The Role of Toll-Like Receptor in Inflammation and Tumor Immunity

Flagellin increases death receptor-mediated cell death in a RIP1-dependent manner

(2018) Dora Hancz et al.   IMMUNOLOGY LETTERS

Promoting the accumulation of tumor-specific T cells in tumor tissues by dendritic cell vaccines and chemokine-modulating agents

(2018) Nataša Obermajer et al.   Nature Protocols

The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis

(2017) Lingling Ou et al.   International Journal of Nanomedicine

Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells

(2017) Shu-Hao Chang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

High-mobility group box 1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells

(2017) Xi-Long Zhao et al.   JOURNAL OF PATHOLOGY

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells

(2017) E J Cheadle et al.   LEUKEMIA

BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells

(2017) Alexis Combes et al.   Nature Communications

The Toll–Like Receptor 2/6 Agonist, FSL–1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome

(2017) Cathryn J. Kurkjian et al.   Scientific Reports

Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils

(2016) Yanfang Liu et al.   CANCER CELL

Poly(I:C) potentiates Bacillus Calmette–Guérin immunotherapy for bladder cancer

(2016) Cherifa Ayari et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma

(2016) Daoxiang Zhang et al.   CLINICAL CANCER RESEARCH

Nano-biointeractions of PEGylated and bare reduced graphene oxide on lung alveolar epithelial cells: A comparative in vitro study

(2016) S.C. Reshma et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Imiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell line

(2016) Shi-Wei Huang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies

(2016) Stavroula Ntoufa et al.   SEMINARS IN CANCER BIOLOGY

Toll-like receptor 3 ligand specifically induced bronchial epithelial cell death in caspase dependent manner and functionally upregulated Fas expression

(2016) Yuta Koizumi et al.   ALLERGOLOGY INTERNATIONAL

Medical Countermeasures for Radiation Exposure and Related Injuries

(2015) Vijay K. Singh et al.   HEALTH PHYSICS

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors

(2015) Sebastian Schölch et al.   Oncotarget

Human Tumor Antigens and Cancer Immunotherapy

(2015) Nathalie Vigneron   Biomed Research International

Resiquimod as an Immunologic Adjuvant for NY-ESO-1 Protein Vaccination in Patients with High-Risk Melanoma

(2015) R. L. Sabado et al.   Cancer Immunology Research

Tumor cell death by pattern-sensing of exogenous RNA: Tumor cell TLR3 directly induces necroptosis by poly(I:C) in vivo, independent of immune effector-mediated tumor shrinkage

(2015) Hiromi Takaki et al.   OncoImmunology

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination

(2014) Zhenzhen Zhan et al.   Autophagy

Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine

(2014) Li-Zhen He et al.   Cellular & Molecular Immunology

Immunization of Malignant Melanoma Patients with Full-Length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod as Vaccine Adjuvant

(2014) S. Adams et al.   JOURNAL OF IMMUNOLOGY

AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells

(2013) CHINGJU LIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift

(2013) Silvia C. Formenti et al.   JNCI-Journal of the National Cancer Institute

The Yin and Yang of Toll-like receptors in cancer

(2013) J-P Pradere et al.   ONCOGENE

The TLR7 agonist imiquimod as an adjuvant for radiotherapy-elicited in situ vaccination against breast cancer

(2013) Sandra Demaria et al.   OncoImmunology

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

(2012) L. Ouyang et al.   CELL PROLIFERATION

New developments in Toll-like receptor targeted therapeutics

(2012) Dympna J Connolly et al.   CURRENT OPINION IN PHARMACOLOGY

CBLB613: A TLR 2/6 Agonist, Natural Lipopeptide ofMycoplasma arginini, as a Novel Radiation Countermeasure

(2012) Vijay K. Singh et al.   RADIATION RESEARCH

Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis

(2012) Sana Intidhar Labidi-Galy et al.   OncoImmunology

Trial Watch

(2012) Lorenzo Galluzzi et al.   OncoImmunology

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

TLR1/TLR2 Agonist Induces Tumor Regression by Reciprocal Modulation of Effector and Regulatory T Cells

(2011) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Overexpression of TLR3, TLR4, TLR7 and TLR9 in esophageal squamous cell carcinoma

(2011) Ilyar Sheyhidin   WORLD JOURNAL OF GASTROENTEROLOGY

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis

(2010) Salomé González-Reyes et al.   BMC CANCER

Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence

(2010) Salomé González-Reyes et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy

(2010) C. S. Shi et al.   Science Signaling

Toll-like receptor expression in normal ovary and ovarian tumors

(2009) Mingfu Zhou et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Programmed Cell Death Pathways and Current Antitumor Targets

(2009) Mei Lan Tan et al.   PHARMACEUTICAL RESEARCH

Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer

(2009) L. A. J. O'Neill et al.   PHARMACOLOGICAL REVIEWS