotes antiestrogen resistance in ER+ breast cancer

(2021) Alberto Servetto et al.   CLINICAL CANCER RESEARCH

Advances of Fibroblast Growth Factor/Receptor Signaling Pathway in Hepatocellular Carcinoma and its Pharmacotherapeutic Targets

(2021) Haijun Wang et al.   Frontiers in Pharmacology

Role of bFGF in Acquired Resistance upon Anti-VEGF Therapy in Cancer

(2021) Fatema Tuz Zahra et al.   Cancers

Futibatinib, an irreversible FGFR1-4 inhibitor, in patients with advanced solid tumors harboring FGF/FGFR aberrations: a phase I dose-expansion study

(2021) Funda Meric-Bernstam et al.   Cancer Discovery

The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction

(2021) Olga Soriano et al.   Genes

Efficacy of a Novel Oral Chemotherapeutic Agent, TAS-102, Against Human Oral Squamous Cell Carcinoma Cells

(2021) KOJI HARADA et al.   ANTICANCER RESEARCH

ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY

(2021) Danfei Liu et al.   Cell Death & Disease

AZD4547 targets the FGFR/Akt/SOX2 axis to overcome paclitaxel resistance in head and neck cancer

(2021) Abdulmelik Aytatli et al.   CELLULAR ONCOLOGY

Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction

(2021) Aisling B. Heeran et al.   Metabolites

Morin supplementation modulates PERK branch of UPR and mitigates 1,2-dimethylhydrazine-induced angiogenesis and oxidative stress in the colon of experimental rats

(2020) Sharada H. Sharma et al.   TOXICOLOGY MECHANISMS AND METHODS

Dual Vascular Endothelial Growth Factor Receptor and Fibroblast Growth Factor Receptor Inhibition Elicits Antitumor Immunity and Enhances Programmed Cell Death-1 Checkpoint Blockade in Hepatocellular Carcinoma

(2020) Haijing Deng et al.   Liver Cancer

Fibroblast growth factors signaling in bone metastasis

(2020) Estefania Labanca et al.   ENDOCRINE-RELATED CANCER

Expression of pro-angiogenic factors as potential biomarkers in experimental models of colon cancer

(2020) Simona Delle Monache et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Effect of thyroidectomy on circulating angiogenic cytokines in papillary thyroid carcinoma and benign goiter: Potential for new biomarkers?

(2020) Roberto Ria et al.   SURGERY

Maspin suppresses cell invasion and migration in gastric cancer through inhibiting EMT and angiogenesis via ITGB1/FAK pathway

(2020) Ning Wang et al.   Human Cell

The correlation between ultrasonographic features, bFGF, and the local invasiveness of thyroid papillary carcinoma

(2020) Zhi-Ying Jia et al.   MEDICINE

Pomegranate (Punica granatum) Fruit Extract Suppresses Cancer Progression and Tumor Angiogenesis of Pancreatic and Colon Cancer in Chick Chorioallantoic Membrane Model

(2020) Thangirala Sudha et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

FGF Expression in HPV16-positive and -negative SCC After Treatment With Small-molecule Tyrosine Kinase Inhibitors and Everolimus

(2020) LENA HUBER et al.   ANTICANCER RESEARCH

Futibatinib is a novel irreversible FGFR 1-4 inhibitor that shows selective antitumor activity against FGFR-deregulated tumors

(2020) Hiroshi Sootome et al.   CANCER RESEARCH

Extracellular matrix-bound FGF2 mediates estrogen receptor signaling and therapeutic response in breast cancer

(2020) Josh W. DiGiacomo et al.   MOLECULAR CANCER RESEARCH

bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice

(2020) Laura Parma et al.   Scientific Reports

Cell-surface heparan sulfate proteoglycans as multifunctional integrators of signaling in cancer

(2020) Nourhan Hassan et al.   CELLULAR SIGNALLING

Bevacizumab Augments the Antitumor Efficacy of Infigratinib in Hepatocellular Carcinoma

(2020) Thi Bich Uyen Le et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Expression and Prognostic Value of FGF2, FGFR3, and FGFBP1 in Esophageal Squamous Cell Carcinoma

(2020) Wenjing Zhang et al.   Analytical Cellular Pathology

Role of Fibroblast Growth Factors Receptors (FGFRs) in Brain Tumors, Focus on Astrocytoma and Glioblastoma

(2020) Alessio Ardizzone et al.   Cancers

Basic fibroblast growth factor enhances proliferation and hepatocyte growth factor expression of feline mesenchymal stem cells

(2020) Youhei Fujimoto et al.   Regenerative Therapy

TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure

(2019) Maria Kalyukina et al.   ChemMedChem

Effect of Fibroblast Growth Factor-2 and its Receptor Gene Polymorphisms on the Survival of Patients With Hepatitis B Virus-associated Hepatocellular Carcinoma

(2019) SOON SUN KIM et al.   ANTICANCER RESEARCH

Peptide P11 suppresses the growth of human thyroid carcinoma by inhibiting the PI3K/AKT/mTOR signaling pathway

(2019) Dongdong Wu et al.   MOLECULAR BIOLOGY REPORTS

Fibroblast Growth Factor Family in the Progression of Prostate Cancer

(2019) Jun Teishima et al.   Journal of Clinical Medicine

Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology

(2019) Racheal G. Akwii et al.   Cells

RAS in pancreatic cancer

(2019) Simone Lanfredini et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SWOG S1400D (NCT02965378), a Phase II Study of the Fibroblast Growth Factor Receptor Inhibitor AZD4547 in Previously Treated Patients With Fibroblast Growth Factor Pathway–Activated Stage IV Squamous Cell Lung Cancer (Lung-MAP Substudy)

(2019) Charu Aggarwal et al.   Journal of Thoracic Oncology

Circulating pro- and anti-angiogenic factors in multi-stage liver disease and hepatocellular carcinoma progression

(2019) Yu Young Joo et al.   Scientific Reports

Sustained Release of Basic Fibroblast Growth Factor (bFGF) Encapsulated Polycaprolactone (PCL) Microspheres Promote Angiogenesis In Vivo

(2019) Pala Arunkumar et al.   Nanomaterials

Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis

(2019) Jinglin Zhang et al.   Cells

First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant Fibroblast Growth Factor 19 Signaling as a Driver Event in Hepatocellular Carcinoma

(2019) Richard D Kim et al.   Cancer Discovery

Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular Carcinoma

(2019) Megan A. Hatlen et al.   Cancer Discovery

Phase II trial of ponatinib in patients with bevacizumab‐refractory glioblastoma

(2019) Eudocia Q. Lee et al.   Cancer Medicine

Transcription Factor Prospero Homeobox 1 (PROX1) as a Potential Angiogenic Regulator of Follicular Thyroid Cancer Dissemination

(2019) Magdalena Rudzińska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Actionable FGFR1 and BRAF mutations in adult circumscribed gliomas

(2019) Elena Trisolini et al.   JOURNAL OF NEURO-ONCOLOGY

Impact of Breast Cancer Treatment on Employment: Results of a Multicenter Prospective Cohort Study (CANTO)

(2019) Agnes Dumas et al.   JOURNAL OF CLINICAL ONCOLOGY

miR-27b-3p is Involved in Doxorubicin resistance of Human Anaplastic Thyroid Cancer Cells via Targeting PPARγ

(2018) Yuan Xu et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer

(2018) Kevin Shee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer

(2018) Carine Pecqueux et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats

(2018) Dawei Sun et al.   Cell Death & Disease

Phase II Study of Dovitinib in Patients with Castration-Resistant Prostate Cancer (KCSG-GU11-05)

(2018) Yoon Ji Choi et al.   Cancer Research and Treatment

MiR-148b-3p inhibits renal carcinoma cell growth and pro-angiogenic phenotype of endothelial cell potentially by modulating FGF2

(2018) Hui Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

FGF-2 and FGFR-1 might be independent prognostic factors in Oral Tongue Squamous Cell Carcinoma

(2018) Bruno Augusto Linhares Almeida Mariz et al.   HISTOPATHOLOGY

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

Production of bFGF monoclonal antibody and its inhibition of metastasis in Lewis lung carcinoma

(2017) Yanqing Yang et al.   Molecular Medicine Reports

FGF-dependent metabolic control of vascular development

(2017) Pengchun Yu et al.   NATURE

Inflammatory cytokines and angiogenic factors as potential biomarkers in South African pancreatic ductal adenocarcinoma patients: A preliminary report

(2017) Yandiswa Y. Yako et al.   PANCREATOLOGY

Common developmental genome deprogramming in schizophrenia — Role of Integrative Nuclear FGFR1 Signaling (INFS)

(2017) S.T. Narla et al.   SCHIZOPHRENIA RESEARCH

Cancer-associated fibroblasts secrete FGF-1 to promote ovarian proliferation, migration, and invasion through the activation of FGF-1/FGFR4 signaling

(2017) Yuanzhen Sun et al.   TUMOR BIOLOGY

MiR-195 Inhibits Tumor Growth and Metastasis in Papillary Thyroid Carcinoma Cell Lines by Targeting CCND1 and FGF2

(2017) Yali Yin et al.   International Journal of Endocrinology

Basic fibroblast growth factor as a potential biomarker for diagnosing malignant tumor metastasis in women

(2017) Man Liu et al.   Oncology Letters

Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells

(2017) YanFei Wei et al.   Oncotarget

Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells

(2017) Wang Chengye et al.   Oncotarget

HOXB7 promotes tumor progression via bFGF-induced activation of MAPK/ERK pathway and indicated poor prognosis in hepatocellular carcinoma

(2017) Wei-Min Wang et al.   Oncotarget

The molecular mechanisms of chemoresistance in cancers

(2017) Hua-Chuan Zheng   Oncotarget

Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components

(2017) Julia P Steringer et al.   eLife

Peptidomimetic suppresses proliferation and invasion of gastric cancer cells by fibroblast growth factor 2 signaling cascade blockage

(2016) Wulan Li et al.   ANTI-CANCER DRUGS

FGF2 regulates proliferation, migration, and invasion of ECA109 cells through PI3K/Akt signalling pathway in vitro

(2016) Hui Shi et al.   CELL BIOLOGY INTERNATIONAL

Celecoxib suppresses fibroblast growth factor-2 expression in pancreatic ductal adenocarcinoma PANC-1 cells

(2016) Jing Li et al.   ONCOLOGY REPORTS

Quercetin-3-O-glucoside suppresses pancreatic cancer cell migration induced by tumor-deteriorated growth factors in vitro

(2016) JUNGWHOI LEE et al.   ONCOLOGY REPORTS

Blocking the FGF/FGFR system as a ⿿two-compartment⿿ antiangiogenic/antitumor approach in cancer therapy

(2016) Arianna Giacomini et al.   PHARMACOLOGICAL RESEARCH

bFGF Promotes Migration and Induces Cancer-Associated Fibroblast Differentiation of Mouse Bone Mesenchymal Stem Cells to Promote Tumor Growth

(2016) Xue Yang et al.   STEM CELLS AND DEVELOPMENT

Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies

(2016) Mohamed R. Akl et al.   Oncotarget

Prognostic Value of Basic Fibroblast Growth Factor (bFGF) in Lung Cancer: A Systematic Review with Meta-Analysis

(2016) Mingming Hu et al.   PLoS One

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

(2015) Roberto Ronca et al.   CANCER CELL

Fibroblast growth factor family aberrations in cancers: clinical and molecular characteristics

(2015) A Parish et al.   CELL CYCLE

miR-203 inhibition of renal cancer cell proliferation, migration and invasion by targeting of FGF2

(2015) Mingxi Xu et al.   Diagnostic Pathology

Fibroblast growth factor signaling in skeletal development and disease

(2015) David M. Ornitz et al.   GENES & DEVELOPMENT

Effect of recombinant human endostatin on the expression of c-Myc and bFGF in mouse gastric cancer cells

(2015) Z.Y. Guo et al.   GENETICS AND MOLECULAR RESEARCH

Second-line dovitinib (TKI258) in patients with FGFR2-mutated or FGFR2-non-mutated advanced or metastatic endometrial cancer: a non-randomised, open-label, two-group, two-stage, phase 2 study

(2015) Gottfried E Konecny et al.   LANCET ONCOLOGY

Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro

(2015) YANG HU et al.   Molecular Medicine Reports

Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1)

(2015) Christopher Terranova et al.   PLoS One

A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer

(2015) Lei Fan et al.   TUMOR BIOLOGY

FGF2-mediated reciprocal tumor cell-endothelial cell interplay contributes to the growth of chemoresistant cells: a potential mechanism for superficial bladder cancer recurrence

(2015) Yule Chen et al.   TUMOR BIOLOGY

Role of fibroblast growth factor in squamous cell carcinoma of the bladder: Prognostic biomarker and potential therapeutic target

(2015) Ramy F. Youssef et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

The Fibroblast Growth Factor signaling pathway

(2015) David M. Ornitz et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Growth-Factor-Driven Rescue to Receptor Tyrosine Kinase (RTK) Inhibitors through Akt and Erk Phosphorylation in Pediatric Low Grade Astrocytoma and Ependymoma

(2015) Mariska Sie et al.   PLoS One

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor

(2015) Koichi Azuma et al.   Oncotarget

SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer׳s disease induced by amyloid β and excitatory amino acids

(2014) Ryoko Ogino et al.   BRAIN RESEARCH

API5 Confers Tumoral Immune Escape through FGF2-Dependent Cell Survival Pathway

(2014) K. H. Noh et al.   CANCER RESEARCH

Clinical Significance of Fibroblast Growth Factor (FGF) Expression in Colorectal Cancer

(2014) Norie Jibiki et al.   INTERNATIONAL SURGERY

Knockout of Nuclear High Molecular Weight FGF2 Isoforms in Mice Modulates Bone and Phosphate Homeostasis

(2014) Collin Homer-Bouthiette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacillus Calmette-Guérin (BCG) Infection Following Intravesical BCG Administration as Adjunctive Therapy For Bladder Cancer

(2014) María Asunción Pérez-Jacoiste Asín et al.   MEDICINE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clinical application of growth factors and cytokines in wound healing

(2014) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

Prognostic Significance of Targetable Angiogenic and Growth Factors in Patients Undergoing Resection for Gastric and Gastroesophageal Junction Cancers

(2013) Do Joong Park et al.   ANNALS OF SURGICAL ONCOLOGY

The role of basic fibroblast growth factor in glioblastoma multiforme and glioblastoma stem cells and in their in vitro culture

(2013) Elizabeth M. Haley et al.   CANCER LETTERS

Initial Contact of Glioblastoma Cells with Existing Normal Brain Endothelial Cells Strengthen the Barrier Function via Fibroblast Growth Factor 2 Secretion: A New In Vitro Blood–Brain Barrier Model

(2013) Keisuke Toyoda et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

P7 peptides targeting bFGF sensitize colorectal cancer cells to CPT-11

(2013) WU LUO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Fibroblast Growth Factor-2 Signaling in Neurogenesis and Neurodegeneration

(2013) Maya E. Woodbury et al.   Journal of Neuroimmune Pharmacology

Emergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumours

(2013) Brittany C Parker et al.   JOURNAL OF PATHOLOGY

High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer

(2013) Matthias Preusser et al.   LUNG CANCER

DVC1-0101 to Treat Peripheral Arterial Disease: A Phase I/IIa Open-label Dose-escalation Clinical Trial

(2013) Yoshikazu Yonemitsu et al.   MOLECULAR THERAPY

RNA interference-mediated silencing of VEGF and bFGF suppresses endostatin secretion in pancreatic carcinoma cells

(2013) CHANGQING YAN et al.   Oncology Letters

FGF-2 inhibits TNF-α mediated apoptosis through up-regulation of Bcl2-A1 and Bcl-xL in ATDC5 cells

(2012) Hey-Ryun Kim et al.   BMB Reports

Expression, prognostic and predictive impact of VEGF and bFGF in non-small cell lung cancer

(2012) Fadi S. Farhat et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Circulating Angiostatin, bFGF, and Tie2/TEK Levels and Their Prognostic Impact in Bladder Cancer

(2012) Tibor Szarvas et al.   UROLOGY

Toxicarioside A inhibits SGC-7901 proliferation, migration and invasionviaNF-κB/bFGF signaling

(2012) Jun-Li Guo   WORLD JOURNAL OF GASTROENTEROLOGY

FGF Receptor Inhibitors: Role in Cancer Therapy

(2012) Gennaro Daniele et al.   Current Oncology Reports

The tumor microenvironment in prostate cancer: elucidating molecular pathways for therapy development

(2012) Paul G Corn   Cancer Management and Research

Acquired platinum resistance enhances tumour angiogenesis through angiotensin II type 1 receptor in bladder cancer

(2011) N Tanaka et al.   BRITISH JOURNAL OF CANCER

Phase I/II and Pharmacodynamic Study of Dovitinib (TKI258), an Inhibitor of Fibroblast Growth Factor Receptors and VEGF Receptors, in Patients with Advanced Melanoma

(2011) K. B. Kim et al.   CLINICAL CANCER RESEARCH

Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma

(2011) Masanobu Tsubaki et al.   CYTOKINE

TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition

(2011) Takuya Shirakihara et al.   EMBO JOURNAL

A Novel Requirement for Janus Kinases as Mediators of Drug Resistance Induced by Fibroblast Growth Factor-2 in Human Cancer Cells

(2011) Catarina R. Carmo et al.   PLoS One

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Regulation of Tumor Angiogenesis by EZH2

(2010) Chunhua Lu et al.   CANCER CELL

Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma

(2010) A. Dubrovska et al.   CLINICAL CANCER RESEARCH

Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration

(2010) Ye-Rang Yun et al.   Journal of Tissue Engineering

A chemosensitivity test to individualize intravesical treatment for non-muscle-invasive bladder cancer

(2009) Paola Gazzaniga et al.   BJU INTERNATIONAL

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

(2009) Steven M. Pollard et al.   Cell Stem Cell

Loss-of-Function Fibroblast Growth Factor Receptor-2 Mutations in Melanoma

(2009) Michael G. Gartside et al.   MOLECULAR CANCER RESEARCH

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Effect of bFGF on invasion of ovarian cancer cells through the regulation of Ets-1 and urokinase-type plasminogen activator

(2009) Ting Li et al.   PHARMACEUTICAL BIOLOGY

Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer

(2008) C. Behrens et al.   CLINICAL CANCER RESEARCH

Basic fibroblast growth factor-enhanced neurogenesis contributes to cognitive recovery in rats following traumatic brain injury

(2008) Dong Sun et al.   EXPERIMENTAL NEUROLOGY

Novel therapeutic targets in bladder cancer: mutation and expression of FGF receptors

(2008) Margaret A Knowles   Future Oncology

Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

(2008) Liping Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Angiogenesis-Related Genes Regulates Different Steps in the Process of Tumor Growth and Metastasis in Human Urothelial Cell Carcinoma of the Urinary Bladder

(2008) M. Chikazawa et al.   PATHOBIOLOGY

Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting

(2008) Kristian Pietras et al.   PLOS MEDICINE