Microglial TLR4 is Critical for Neuronal Injury and Cognitive Dysfunction in Subarachnoid Hemorrhage

Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)

(2021) Rebecca Heinz et al.   Journal of Neuroinflammation

TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage

(2021) Yangchun Hu et al.   Frontiers in Cell and Developmental Biology

Defining the Mechanism of Subarachnoid Hemorrhage–Induced Pyrexia

(2020) Ajith J. Thomas et al.   Neurotherapeutics

Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population

(2019) Nima Etminan et al.   JAMA Neurology

Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury

(2019) Andreas Hedblom et al.   Cell Death & Disease

The role of TLR4 and HO‐1 in neuroinflammation after subarachnoid hemorrhage

(2019) Yosuke Akamatsu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

(2018) Dunja Mrdjen et al.   IMMUNITY

Myeloid cells expressing high level of CD45 are associated with a distinct activated phenotype in glioma

(2017) Susan Brandenburg et al.   IMMUNOLOGIC RESEARCH

Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies

(2017) Harald Lund et al.   Frontiers in Aging Neuroscience

Heme oxygenase-1-mediated neuroprotection in subarachnoid hemorrhage via intracerebroventricular deferoxamine

(2016) Robert H. LeBlanc et al.   Journal of Neuroinflammation

Microglia inflict delayed brain injury after subarachnoid hemorrhage

(2015) Ulf C. Schneider et al.   ACTA NEUROPATHOLOGICA

Methemoglobin Is an Endogenous Toll-Like Receptor 4 Ligand—Relevance to Subarachnoid Hemorrhage

(2015) Min Kwon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1

(2015) Nils Schallner et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

LPS or ethanol triggers clathrin- and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes

(2013) Maya Pascual-Lucas et al.   JOURNAL OF NEUROCHEMISTRY

The role of microglia and the TLR4 pathway in neuronal apoptosis and vasospasm after subarachnoid hemorrhage

(2013) Khalid A Hanafy   Journal of Neuroinflammation

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Heparin Reduces Neuroinflammation and Transsynaptic Neuronal Apoptosis in a Model of Subarachnoid Hemorrhage

(2012) J. Marc Simard et al.   Translational Stroke Research

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke

(2011) J. V. Faustino et al.   JOURNAL OF NEUROSCIENCE

Cerebral Infarction After Subarachnoid Hemorrhage Contributes to Poor Outcome by Vasospasm-Dependent and -Independent Effects

(2011) Mervyn D.I. Vergouwen et al.   STROKE

Relationship between brain interstitial fluid tumor necrosis factor-α and cerebral vasospasm after aneurysmal subarachnoid hemorrhage

(2010) Khalid A. Hanafy et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Subarachnoid Hemorrhage Induces Gliosis and Increased Expression of the Pro-inflammatory Cytokine High Mobility Group Box 1 Protein

(2010) Kentaro Murakami et al.   Translational Stroke Research

Selective targeting of perivascular macrophages for clearance of  -amyloid in cerebral amyloid angiopathy

(2009) C. A. Hawkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnosing Delayed Cerebral Ischemia With Different CT Modalities in Patients With Subarachnoid Hemorrhage With Clinical Deterioration

(2009) Jan Willem Dankbaar et al.   STROKE

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

(2009) Joshua B. Bederson et al.   STROKE

Macrophage depletion diminishes implant-wear-induced inflammatory osteolysis in a mouse model

(2007) Weiping Ren et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A