Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet–induced obesity

Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee

(2019) Jonathon Charlesworth et al.   BMC MUSCULOSKELETAL DISORDERS

Obesity, Metabolic Syndrome, and Musculoskeletal Disease: Common Inflammatory Pathways Suggest a Central Role for Loss of Muscle Integrity

(2018) Kelsey H. Collins et al.   Frontiers in Physiology

Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues

(2017) Rajan Singh et al.   ENDOCRINOLOGY

Follistatin Gene Therapy for Sporadic Inclusion Body Myositis Improves Functional Outcomes

(2017) Jerry R. Mendell et al.   MOLECULAR THERAPY

Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2

(2017) Christoph Wallner et al.   Scientific Reports

Review: Metabolic Regulation of Inflammation in Osteoarthritis

(2016) Francis Berenbaum et al.   Arthritis & Rheumatology

Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus

(2016) Daisuke Hamada et al.   Arthritis & Rheumatology

Osteoarthritis and the risk of cardiovascular disease: a meta-analysis of observational studies

(2016) Haoran Wang et al.   Scientific Reports

A High-Fat High-Sucrose Diet Rapidly Alters Muscle Integrity, Inflammation and Gut Microbiota in Male Rats

(2016) Kelsey H. Collins et al.   Scientific Reports

The association between chronic pain and obesity

(2015) Akiko Okifuji et al.   Journal of Pain Research

Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status

(2015) Theresa Schöttl et al.   Molecular Metabolism

Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury

(2014) Chia-Lung Wu et al.   ANNALS OF THE RHEUMATIC DISEASES

Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations

(2014) Holly A. Leddy et al.   FASEB JOURNAL

All-Cause Mortality and Serious Cardiovascular Events in People with Hip and Knee Osteoarthritis: A Population Based Cohort Study

(2014) Gillian A. Hawker et al.   PLoS One

Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials

(2014) S. U. Dombrowski et al.   BMJ-British Medical Journal

A commentary on modelling osteoarthritis pain in small animals

(2013) A.M. Malfait et al.   OSTEOARTHRITIS AND CARTILAGE

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

(2012) Jorge L. Ruas et al.   CELL

The influence of follistatin on mechanical properties of bone tissue in growing mice with overexpression of follistatin

(2012) Anna Gajos-Michniewicz et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism

(2012) Melissa F Jackson et al.   JOURNAL OF ENDOCRINOLOGY

Regeneration versus fibrosis in skeletal muscle

(2011) Adam L. Moyer et al.   CURRENT OPINION IN RHEUMATOLOGY

Bone morphogenetic protein-2 and spinal arthrodesis: the basic science perspective on protein interaction with the nervous system

(2011) Anton E. Dmitriev et al.   Spine Journal

High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury

(2011) Robert A Mooney et al.   ARTHRITIS RESEARCH & THERAPY

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

(2009) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

(2008) Yasuhiro Izumiya et al.   Cell Metabolism

Increased Secretion and Expression of Myostatin in Skeletal Muscle From Extremely Obese Women

(2008) D. S. Hittel et al.   DIABETES

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

(2007) Masashi Nakatani et al.   FASEB JOURNAL