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Title
Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis
Authors
Keywords
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Journal
Cells
Volume 8, Issue 6, Pages 637
Publisher
MDPI AG
Online
2019-06-25
DOI
10.3390/cells8060637
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Related references
Note: Only part of the references are listed.- Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins
- (2019) Latko et al. Cells
- Future applications of FGF/FGFR inhibitors in cancer
- (2018) Gaia Cristina Ghedini et al. Expert Review of Anticancer Therapy
- FGF Family: From Drug Development to Clinical Application
- (2018) Qi Hui et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- FGFR2 amplification is predictive of sensitivity to regorafenib in gastric and colorectal cancers in vitro
- (2018) Yongjun Cha et al. Molecular Oncology
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p
- (2018) Jinglin Zhang et al. ONCOGENE
- In situ analysis of FGFR2 mRNA and comparison with FGFR2 gene copy number by dual-color in situ hybridization in a large cohort of gastric cancer patients
- (2017) Yasutoshi Kuboki et al. Gastric Cancer
- FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1
- (2017) Tingting Huang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (PRN1371) for the Treatment of Solid Tumors
- (2017) Ken A. Brameld et al. JOURNAL OF MEDICINAL CHEMISTRY
- Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases
- (2017) Frank Hilberg et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3β
- (2017) Wen Min Lau et al. MOLECULAR CANCER THERAPEUTICS
- FGF-dependent metabolic control of vascular development
- (2017) Pengchun Yu et al. NATURE
- TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis
- (2017) Y Zhou et al. ONCOGENE
- A Phase 1 Study of LY2874455, an Oral Selective pan-FGFR Inhibitor, in Patients with Advanced Cancer
- (2017) Michael Michael et al. Targeted Oncology
- Antitumor Effect of AZD4547 in a Fibroblast Growth Factor Receptor 2–Amplified Gastric Cancer Patient–Derived Cell Model
- (2017) Jiryeon Jang et al. Translational Oncology
- Different clinical significance of FGFR1–4 expression between diffuse-type and intestinal-type gastric cancer
- (2017) Mikito Inokuchi et al. World Journal of Surgical Oncology
- Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion
- (2017) Sun Young Kim et al. Oncotarget
- Yes-Associated Protein 1 Promotes Adenocarcinoma Growth and Metastasis through Activation of the Receptor Tyrosine Kinase Axl
- (2017) Z-L. Cui et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Preclinical Efficacy of the Auristatin-Based Antibody–Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors
- (2016) Anette Sommer et al. CANCER RESEARCH
- Targeting the fibroblast growth factor receptor family in cancer
- (2016) Niamh Hallinan et al. CANCER TREATMENT REVIEWS
- Molecular Modeling, de novo Design and Synthesis of a Novel, Extracellular Binding Fibroblast Growth Factor Receptor 2 Inhibitor Alofanib (RPT835)
- (2016) Ilya Tsimafeyeu et al. Medicinal Chemistry
- FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival
- (2016) Soomin Ahn et al. MODERN PATHOLOGY
- Therapeutics Targeting FGF Signaling Network in Human Diseases
- (2016) Masaru Katoh TRENDS IN PHARMACOLOGICAL SCIENCES
- Emerging role of Hippo pathway in gastric and other gastrointestinal cancers
- (2016) Wei Kang WORLD JOURNAL OF GASTROENTEROLOGY
- High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial
- (2016) A. Pearson et al. Cancer Discovery
- The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer
- (2016) Chuanli Ren et al. Oncotarget
- Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation
- (2016) Terence G. Hall et al. PLoS One
- FGFR2 Assessment in Gastric Cancer Using Quantitative Real-Time Polymerase Chain Reaction, Fluorescent In Situ Hybridization, and Immunohistochemistry
- (2015) Young Soo Park et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications
- (2015) Teresa Helsten et al. CANCER AND METASTASIS REVIEWS
- Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy
- (2015) Roberto Ronca et al. CANCER CELL
- HER-2-induced PI3K signaling pathway was involved in the pathogenesis of gastric cancer
- (2015) Y F Fu et al. CANCER GENE THERAPY
- The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing
- (2015) T. Helsten et al. CLINICAL CANCER RESEARCH
- Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization
- (2015) Akishi Ooi et al. MODERN PATHOLOGY
- Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
- (2015) Razvan Cristescu et al. NATURE MEDICINE
- Expression of Fibroblast Growth Factor 10 Is Correlated with Poor Prognosis in Gastric Adenocarcinoma
- (2015) Qinli Sun et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy
- (2015) Ismael Riquelme et al. Oncotarget
- Heparan Sulfate Proteoglycans Regulate Fgf Signaling and Cell Polarity during Collective Cell Migration
- (2015) Marina Venero Galanternik et al. Cell Reports
- Hereditary Diffuse Gastric Cancer Syndrome
- (2015) Samantha Hansford et al. JAMA Oncology
- Twist1 correlates with poor differentiation and progression in gastric adenocarcinomaviaelevation of FGFR2 expression
- (2015) Dong-Yuan Zhu WORLD JOURNAL OF GASTROENTEROLOGY
- Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer
- (2015) Jinjia Chang et al. Oncotarget
- FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study
- (2014) X Su et al. BRITISH JOURNAL OF CANCER
- HER2, MET and FGFR2 oncogenic driver alterations define distinct molecular segments for targeted therapies in gastric carcinoma
- (2014) Y J Liu et al. BRITISH JOURNAL OF CANCER
- Mutually exclusive FGFR2, HER2, and KRAS gene amplifications in gastric cancer revealed by multicolour FISH
- (2014) Kakoli Das et al. CANCER LETTERS
- Epithelial–mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells
- (2014) Paulina Grygielewicz et al. Gastric Cancer
- Clinical Significance of Fibroblast Growth Factor (FGF) Expression in Colorectal Cancer
- (2014) Norie Jibiki et al. INTERNATIONAL SURGERY
- Comprehensive molecular characterization of gastric adenocarcinoma
- (2014) Adam J. Bass et al. NATURE
- FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547
- (2013) L. Xie et al. CLINICAL CANCER RESEARCH
- FGF Receptors: Cancer Biology and Therapeutics
- (2013) Masaru Katoh et al. MEDICINAL RESEARCH REVIEWS
- S49076 Is a Novel Kinase Inhibitor of MET, AXL, and FGFR with Strong Preclinical Activity Alone and in Association with Bevacizumab
- (2013) M. F. Burbridge et al. MOLECULAR CANCER THERAPEUTICS
- Exploring mechanisms of FGF signalling through the lens of structural biology
- (2013) Regina Goetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Fibroblast Growth Factor Receptor Inhibitors as a Cancer Treatment: From a Biologic Rationale to Medical Perspectives
- (2013) Maria Vittoria Dieci et al. Cancer Discovery
- FGFR2 gene amplification and clinicopathological features in gastric cancer
- (2012) K Matsumoto et al. BRITISH JOURNAL OF CANCER
- A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
- (2012) Niantao Deng et al. GUT
- Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma
- (2012) Eun-Jung Jung et al. HUMAN PATHOLOGY
- Ponatinib (AP24534), a Multitargeted Pan-FGFR Inhibitor with Activity in Multiple FGFR-Amplified or Mutated Cancer Models
- (2012) J. M. Gozgit et al. MOLECULAR CANCER THERAPEUTICS
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease
- (2011) N. Itoh et al. JOURNAL OF BIOCHEMISTRY
- Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
- (2010) J. H. Dey et al. CANCER RESEARCH
- Signal Transducers and Activators of Transcription-3 Binding to the Fibroblast Growth Factor Receptor Is Activated by Receptor Amplification
- (2010) A. A. Dudka et al. CANCER RESEARCH
- Biology of FGFRL1, the fifth fibroblast growth factor receptor
- (2010) Beat Trueb CELLULAR AND MOLECULAR LIFE SCIENCES
- Monoclonal Antibodies to Fibroblast Growth Factor Receptor 2 Effectively Inhibit Growth of Gastric Tumor Xenografts
- (2010) W.-m. Zhao et al. CLINICAL CANCER RESEARCH
- Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition
- (2010) Simona Corso et al. Molecular Cancer
- Roles of Fibroblast Growth Factor Receptors in Carcinogenesis
- (2010) E. M. Haugsten et al. MOLECULAR CANCER RESEARCH
- The Role of Fibroblast Growth Factors in Tumor Growth
- (2009) M. Korc et al. CURRENT CANCER DRUG TARGETS
- The FGF family: biology, pathophysiology and therapy
- (2009) Andrew Beenken et al. NATURE REVIEWS DRUG DISCOVERY
- Crosstalk of hedgehog and Wnt pathways in gastric cancer
- (2008) Kosuke Yanai et al. CANCER LETTERS
- Fibroblast Growth Factor Receptor 1 (FGFR1) Tyrosine Phosphorylation Regulates Binding of FGFR Substrate 2α (FRS2α) But Not FRS2β to the Receptor
- (2007) Yongyou Zhang et al. MOLECULAR ENDOCRINOLOGY
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