Actionable FGFR1 and BRAF mutations in adult circumscribed gliomas

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

(2018) Annekathrin Reinhardt et al.   ACTA NEUROPATHOLOGICA

FGFR1actionable mutations, molecular specificities, and outcome of adult midline gliomas

(2018) Alberto Picca et al.   NEUROLOGY

Bevacizumab, irinotecan, temozolomide, tyrosine kinase inhibition, and MEK inhibition are effective against pleomorphic xanthoastrocytoma regardless of V600E status

(2018) Eric M. Thompson et al.   JOURNAL OF NEURO-ONCOLOGY

Targeted MAPK Pathway Inhibitors in Patients With Disseminated Pilocytic Astrocytomas

(2017) Anastasia Drobysheva et al.   Journal of the National Comprehensive Cancer Network

Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors

(2016) Barbara Rivera et al.   ACTA NEUROPATHOLOGICA

BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas

(2016) A. Olow et al.   CLINICAL CANCER RESEARCH

Successful Treatment of a ProgressiveBRAFV600E–Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy

(2016) Eudocia Q. Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas

(2016) Jie Zhang et al.   JOURNAL OF NEURO-ONCOLOGY

KIAA1549

(2015) Aline Paixão Becker et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A comparative analysis of MAPK pathway hallmark alterations in pilocytic astrocytomas: age-related and mutually exclusive

(2015) Benjamin Brokinkel et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

(2013) Christian Koelsche et al.   ACTA NEUROPATHOLOGICA

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

(2013) David T W Jones et al.   NATURE GENETICS

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

MAPK pathway activation in pilocytic astrocytoma

(2011) David T. W. Jones et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma

(2010) Anja E. Eisenhardt et al.   INTERNATIONAL JOURNAL OF CANCER

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

(2009) D T W Jones et al.   ONCOGENE