Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue

BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors without causing classical receptor desensitization

(2019) Saori Mukaida et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Genetic basis of functional variability in adhesion G protein-coupled receptors

(2019) Alexander Bernd Knierim et al.   Scientific Reports

Fibronectin Type III Domain Containing 4 attenuates hyperlipidemia-induced insulin resistance via suppression of inflammation and ER stress through HO-1 expression in adipocytes

(2018) Wonjae Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GPCR desensitization: Acute and prolonged phases

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FNDC4 Inhibits RANKL-Induced Osteoclast Formation by Suppressing NF-κB Activation and CXCL10 Expression

(2018) Zheng-tao Lv et al.   Biomed Research International

VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans

(2018) Rita Schüler et al.   Molecular Metabolism

Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance

(2017) Ruth C. R. Meex et al.   Nature Reviews Endocrinology

G Protein–Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus

(2017) Darren M. Riddy et al.   PHARMACOLOGICAL REVIEWS

Lsd1 prevents age-programed loss of beige adipocytes

(2017) Delphine Duteil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes

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Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis of screening tests and interventions

(2017) Eleanor Barry et al.   BMJ-British Medical Journal

Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis of screening tests and interventions

(2017) Eleanor Barry et al.   BMJ-British Medical Journal

High‐Saturated‐Fat Diet Increases Circulating Angiotensin‐Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient‐Dependent Increases of Blood Pressure

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Heritability and responses to high fat diet of plasma lipidomics in a twin study

(2017) Turid Frahnow et al.   Scientific Reports

Bone morphogenetic protein 2 (BMP2 ) may contribute to partition of energy storage into visceral and subcutaneous fat depots

(2016) Esther Guiu-Jurado et al.   Obesity

FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice

(2016) Madeleen Bosma et al.   Nature Communications

Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss

(2016) J. Schmitz et al.   Molecular Metabolism

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

(2015) Aimo Kannt et al.   DIABETOLOGIA

Selective Insulin Resistance in Adipocytes

(2015) Shi-Xiong Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes of Dietary Fat and Carbohydrate Content Alter Central and Peripheral Clock in Humans

(2015) Olga Pivovarova et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The relaxin family peptide receptors and their ligands: New developments and paradigms in the evolution from jawless fish to mammals

(2014) Sergey Yegorov et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Insulin-regulated Glut4 Translocation

(2014) Paul Duffield Brewer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orphan G Protein–Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size

(2013) James P. Bridges et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

(2013) K. Y. Lee et al.   DIABETES

Lung Surfactant Levels are Regulated by Ig-Hepta/GPR116 by Monitoring Surfactant Protein D

(2013) Taku Fukuzawa et al.   PLoS One

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

(2013) Timo D. Müller et al.   Nature Communications

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

(2013) Mi Young Yang et al.   Cell Reports

Protocol for effective differentiation of 3T3-L1 cells to adipocytes

(2012) Katja Zebisch et al.   ANALYTICAL BIOCHEMISTRY

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Adipose tissue deletion ofGpr116impairs insulin sensitivity through modulation of adipose function

(2012) Tao Nie et al.   FEBS LETTERS

The regulation of integrin function by divalent cations

(2012) Kun Zhang et al.   Cell Adhesion & Migration

The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

(2012) Simone Prömel et al.   Cell Reports

Insulin-sensitive obesity

(2010) Nora Klöting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cross-Talk Between PKA and Akt Protects Endothelial Cells From Apoptosis in the Late Ischemic Preconditioning

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Defining and Characterizing the Progression of Type 2 Diabetes

(2009) V. A. Fonseca   DIABETES CARE