Fibroblast Growth Factor Family in the Progression of Prostate Cancer

Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis

(2018) Xiangqi Meng et al.   CANCER LETTERS

Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer

(2018) Junchen Liu et al.   CANCER RESEARCH

βKlotho inhibits androgen/androgen receptor‑associated epithelial‑mesenchymal transition in prostate cancer through inactivation of ERK1/2 signaling

(2018) Zhao Liu et al.   ONCOLOGY REPORTS

FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer

(2018) Carine Pecqueux et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN

(2018) Longjiang Shao et al.   Oncotarget

Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression

(2018) Qianjin Li et al.   NEOPLASIA

Ectopic fibroblast growth factor receptor 1 promotes inflammation by promoting nuclear factor-κB signaling in prostate cancer cells

(2018) Cong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibroblast growth factor modulates mast cell recruitment in a murine model of prostate cancer

(2017) Roberto Ronca et al.   Oncotarget

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

(2015) Roberto Ronca et al.   CANCER CELL

Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression

(2015) Yanqing Huang et al.   International Journal of Biological Sciences

Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment

(2015) Yanqing Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23

(2015) Chiara Degirolamo et al.   NATURE REVIEWS DRUG DISCOVERY

Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients

(2015) J Liu et al.   ONCOGENE

FGF19 promotes progression of prostate cancer

(2015) Hirotaka Nagamatsu et al.   PROSTATE

FGF23 promotes prostate cancer progression

(2015) Shu Feng et al.   Oncotarget

Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells

(2014) KOICHI SHOJI et al.   ONCOLOGY REPORTS

Endocrine Fibroblast Growth Factor FGF19 Promotes Prostate Cancer Progression

(2013) S. Feng et al.   CANCER RESEARCH

Targeting Fibroblast Growth Factor Pathways in Prostate Cancer

(2013) P. G. Corn et al.   CLINICAL CANCER RESEARCH

FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57

(2012) R. Cuevas et al.   CANCER RESEARCH

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

Fibroblast growth factors and their receptors in cancer

(2011) Jørgen Wesche et al.   BIOCHEMICAL JOURNAL

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

(2011) N. Itoh et al.   JOURNAL OF BIOCHEMISTRY

FGFR1 abrogates inhibitory effect of androgen receptor concurrent with induction of androgen-receptor variants in androgen receptor-negative prostate tumor epithelial cells

(2011) Masashi Kobayashi et al.   PROSTATE

Relationship between the localization of fibroblast growth factor 9 in prostate cancer cells and postoperative recurrence

(2011) J Teishima et al.   PROSTATE CANCER AND PROSTATIC DISEASES

FGF signalling in prostate development, tissue homoeostasis and tumorigenesis

(2010) Yongshun Lin et al.   BIOSCIENCE REPORTS

Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas

(2009) Chien-Kai Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Fibroblast growth factor-9 inhibits astrocyte differentiation of adult mouse neural progenitor cells

(2009) Maggie Lum et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix

(2009) J. Kalinina et al.   MOLECULAR AND CELLULAR BIOLOGY

FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

(2009) Masayo Harada et al.   NATURE GENETICS

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating  -Catenin Signaling

(2008) R. Pai et al.   CANCER RESEARCH

Role of epithelial cell fibroblast growth factor receptor substrate 2  in prostate development, regeneration and tumorigenesis

(2008) Y. Zhang et al.   DEVELOPMENT

Cellular Signaling by Fibroblast Growth Factors (FGFs) and Their Receptors (FGFRs) in Male Reproduction

(2008) Leanne M. Cotton et al.   ENDOCRINE REVIEWS

Androgen receptor–negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms

(2008) Zhi Gang Li et al.   JOURNAL OF CLINICAL INVESTIGATION