The role of hepatokines in NAFLD

Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study

(2022) Susan Martin et al.   DIABETES CARE

Non-Alcoholic Steatohepatitis (NASH) and Organokines: What Is Now and What Will Be in the Future

(2022) João Paulo Margiotti dos Santos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A global view of the interplay between non-alcoholic fatty liver disease and diabetes

(2022) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

(2022) Sakie Katsumura et al.   Cell Metabolism

Exerkines in health, resilience and disease

(2022) Lisa S. Chow et al.   Nature Reviews Endocrinology

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

(2022) Gretchen Wolff et al.   Molecular Metabolism

Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

(2022) Daniel Q. Huang et al.   Cell Metabolism

Fat-distribution Patterns and Future Type-2 Diabetes

(2022) Hajime Yamazaki et al.   DIABETES

Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals

(2022) Alessandro Mantovani et al.   GUT

Associations between Circulating SELENOP Level and Disorders of Glucose and Lipid Metabolism: A Meta-Analysis

(2022) Ruirui Yu et al.   Antioxidants

Sex hormone binding globulin as a potential drug candidate for liver-related metabolic disorders treatment

(2022) Nabila Bourebaba et al.   BIOMEDICINE & PHARMACOTHERAPY

Multiomics study of nonalcoholic fatty liver disease

(2022) Gardar Sveinbjornsson et al.   NATURE GENETICS

Microbiome-derived ethanol in nonalcoholic fatty liver disease

(2022) Abraham S. Meijnikman et al.   NATURE MEDICINE

The Stress-Responsive microRNA-34a Alters Insulin Signaling and Actions in Adipocytes through Induction of the Tyrosine Phosphatase PTP1B

(2022) Pierre-Jean Cornejo et al.   Cells

Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

(2021) Robert Wagner et al.   NATURE MEDICINE

Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease

(2021) Oveis Jamialahmadi et al.   GASTROENTEROLOGY

Non-alcoholic fatty liver disease and increased risk of incident extrahepatic cancers: a meta-analysis of observational cohort studies

(2021) Alessandro Mantovani et al.   GUT

Clusterin and Its Role in Insulin Resistance and the Cardiometabolic Syndrome

(2021) Jennifer Wittwer et al.   Frontiers in Immunology

The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells

(2021) Felicia Gerst et al.   DIABETOLOGIA

Non-alcoholic fatty liver disease

(2021) Elizabeth E Powell et al.   LANCET

The complex link between NAFLD and type 2 diabetes mellitus — mechanisms and treatments

(2021) Giovanni Targher et al.   Nature Reviews Gastroenterology & Hepatology

FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

(2021) Oliver Stöhr et al.   Cell Reports

Sex Hormone Binding Globulin (SHBG) Mitigates ER Stress in Hepatocytes In Vitro and Ex Vivo

(2021) Katarzyna Kornicka-Garbowska et al.   Cells

Non-alcoholic fatty liver disease: a multisystem disease requiring a multidisciplinary and holistic approach

(2021) Giovanni Targher et al.   Lancet Gastroenterology & Hepatology

Serum Tsukushi levels are elevated in newly diagnosed type 2 diabetic patients

(2021) Yan-Yan Li et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in obese adults with modest hypertriglyceridemia

(2021) Daniel J Rader et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Circulating angiopoietin-like proteins in metabolic-associated fatty liver disease: a systematic review and meta-analysis

(2021) Yani Ke et al.   Lipids in Health and Disease

Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue

(2021) Anastasia Georgiadi et al.   Nature Communications

Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis

(2021) Alessandro Mantovani et al.   Lancet Gastroenterology & Hepatology

Cardiometabolic Health Outcomes Associated With Discordant Visceral and Liver Fat Phenotypes: Insights From the Dallas Heart Study and UK Biobank

(2021) Sanaa Tejani et al.   MAYO CLINIC PROCEEDINGS

Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease

(2021) Arun J. Sanyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Elevated circulating follistatin associates with an increased risk of type 2 diabetes

(2021) Chuanyan Wu et al.   Nature Communications

Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study

(2021) Nooshin Ghodsian et al.   Nutrients

Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism

(2021) Tae Hyun Kim et al.   Biomedicines

Newly discovered endocrine functions of the liver

(2021) Jane Rhyu et al.   World Journal of Hepatology

Lipodystrophic Nonalcoholic Fatty Liver Disease Induced by Immune Checkpoint Blockade

(2020) Thomas Eigentler et al.   ANNALS OF INTERNAL MEDICINE

Leveraging Human Genetics to Identify Potential New Treatments for Fatty Liver Disease

(2020) Stefano Romeo et al.   Cell Metabolism

Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes

(2020) Jonathan R. Davey et al.   FASEB JOURNAL

Liver governs adipose remodelling via extracellular vesicles in response to lipid overload

(2020) Yue Zhao et al.   Nature Communications

Muscle-organ crosstalk: the emerging roles of myokines

(2020) Mai Charlotte Krogh Severinsen et al.   ENDOCRINE REVIEWS

Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping

(2020) Zhipeng Liu et al.   JOURNAL OF HEPATOLOGY

Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

(2020) Ji A Seo et al.   Nature Communications

Fetuin-A and Fetuin-B in Non-Alcoholic Fatty Liver Disease: A Meta-Analysis and Meta-Regression

(2020) Xiongfeng Pan et al.   International Journal of Environmental Research and Public Health

Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet–induced obesity

(2020) Ruhang Tang et al.   Science Advances

A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis

(2020) Tae Gyu Oh et al.   Cell Metabolism

FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes

(2020) Gema Frühbeck et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Causes, consequences, and treatment of metabolically unhealthy fat distribution

(2020) Norbert Stefan   Lancet Diabetes & Endocrinology

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study

(2020) Stephen A Harrison et al.   Lancet Gastroenterology & Hepatology

Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia

(2020) Daniel Gaudet et al.   EUROPEAN HEART JOURNAL

Non-alcoholic fatty liver disease and risk of incident diabetes mellitus: an updated meta-analysis of 501 022 adult individuals

(2020) Alessandro Mantovani et al.   GUT

SeP is elevated in NAFLD and participates in NAFLD pathogenesis through AMPK/ACC pathway

(2020) Yi Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control

(2020) Magdalene K. Montgomery et al.   Science Translational Medicine

Clusterin overexpression protects against western diet-induced obesity and NAFLD

(2020) Jin-Sung Park et al.   Scientific Reports

Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease

(2020) Kasper W. ter Horst et al.   DIABETES CARE

Interplay between Oxidative Stress and Metabolic Derangements in Non-Alcoholic Fatty Liver Disease: The Role of Selenoprotein P

(2020) Gian Paolo Caviglia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hepatokines and metabolism: Deciphering communication from the liver

(2020) Sharon O. Jensen-Cody et al.   Molecular Metabolism

Gut microbial metabolites in obesity, NAFLD and T2DM

(2019) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Adipogenesis and metabolic health

(2019) Alexandra L. Ghaben et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Specificity, versatility, and control of TGF-β family signaling

(2019) Rik Derynck et al.   Science Signaling

A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

(2019) Steven A. Kliewer et al.   Cell Metabolism

The liver as an endocrine organ - linking NAFLD and insulin resistance

(2019) Matthew J Watt et al.   ENDOCRINE REVIEWS

Genome-wide association study of breakfast skipping links clock regulation with food timing

(2019) Hassan S Dashti et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Global Epidemiology of NAFLD and NASH in Patients with type 2 diabetes: A Systematic Review and Meta-analysis

(2019) Zobair M. Younossi et al.   JOURNAL OF HEPATOLOGY

LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

(2019) Meng Xu et al.   CELL

Exosomal microRNA-122 mediates obesity-related cardiomyopathy through suppressing mitochondrial ADP-ribosylation factor-like 2

(2019) Yongshun Wang et al.   CLINICAL SCIENCE

Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome

(2019) C. Ronald Kahn et al.   JOURNAL OF CLINICAL INVESTIGATION

What lipodystrophies teach us about the metabolic syndrome

(2019) Jake P. Mann et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality

(2019) Martijn C. G. J. Brouwers et al.   DIABETOLOGIA

Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides

(2019) Varman T. Samuel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease

(2019) Gordon I. Smith et al.   JOURNAL OF CLINICAL INVESTIGATION

The integrative biology of type 2 diabetes

(2019) Michael Roden et al.   NATURE

The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans

(2018) Andreas Peter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Natural History of Nonalcoholic Fatty Liver Disease—An Evolving View

(2018) Christina C. Lindenmeyer et al.   Clinics in Liver Disease

Hepatic F-Box Protein FBXW7 Maintains Glucose Homeostasis Through Degradation of Fetuin-A

(2018) Jiejie Zhao et al.   DIABETES

Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis

(2018) Janine Kröger et al.   DIABETES

Hypertension, diabetes, atherosclerosis and NASH: Cause or consequence?

(2018) Amedeo Lonardo et al.   JOURNAL OF HEPATOLOGY

LECT2 promotes inflammation and insulin resistance in adipocytes via P38 pathways

(2018) Tae Woo Jung et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Hyperlipidemia-induced hepassocin in the liver contributes to insulin resistance in skeletal muscle

(2018) Tae Woo Jung et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith–Wiedemann syndrome: an international consensus statement

(2018) Frédéric Brioude et al.   Nature Reviews Endocrinology

Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment

(2018) Jonathan Pearson-Stuttard et al.   Lancet Diabetes & Endocrinology

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

(2018) Emma Ahlqvist et al.   Lancet Diabetes & Endocrinology

Metabolic profiling of follistatin overexpression: a novel therapeutic strategy for metabolic diseases

(2018) Rajan Singh et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Publisher Correction: Inactivating hepatic follistatin alleviates hyperglycemia

(2018) Rongya Tao et al.   NATURE MEDICINE

Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies

(2018) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension

(2018) Yingjie Ji et al.   DIABETES

Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial

(2018) Arun Sanyal et al.   LANCET

Fibroblast Growth Factor 21—Metabolic Role in Mice and Men

(2017) Harald Staiger et al.   ENDOCRINE REVIEWS

Modulation of SHBG binding to testosterone and estradiol by sex and morbid obesity

(2017) María del Mar Grasa et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues

(2017) Chofit Chai et al.   GASTROENTEROLOGY

The Hepatic Protection Effects of Hepassocin in Hyperglycemic Crisis

(2017) Horng-Yih Ou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2017) Emmanuela Gakidou et al.   LANCET

Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance

(2017) Ruth C. R. Meex et al.   Nature Reviews Endocrinology

Increasing Lipolysis and Reducing Atherosclerosis

(2017) Alan R. Tall   NEW ENGLAND JOURNAL OF MEDICINE

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

(2017) Mark J. Graham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia

(2017) Kumpei Tanisawa et al.   PLoS One

Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

(2017) Yuichiro Mita et al.   Nature Communications

Association of leukocyte cell-derived chemotaxin 2 (LECT2) with NAFLD, metabolic syndrome, and atherosclerosis

(2017) Hye Jin Yoo et al.   PLoS One

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

(2016) Saswata Talukdar et al.   Cell Metabolism

A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes

(2016) Hung-Tsung Wu et al.   DIABETOLOGIA

Lipodystrophy Syndromes

(2016) Iram Hussain et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin Ratio

(2016) Jakob S. Hansen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications

(2016) Sven M. Francque et al.   JOURNAL OF HEPATOLOGY

Adipose tissue regulates insulin sensitivity: role of adipogenesis,de novolipogenesis and novel lipids

(2016) U. Smith et al.   JOURNAL OF INTERNAL MEDICINE

Circulating follistatin in relation to energy metabolism

(2016) Jakob Schiøler Hansen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

(2016) Luca A Lotta et al.   NATURE GENETICS

Control of diabetic hyperglycaemia and insulin resistance through TSC22D4

(2016) Bilgen Ekim Üstünel et al.   Nature Communications

Phenotypes of prediabetes and stratification of cardiometabolic risk

(2016) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Fetuin-A and risk of coronary heart disease: A Mendelian randomization analysis and a pooled analysis of AHSG genetic variants in 7 prospective studies

(2015) Lars E. Laugsand et al.   ATHEROSCLEROSIS

Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism

(2015) Ruth C. Meex et al.   Cell Metabolism

Hepatokines: unlocking the multi-organ network in metabolic diseases

(2015) Alison Iroz et al.   DIABETOLOGIA

Novel insights in SHBG regulation and clinical implications

(2015) Rafael Simó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

LECT2 Functions as a Hepatokine That Links Obesity to Skeletal Muscle Insulin Resistance

(2014) Fei Lan et al.   DIABETES

Biology of upper-body and lower-body adipose tissue—link to whole-body phenotypes

(2014) Fredrik Karpe et al.   Nature Reviews Endocrinology

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

(2014) Gerald I. Shulman   NEW ENGLAND JOURNAL OF MEDICINE

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Impact of the Adipokine Adiponectin and the Hepatokine Fetuin-A on the Development of Type 2 Diabetes: Prospective Cohort- and Cross-Sectional Phenotyping Studies

(2014) Norbert Stefan et al.   PLoS One

Direct Inhibitory Effects of Pioglitazone on Hepatic Fetuin-A Expression

(2014) Akinobu Ochi et al.   PLoS One

Mechanisms and Metabolic Implications of Regional Differences among Fat Depots

(2013) Tamara Tchkonia et al.   Cell Metabolism

The Effects of LY2405319, an FGF21 Analog, in Obese Human Subjects with Type 2 Diabetes

(2013) Gregory Gaich et al.   Cell Metabolism

Genetically Elevated Fetuin-A Levels, Fasting Glucose Levels, and Risk of Type 2 Diabetes: The Cardiovascular Health Study

(2013) M. K. Jensen et al.   DIABETES CARE

Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics

(2013) Jacklyn N. Hellwege et al.   GENE

Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes

(2013) Andreas L. Birkenfeld et al.   HEPATOLOGY

Measures of Adiposity and Fat Distribution and Risk of Diabetes

(2013) Norbert Stefan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Measures of Adiposity and Fat Distribution and Risk of Diabetes—Reply

(2013) Ian J. Neeland et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The role of Hepassocin in the development of non-alcoholic fatty liver disease

(2013) Hung-Tsung Wu et al.   JOURNAL OF HEPATOLOGY

AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P in HepG2 hepatocytes

(2013) Tae Woo Jung et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Circulating fetuin-A and free fatty acids interact to predict insulin resistance in humans

(2013) Norbert Stefan et al.   NATURE MEDICINE

The role of hepatokines in metabolism

(2013) Norbert Stefan et al.   Nature Reviews Endocrinology

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Increased Selenoprotein P Levels in Subjects with Visceral Obesity and Nonalcoholic Fatty Liver Disease

(2013) Hae Yoon Choi et al.   Diabetes & Metabolism Journal

Association of Fetuin-A With Incident Diabetes Mellitus in Community-Living Older Adults

(2012) Joachim H. Ix et al.   CIRCULATION

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

IL1β Down-regulation of Sex Hormone-Binding Globulin Production by Decreasing HNF-4α Via MEK-1/2 and JNK MAPK Pathways

(2012) Rafael Simó et al.   MOLECULAR ENDOCRINOLOGY

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

Fetuin-A: the missing link in lipid-induced inflammation

(2012) Jan Heinrichsdorff et al.   NATURE MEDICINE

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Potential Role of Tumor Necrosis Factor-  in Downregulating Sex Hormone-Binding Globulin

(2011) R. Simo et al.   DIABETES

The Metabolically Benign and Malignant Fatty Liver

(2011) N. Stefan et al.   DIABETES

Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease

(2011) Romina Lomonaco et al.   HEPATOLOGY

High Glucose Induces Transactivation of the .ALPHA.2-HS Glycoprotein Gene Through the ERK1/2 Signaling Pathway

(2011) Hiroshi Takata et al.   Journal of Atherosclerosis and Thrombosis

Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis

(2011) S. J. Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sex hormone-binding globulin and type 2 diabetes mellitus

(2011) Trang N. Le et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

NF-κB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance

(2010) Suman Dasgupta et al.   BIOCHEMICAL JOURNAL

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

Relationships of Circulating Sex Hormone-Binding Globulin With Metabolic Traits in Humans

(2010) A. Peter et al.   DIABETES

Exercise Induces a Marked Increase in Plasma Follistatin: Evidence That Follistatin Is a Contraction-Induced Hepatokine

(2010) Jakob Hansen et al.   ENDOCRINOLOGY

Emerging roles for the TGFβ family in pancreatic β-cell homeostasis

(2010) Melissa L. Brown et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

(2009) Eva Fisher et al.   Circulation-Cardiovascular Genetics

Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance

(2009) Yusuf Yilmaz et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Recombinant human hepassocin stimulates proliferation of hepatocytes in vivo and improves survival in rats with fulminant hepatic failure

(2009) C. Y. Li et al.   GUT

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

(2009) John R.B. Perry et al.   HUMAN MOLECULAR GENETICS

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men

(2009) Eric L. Ding et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Characterization of Metabolically Benign Obesity in Humans

(2008) Norbert Stefan   ARCHIVES OF INTERNAL MEDICINE

Plasma Fetuin-A Levels and the Risk of Myocardial Infarction and Ischemic Stroke

(2008) Cornelia Weikert et al.   CIRCULATION

Plasma Fetuin-A Levels and the Risk of Type 2 Diabetes

(2008) N. Stefan et al.   DIABETES

Causes and Metabolic Consequences of Fatty Liver

(2008) Norbert Stefan et al.   ENDOCRINE REVIEWS

Fetuin-A and Incident Diabetes Mellitus in Older Persons

(2008) Joachim H. Ix   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fetuin-A and Its Relation to Metabolic Syndrome and Fatty Liver Disease in Obese Children Before and After Weight Loss

(2008) Thomas Reinehr et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of pioglitazone on serum fetuin-A levels in patients with type 2 diabetes mellitus

(2008) Katsuhito Mori et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS