Liver governs adipose remodelling via extracellular vesicles in response to lipid overload

Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart

(2018) Zhong Chen et al.   CARDIOVASCULAR RESEARCH

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

(2018) Clair Crewe et al.   CELL

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance

(2017) Ruth C. R. Meex et al.   Nature Reviews Endocrinology

Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges

(2017) Nicholas L. Syn et al.   TRENDS IN BIOTECHNOLOGY

GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary

(2017) Chen Jiang et al.   PLoS Genetics

Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance

(2016) Pingping Li et al.   CELL

Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis

(2016) Wonhyo Seo et al.   HEPATOLOGY

Metabolic interplay between white, beige, brown adipocytes and the liver

(2016) Ludger Scheja et al.   JOURNAL OF HEPATOLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosome-Mediated Metastasis: From Epithelial–Mesenchymal Transition to Escape from Immunosurveillance

(2016) Nicholas Syn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

(2016) Carolina Villarroya-Beltri et al.   Nature Communications

Hepatitis C Virus Infection Induces Autocrine Interferon Signaling by Human Liver Endothelial Cells and Release of Exosomes, Which Inhibits Viral Replication

(2015) Silvia Giugliano et al.   GASTROENTEROLOGY

Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway

(2015) Weiwei Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation

(2015) Shan Jiang et al.   JOURNAL OF PATHOLOGY

The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure

(2015) Na Xu et al.   JOURNAL OF PATHOLOGY

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

(2015) Miranda Y. Fong et al.   NATURE CELL BIOLOGY

Hepatokines as a Link between Obesity and Cardiovascular Diseases

(2015) Hye Jin Yoo et al.   Diabetes & Metabolism Journal

miRNA let-7e targeting MMP9 is involved in adipose-derived stem cell differentiation toward epithelia

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Molecular Mechanisms of RNA Interference

(2013) Ross C. Wilson et al.   Annual Review of Biophysics

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

(2013) N. Turner et al.   DIABETOLOGIA

Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes

(2013) Andreas L. Birkenfeld et al.   HEPATOLOGY

Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells

(2013) Li Chen et al.   HEPATOLOGY

Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection

(2013) Xiu-Xing Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of hepatokines in metabolism

(2013) Norbert Stefan et al.   Nature Reviews Endocrinology

Interactions among bone, liver, and adipose tissue predisposing to diabesity and fatty liver

(2013) Giovanni Musso et al.   TRENDS IN MOLECULAR MEDICINE

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

(2012) Haruya Ohno et al.   Cell Metabolism

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry

(2012) Els J van der Vlist et al.   Nature Protocols

Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

(2011) Takayuki Kogure et al.   HEPATOLOGY

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/β-catenin signaling pathway

(2010) Limei Qin et al.   BMC GENOMICS

Regional differences in cellular mechanisms of adipose tissue gain with overfeeding

(2010) Y. D. Tchoukalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Down-regulation of CD105 is associated with multi-lineage differentiation in human umbilical cord blood-derived mesenchymal stem cells

(2009) Hye Jin Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance

(2009) Z.-b. Deng et al.   DIABETES

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism

(2008) K. Ganesh Kumar et al.   Cell Metabolism