Progress in Research on TLR4-Mediated Inflammatory Response Mechanisms in Brain Injury after Subarachnoid Hemorrhage

Bumetanide lowers acute hydrocephalus in a rat model of subarachnoid hemorrhage

(2022) Thomas Metayer et al.   ACTA NEUROCHIRURGICA

Melatonin affects hypoxia-inducible factor 1α and ameliorates delayed brain injury following subarachnoid hemorrhage via H19/miR-675/HIF1A/TLR4

(2022) Zhijian Xu et al.   Bioengineered

HMGB1-Mediated Activation of the Inflammatory-Reparative Response Following Myocardial Infarction

(2022) Eleonora Foglio et al.   Cells

RIP1 post-translational modifications

(2022) Eugene Varfolomeev et al.   BIOCHEMICAL JOURNAL

The mechanism of HMGB1 secretion and release

(2022) Ruochan Chen et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage

(2022) Xiaowei Fei et al.   Journal of Neuroinflammation

Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke

(2022) Jun Wang et al.   Journal of Neuroinflammation

RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway

(2022) Jie Fang et al.   Frontiers in Pharmacology

Gestational Leucylation Suppresses Embryonic T‐Box Transcription Factor 5 Signal and Causes Congenital Heart Disease

(2022) Xuan Zhang et al.   Advanced Science

Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway

(2022) Neil D. Perkins   BIOCHEMICAL JOURNAL

Heme oxygenase-1 may mediate early inflammatory response of intracerebral hemorrhage through Toll-like receptor 4 signaling pathway.

(2022) Yuejia Song et al.   CURRENT NEUROVASCULAR RESEARCH

Therapeutic Effect of Mitochondrial Division Inhibitor-1 (Mdivi-1) on Hyperglycemia-Exacerbated Early and Delayed Brain Injuries after Experimental Subarachnoid Hemorrhage

(2022) Chia-Li Chung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The RHIM of the Immune Adaptor Protein TRIF Forms Hybrid Amyloids with Other Necroptosis-Associated Proteins

(2022) Max O. D. G. Baker et al.   MOLECULES

Microglial TLR4 is Critical for Neuronal Injury and Cognitive Dysfunction in Subarachnoid Hemorrhage

(2022) Rezwanul Islam et al.   Neurocritical Care

Shared decision-making in the management of patients with inflammatory bowel disease

(2022) Kai Song et al.   WORLD JOURNAL OF GASTROENTEROLOGY

miR‑30e‑5p attenuates neuronal deficit and inflammation of rats with intracerebral hemorrhage by regulating TLR4

(2022) Haipeng Song et al.   Experimental and Therapeutic Medicine

Gut microbiota on admission as predictive biomarker for acute necrotizing pancreatitis

(2022) Menglian Zou et al.   Frontiers in Immunology

Sleep deprivation aggravates brain injury after experimental subarachnoid hemorrhage via TLR4-MyD88 pathway

(2021) Ye-Ping Xu et al.   Aging-US

Role of TREM-1 in the development of early brain injury after subarachnoid hemorrhage

(2021) Xin-Gang Sun et al.   EXPERIMENTAL NEUROLOGY

Role of Adaptor Protein Myeloid Differentiation 88 (MyD88) in Post-Subarachnoid Hemorrhage Inflammation: A Systematic Review

(2021) Hammad Ahmed et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Toll-Like Receptors Gene Polymorphisms in Autoimmune Disease

(2021) Yingchi Zhang et al.   Frontiers in Immunology

TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1

(2021) Jian Zhao et al.   CELL DEATH AND DIFFERENTIATION

Aneurysmal Subarachnoid Hemorrhage: Review of the Pathophysiology and Management Strategies

(2021) Marcey L. Osgood   Current Neurology and Neuroscience Reports

Neuroprotective Strategies in Aneurysmal Subarachnoid Hemorrhage (aSAH)

(2021) Judith Weiland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ponesimod protects against neuronal death by suppressing the activation of A1 astrocytes in early brain injury after experimental subarachnoid hemorrhage

(2021) Lifang Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Differential polarization and activation dynamics of systemic T helper cell subsets after aneurysmal subarachnoid hemorrhage (SAH) and during post-SAH complications

(2021) Shafqat Rasul Chaudhry et al.   Scientific Reports

TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage

(2021) Yangchun Hu et al.   Frontiers in Cell and Developmental Biology

Full‐Atom Model of the Agonist LPS‐Bound Toll‐like Receptor 4 Dimer in a Membrane Environment

(2021) Alejandra Matamoros‐Recio et al.   CHEMISTRY-A EUROPEAN JOURNAL

Analgecine regulates microglia polarization in ischemic stroke by inhibiting NF-κB through the TLR4 MyD88 pathway

(2021) Cuicui Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pharmacological inhibition of TLR4-NF-κB signaling by TAK-242 attenuates hydrocephalus after intraventricular hemorrhage

(2021) Tao Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammation and Oxidative Stress: Potential Targets for Improving Prognosis After Subarachnoid Hemorrhage

(2021) Fan Wu et al.   Frontiers in Cellular Neuroscience

An Update on Antioxidative Stress Therapy Research for Early Brain Injury After Subarachnoid Hemorrhage

(2021) Fa Lin et al.   Frontiers in Aging Neuroscience

Toll-like receptor-4 pathway as a possible molecular mechanism for brain injuries after subarachnoid hemorrhage

(2020) Qunhui Wang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Functional Variation of IL-1R–Associated Kinases in the Conserved MyD88–TRAF6 Pathway during Evolution

(2020) Xinyu Yan et al.   JOURNAL OF IMMUNOLOGY

Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a

(2020) Jinwei Zhang et al.   Nature Communications

Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets

(2020) Christine Tschoe et al.   Journal of Stroke

Aquaporin 1 and the Na+/K+/2Cl− cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system

(2020) Qianliang Li et al.   Fluids and Barriers of the CNS

Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury

(2020) Jason K. Karimy et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

(2020) Jason K. Karimy et al.   Nature Reviews Neurology

Targeting Inflammation Driven by HMGB1

(2020) Huan Yang et al.   Frontiers in Immunology

Roles of Prokineticin 2 in Subarachnoid Hemorrhage-Induced Early Brain Injury via Regulation of Phenotype Polarization in Astrocytes

(2020) Mian Ma et al.   MOLECULAR NEUROBIOLOGY

Hydrogen Sulfide Reduces Cognitive Impairment in Rats After Subarachnoid Hemorrhage by Ameliorating Neuroinflammation Mediated by the TLR4/NF-κB Pathway in Microglia

(2020) Hongzhou Duan et al.   Frontiers in Cellular Neuroscience

TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

(2020) Anna Ciesielska et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RNF216 mediates neuronal injury following experimental subarachnoid hemorrhage through the Arc/Arg3.1‐AMPAR pathway

(2020) Tao Chen et al.   FASEB JOURNAL

HMGB1 in inflammation and cancer

(2020) Shumin Wang et al.   Journal of Hematology & Oncology

CrossTalk opposing view: NKCC1 in the luminal membrane of choroid plexus is outwardly directed under basal conditions and contributes directly to cerebrospinal fluid secretion

(2020) N. MacAulay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aneurysmal Subarachnoid Hemorrhage: the Last Decade

(2020) Sean N. Neifert et al.   Translational Stroke Research

Recombinant Ricin Toxin Binding Subunit B (RTB) Stimulates Production of TNF-α by Mouse Macrophages Through Activation of TLR4 Signaling Pathway

(2020) Na Xu et al.   Frontiers in Pharmacology

TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-γ Production during Bacterial Infection

(2020) Dong Oh Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oleanolic acid exerts neuroprotective effects in subarachnoid hemorrhage rats through SIRT1-mediated HMGB1 deacetylation

(2020) Yuwei Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The role of immune inflammation in aneurysmal subarachnoid hemorrhage

(2020) Zeyu Zhang et al.   EXPERIMENTAL NEUROLOGY

Prestimulation of Microglia Through TLR4 Pathway Promotes Interferon Beta Expression in a Rat Model of Alzheimer’s Disease

(2019) Niloufar Yousefi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MiR-124 Enriched Exosomes Promoted the M2 Polarization of Microglia and Enhanced Hippocampus Neurogenesis After Traumatic Brain Injury by Inhibiting TLR4 Pathway

(2019) Yongxiang Yang et al.   NEUROCHEMICAL RESEARCH

Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population

(2019) Nima Etminan et al.   JAMA Neurology

LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats

(2019) Jianhua Peng et al.   Redox Biology

A review on the management of cerebral vasospasm following aneurysmal subarachnoid haemorrhage

(2019) Kenny Li et al.   World Neurosurgery

Stearoyl lysophosphatidylcholine inhibits LPS-induced extracellular release of HMGB1 through the G2A/calcium/CaMKKβ/AMPK pathway

(2019) Hui Quan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Early Brain Injury After Poor-Grade Subarachnoid Hemorrhage

(2019) Verena Rass et al.   Current Neurology and Neuroscience Reports

The role of TLR4 and HO‐1 in neuroinflammation after subarachnoid hemorrhage

(2019) Yosuke Akamatsu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Dexmedetomidine inhibits the lipopolysaccharide‐stimulated inflammatory response in microglia through the pathway involving TLR4 and NF‐κB

(2019) Xue‐Yue Zhou et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Toll-like receptor bioactivity in endothelial progenitor cells

(2019) Morteza Heidarzadeh et al.   CELL AND TISSUE RESEARCH

Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling

(2019) Ka-Young Ryu et al.   Journal of Neuroinflammation

Inflammation in delayed ischemia and functional outcomes after subarachnoid hemorrhage

(2019) Sung-Ho Ahn et al.   Journal of Neuroinflammation

β-Caryophyllene protects against ischemic stroke by promoting polarization of microglia toward M2 phenotype via the TLR4 pathway

(2019) Xiaocui Tian et al.   LIFE SCIENCES

Curcumin Mitigates Neuro-Inflammation by Modulating Microglia Polarization Through Inhibiting TLR4 Axis Signaling Pathway Following Experimental Subarachnoid Hemorrhage

(2019) YongYue Gao et al.   Frontiers in Neuroscience

Is Alzheimer’s disease an inflammasomopathy?

(2019) Claudia F. Pereira et al.   AGEING RESEARCH REVIEWS

Treatment targets for M2 microglia polarization in ischemic stroke

(2018) Ji wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism

(2018) Dongpei Yin et al.   BRAIN RESEARCH

Sodium butyrate alleviates LPS-induced acute lung injury in mice via inhibiting HMGB1 release

(2018) Na Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Role of Damage Associated Molecular Pattern Molecules (DAMPs) in Aneurysmal Subarachnoid Hemorrhage (aSAH)

(2018) Shafqat Chaudhry et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TANK-binding kinase 1 and Janus kinase 2 play important roles in the regulation of mitogen-activated protein kinase phosphatase-1 expression after toll-like receptor 4 activation

(2018) Eunji Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glycyrrhizin suppresses the expressions of HMGB1 and ameliorates inflammative effect after acute subarachnoid hemorrhage in rat model

(2018) Chengcheng Ieong et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Peroxiredoxin 2 activates microglia by interacting with Toll-like receptor 4 after subarachnoid hemorrhage

(2018) Yue Lu et al.   Journal of Neuroinflammation

Lycopene mitigates β-amyloid induced inflammatory response and inhibits NF-κB signaling at the choroid plexus in early stages of Alzheimer’s disease rats

(2018) Chong-Bin Liu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity

(2018) Sujun Li et al.   MOLECULAR MEDICINE

Identifying the inhibition of TIR proteins involved in TLR signalling as an anti-inflammatory strategy

(2018) U. Saqib et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Neuroinflammation as a Target for Intervention in Subarachnoid Hemorrhage

(2018) Airton Leonardo de Oliveira Manoel et al.   Frontiers in Neurology

HSP110 and MYD88: blame the chaperone

(2018) R. Eric Davis   BLOOD

Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll-like receptor 4 signaling pathway

(2018) Xiangsheng Zhang et al.   FASEB JOURNAL

Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice

(2018) Jinwei Pang et al.   Translational Stroke Research

The Role of Toll-Like Receptor in Inflammation and Tumor Immunity

(2018) Xiaohong Cen et al.   Frontiers in Pharmacology

Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway

(2018) Fu-yi Liu et al.   Journal of Neuroinflammation

Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity

(2018) Colm Cunningham et al.   NEUROSCIENTIST

Modified Citrus Pectin Prevents Blood-Brain Barrier Disruption in Mouse Subarachnoid Hemorrhage by Inhibiting Galectin-3

(2018) Hirofumi Nishikawa et al.   STROKE

IFN-γ Producing Th1 Cells Induce Different Transcriptional Profiles in Microglia and Astrocytes

(2018) Chittappen K. Prajeeth et al.   Frontiers in Cellular Neuroscience

Toll-like receptors in mycobacterial infection

(2017) Ann Vu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Post-hemorrhagic hydrocephalus: Recent advances and new therapeutic insights

(2017) Qianwei Chen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Spontaneous subarachnoid haemorrhage

(2017) R Loch Macdonald et al.   LANCET

Vitexin alleviates lipopolysaccharide-induced islet cell injury by inhibiting HMGB1 release

(2017) Feifei Wang et al.   Molecular Medicine Reports

Long-Lasting Cerebral Vasospasm, Microthrombosis, Apoptosis and Paravascular Alterations Associated with Neurological Deficits in a Mouse Model of Subarachnoid Hemorrhage

(2017) Mohamad El Amki et al.   MOLECULAR NEUROBIOLOGY

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

(2017) Jason K Karimy et al.   NATURE MEDICINE

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

(2017) Thomas Ve et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Toll-like receptor 4 as a possible therapeutic target for delayed brain injuries after aneurysmal subarachnoid hemorrhage

(2017) Hidenori Suzuki et al.   Neural Regeneration Research

Glycyrrhizic acid exerts anti-inflammatory effect to improve cerebral vasospasm secondary to subarachnoid hemorrhage in a rat model

(2017) Yi Li et al.   NEUROLOGICAL RESEARCH

Effect of curcumin on acute spinal cord injury in mice via inhibition of inflammation and TAK1 pathway

(2017) Nanwen Zhang et al.   Pharmacological Reports

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

(2017) Thomas Ve et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88

(2017) Jiro Sakai et al.   Scientific Reports

TLR and TNF-R1 activation of the MKK3/MKK6-p38  axis in macrophages is mediated by TPL-2 kinase

(2016) M. J. Pattison et al.   BIOCHEMICAL JOURNAL

MicroRNA-27a Negatively Modulates the Inflammatory Response in Lipopolysaccharide-Stimulated Microglia by Targeting TLR4 and IRAK4

(2016) Yan-ni Lv et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Hyperbaric Oxygen Intervention Modulates Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats: Possible Involvement of TLR4/NF-κ B-Mediated Signaling Pathway

(2016) Hao Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways

(2016) Anjali Roy et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

cFLIPLInterrupts IRF3–CBP–DNA Interactions To Inhibit IRF3-Driven Transcription

(2016) Lauren T. Gates et al.   JOURNAL OF IMMUNOLOGY

The HMGB1 C-Terminal Tail Regulates DNA Bending

(2016) Rebecca H. Blair et al.   JOURNAL OF MOLECULAR BIOLOGY

LPS Pretreatment Provides Neuroprotective Roles in Rats with Subarachnoid Hemorrhage by Downregulating MMP9 and Caspase3 Associated with TLR4 Signaling Activation

(2016) Ting-Hua Wang et al.   MOLECULAR NEUROBIOLOGY

Effects of Toll-Like Receptor 4 Antagonists Against Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Mice

(2016) Fumihiro Kawakita et al.   MOLECULAR NEUROBIOLOGY

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Pentoxifylline Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats: Possibly via Inhibiting TLR 4/NF-κB Signaling Pathway

(2016) Da-yong Xia et al.   NEUROCHEMICAL RESEARCH

HMGB1 as biomarker and drug target

(2016) Emilie Venereau et al.   PHARMACOLOGICAL RESEARCH

Anti-high mobility group box-1 (HMGB1) antibody attenuates delayed cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats

(2016) Jun Haruma et al.   Scientific Reports

High-mobility group box 1 promotes extracellular matrix synthesis and wound repair in human bronchial epithelial cells

(2015) Oluwaseun O. Ojo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Baincalein alleviates early brain injury after experimental subarachnoid hemorrhage in rats: Possible involvement of TLR4/NF-κB-mediated inflammatory pathway

(2015) Chun-xi Wang et al.   BRAIN RESEARCH

Fisetin alleviates early brain injury following experimental subarachnoid hemorrhage in rats possibly by suppressing TLR 4/NF-κB signaling pathway

(2015) Chen-hui Zhou et al.   BRAIN RESEARCH

Apigenin protects blood–brain barrier and ameliorates early brain injury by inhibiting TLR4-mediated inflammatory pathway in subarachnoid hemorrhage rats

(2015) Tingting Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Methemoglobin Is an Endogenous Toll-Like Receptor 4 Ligand—Relevance to Subarachnoid Hemorrhage

(2015) Min Kwon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Toll-like receptor 4 (TLR4) is correlated with delayed cerebral ischemia (DCI) and poor prognosis in aneurysmal subarachnoid hemorrhage

(2015) Chunxiao Ma et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Toll-like receptor signalling through macromolecular protein complexes

(2015) Clare E. Bryant et al.   MOLECULAR IMMUNOLOGY

Toll-like Receptor 4 (TLR4) is Associated with Cerebral Vasospasm and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage

(2015) Chunxiao MA et al.   NEUROLOGIA MEDICO-CHIRURGICA

HMGB1 may act via RAGE to promote angiogenesis in the later phase after intracerebral hemorrhage

(2015) C. Lei et al.   NEUROSCIENCE

Effector molecules released by Th1 but not Th17 cells drive an M1 response in microglia

(2014) Chittappen K. Prajeeth et al.   BRAIN BEHAVIOR AND IMMUNITY

Ursolic acid alleviates early brain injury after experimental subarachnoid hemorrhage by suppressing TLR4-mediated inflammatory pathway

(2014) Tingting Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Early release of high-mobility group box 1 (HMGB1) from neurons in experimental subarachnoid hemorrhage in vivo and in vitro

(2014) Qing Sun et al.   Journal of Neuroinflammation

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

(2014) B. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins

(2013) M. Obayed Ullah et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Death domain complex of the TNFR-1, TRADD, and RIP1 proteins for death-inducing signaling

(2013) Young-Hoon Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experimental subarachnoid hemorrhage: possible involvement of TLR4-mediated inflammatory pathway

(2013) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Glycyrrhizic acid confers neuroprotection after subarachnoid hemorrhage via inhibition of high mobility group box-1 protein: A hypothesis for novel therapy of subarachnoid hemorrhage

(2013) Qing Sun et al.   MEDICAL HYPOTHESES

Unknown

(2013) Sodam Kim et al.   MOLECULAR MEDICINE

TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation

(2013) Hui Qiu et al.   VIROLOGICA SINICA

The Blood–Brain Barrier Permeability of 18β-Glycyrrhetinic Acid, a Major Metabolite of Glycyrrhizin in Glycyrrhiza Root, a Constituent of the Traditional Japanese Medicine Yokukansan

(2012) Masahiro Tabuchi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Increased aquaporin-1 and Na+-K+-2Cl- cotransporter 1 expression in choroid plexus leads to blood-cerebrospinal fluid barrier disruption and necrosis of hippocampal CA1 cells in acute rat models of hyponatremia

(2012) Jaehyun Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of high-mobility group box1 on cerebral angiogenesis and neurogenesis after intracerebral hemorrhage

(2012) C. Lei et al.   NEUROSCIENCE

Cell death starts early after subarachnoid hemorrhage

(2012) Victor Friedrich et al.   NEUROSCIENCE LETTERS

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

(2009) S. Fernandez-Lizarbe et al.   JOURNAL OF IMMUNOLOGY

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

(2009) Ping-Hui Tseng et al.   NATURE IMMUNOLOGY

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)

(2008) Judy R. van Beijnum et al.   ANGIOGENESIS