Exogenous lactate augments exercise-induced improvement in memory but not in hippocampal neurogenesis

Exercise type influences the effect of an acute bout of exercise on hippocampal neuronal activation in mice

(2022) Ryuki Tsuchida et al.   NEUROSCIENCE LETTERS

Elevated Lactate by High-Intensity Interval Training Regulates the Hippocampal BDNF Expression and the Mitochondrial Quality Control System

(2021) Jingyun Hu et al.   Frontiers in Physiology

Adult hippocampal neurogenesis in aging and Alzheimer's disease

(2021) Kelsey R. Babcock et al.   Stem Cell Reports

L-lactate exerts a pro-proliferative effect on adult hippocampal precursor cells in vitro

(2021) Alexandra Pötzsch et al.   iScience

Mini Review: The Relationship between Energy Status and Adult Hippocampal Neurogenesis

(2021) Taylor Landry et al.   NEUROSCIENCE LETTERS

Exercise-Induced Lactate Release Mediates Mitochondrial Biogenesis in the Hippocampus of Mice via Monocarboxylate Transporters

(2021) Jonghyuk Park et al.   Frontiers in Physiology

Acute Administration of Exogenous Lactate Increases Carbohydrate Metabolism during Exercise in Mice

(2021) Inkwon Jang et al.   Metabolites

Inhibition of Androgen Receptor Decreases Fat Metabolism by Decreasing Carnitine Palmitoyltransferase I Levels in Skeletal Muscles of Trained Mice

(2020) Jisu Kim et al.   FASEB JOURNAL

Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

(2020) Patrick Müller et al.   Journal of Clinical Medicine

From Obesity to Hippocampal Neurodegeneration: Pathogenesis and Non-Pharmacological Interventions

(2020) Thomas Ho-yin Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Physical activity and muscle–brain crosstalk

(2019) Bente Klarlund Pedersen   Nature Reviews Endocrinology

L-Lactate Promotes Adult Hippocampal Neurogenesis

(2019) Yaeli Lev-Vachnish et al.   Frontiers in Neuroscience

The role of adult hippocampal neurogenesis in brain health and disease

(2018) Tomohisa Toda et al.   MOLECULAR PSYCHIATRY

Lactate in the brain: from metabolic end-product to signalling molecule

(2018) Pierre J. Magistretti et al.   NATURE REVIEWS NEUROSCIENCE

Exercise-Mediated Neurogenesis in the Hippocampus via BDNF

(2018) Patrick Z. Liu et al.   Frontiers in Neuroscience

Differential Effects of Extended Exercise and Memantine Treatment on Adult Neurogenesis in Male and Female Rats

(2018) Shaina P. Cahill et al.   NEUROSCIENCE

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Endocrine Crosstalk Between Skeletal Muscle and the Brain

(2018) Julien Delezie et al.   Frontiers in Neurology

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

L-Lactate Regulates the Expression of Synaptic Plasticity and Neuroprotection Genes in Cortical Neurons: A Transcriptome Analysis

(2018) Michael B. Margineanu et al.   Frontiers in Molecular Neuroscience

Glucose feeds the TCA cycle via circulating lactate

(2017) Sheng Hui et al.   NATURE

Intense Exercise Promotes Adult Hippocampal Neurogenesis But Not Spatial Discrimination

(2017) Ji H. So et al.   Frontiers in Cellular Neuroscience

Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1

(2017) Cecilie Morland et al.   Nature Communications

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

(2017) Jong Whi Kim et al.   NEURAL PLASTICITY

Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review

(2015) Thierry Paillard et al.   Journal of Clinical Neurology

Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?

(2015) Mohammad Jodeiri Farshbaf et al.   NEUROMOLECULAR MEDICINE

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

Evaluation of the Lactate Threshold of Rats Using External Jugular Vein Catheterization

(2013) Wakako Tsumiyama et al.   Journal of Physical Therapy Science

Daily exercise improves memory, stimulates hippocampal neurogenesis and modulates immune and neuroimmune cytokines in aging rats

(2012) Rachel B. Speisman et al.   BRAIN BEHAVIOR AND IMMUNITY

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

Combined Exercise and Insulin-Like Growth Factor-1 Supplementation Induces Neurogenesis in Old Rats, but Do Not Attenuate Age-Associated DNA Damage

(2011) Erika Koltai et al.   REJUVENATION RESEARCH

A Distinctive layering pattern of mouse dentate granule cells is generated by developmental and adult neurogenesis

(2010) Emily A. Mathews et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour

(2010) María LLorens-Martín et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Blood Lactate is an Important Energy Source for the Human Brain

(2009) Gerrit van Hall et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM