Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction

Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma

(2019) Amy M. Buckley et al.   CANCER LETTERS

The prognostic role of obesity is independent of sex in cancer patients treated with immune checkpoint inhibitors: A pooled analysis of 4090 cancer patients

(2019) Huilin Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis

(2018) Jennifer L McQuade et al.   LANCET ONCOLOGY

Mast cells participate in chronic low-grade inflammation within adipose tissue

(2018) P. Żelechowska et al.   Obesity Reviews

Serum Levels of Interleukin-13 Increase in Subjects with Insulin Resistance but Do Not Correlate with Markers of Low-Grade Systemic Inflammation

(2018) Camilo P. Martínez-Reyes et al.   Journal of Diabetes Research

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

(2018) Ziming Wang et al.   NATURE MEDICINE

Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes

(2018) Ya-Chin Hou et al.   Journal of Clinical Medicine

Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance

(2017) Emer M. Guinan et al.   SUPPORTIVE CARE IN CANCER

PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity

(2016) J. Incio et al.   CLINICAL CANCER RESEARCH

Body Fatness and Cancer — Viewpoint of the IARC Working Group

(2016) Béatrice Lauby-Secretan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sarcopenia is associated with toxicity in patients undergoing neo-adjuvant chemotherapy for oesophago-gastric cancer

(2015) B.H.L. Tan et al.   EJSO

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

(2015) P Darkhal et al.   INTERNATIONAL JOURNAL OF OBESITY

Current Status of Management of Malignant Disease: Current Management of Esophageal Cancer

(2015) Jonathan Cools-Lartigue et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Systemic Inflammation in Cachexia – Is Tumor Cytokine Expression Profile the Culprit?

(2015) Emidio M. de Matos-Neto et al.   Frontiers in Immunology

Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma

(2014) Niamh Lynam-Lennon et al.   BMC CANCER

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway

(2014) Hyokjoon Kwon et al.   Cell Reports

Establishing computed tomography–defined visceral fat area thresholds for use in obesity-related cancer research

(2013) Suzanne L. Doyle et al.   NUTRITION RESEARCH

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer

(2012) P. van Hagen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue

(2011) J. Lysaght et al.   CANCER LETTERS

Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity

(2011) Olga Gealekman et al.   CIRCULATION

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity

(2010) Regitze Kraunsøe et al.   JOURNAL OF PHYSIOLOGY-LONDON

Release of Inflammatory Mediators by Human Adipose Tissue Is Enhanced in Obesity and Primarily by the Nonfat Cells: A Review

(2010) John N. Fain   MEDIATORS OF INFLAMMATION

Bevacizumab

(2010) F. Kazazi-Hyseni et al.   ONCOLOGIST

Visceral fat area is an independent predictive biomarker of outcome after first-line bevacizumab-based treatment in metastatic colorectal cancer

(2009) B. Guiu et al.   GUT

Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-γ in inflammation in human adipose tissue

(2009) R W O'Rourke et al.   INTERNATIONAL JOURNAL OF OBESITY

Angiogenesis Associated With Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity

(2008) S. Ledoux et al.   DIABETES

Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women

(2008) M Sumarac-Dumanovic et al.   INTERNATIONAL JOURNAL OF OBESITY