Role of Adaptor Protein Myeloid Differentiation 88 (MyD88) in Post-Subarachnoid Hemorrhage Inflammation: A Systematic Review

Toll-like receptor-4 pathway as a possible molecular mechanism for brain injuries after subarachnoid hemorrhage

(2020) Qunhui Wang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury

(2020) Jason K. Karimy et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Targeting High Mobility Group Box 1 in Subarachnoid Hemorrhage: A Systematic Review

(2020) Sajjad Muhammad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Downregulation of Inflammatory Cytokine Release from IL-1β and LPS-Stimulated PBMC Orchestrated by ST2825, a MyD88 Dimerisation Inhibitor

(2020) Sergio Ramírez-Pérez et al.   MOLECULES

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care

(2019) Anna Tarocco et al.   Cell Death & Disease

Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4/NF-kB pathway

(2019) Morena Zusso et al.   Journal of Neuroinflammation

DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation

(2019) Joel Zindel et al.   Annual Review of Pathology-Mechanisms of Disease

Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling

(2019) Ka-Young Ryu et al.   Journal of Neuroinflammation

Curcumin Mitigates Neuro-Inflammation by Modulating Microglia Polarization Through Inhibiting TLR4 Axis Signaling Pathway Following Experimental Subarachnoid Hemorrhage

(2019) YongYue Gao et al.   Frontiers in Neuroscience

DAMPs and NETs in Sepsis

(2019) Naomi-Liza Denning et al.   Frontiers in Immunology

Recent Advances in Stem Cell Research in Subarachnoid Hemorrhage

(2019) Zhijun Song et al.   STEM CELLS AND DEVELOPMENT

Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway

(2018) Ling-yun Wu et al.   BEHAVIOURAL NEUROLOGY

Systemic High-Mobility Group Box-1

(2018) Shafqat R. Chaudhry et al.   CRITICAL CARE MEDICINE

Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway

(2018) Xiao Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Role of Damage Associated Molecular Pattern Molecules (DAMPs) in Aneurysmal Subarachnoid Hemorrhage (aSAH)

(2018) Shafqat Chaudhry et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Peroxiredoxin 2 activates microglia by interacting with Toll-like receptor 4 after subarachnoid hemorrhage

(2018) Yue Lu et al.   Journal of Neuroinflammation

TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models

(2018) Gerónimo Fernández et al.   MOLECULAR THERAPY

Heparin: The Silver Bullet of Aneurysmal Subarachnoid Hemorrhage?

(2018) Nicolas K. Khattar et al.   Frontiers in Neurology

Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll-like receptor 4 signaling pathway

(2018) Xiangsheng Zhang et al.   FASEB JOURNAL

Melatonin and inflammation - story of a double-edged blade

(2018) Rüdiger Hardeland   JOURNAL OF PINEAL RESEARCH

Removal of microglial-specific MyD88 signaling alters dentate gyrus doublecortin and enhances opioid addiction-like behaviors

(2018) Phillip D. Rivera et al.   BRAIN BEHAVIOR AND IMMUNITY

Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway

(2018) Fu-yi Liu et al.   Journal of Neuroinflammation

Temporal profile of serum mitochondrial DNA (mtDNA) in patients with aneurysmal subarachnoid hemorrhage (aSAH)

(2018) Shafqat Rasul Chaudhry et al.   MITOCHONDRION

Sterile Inflammation, Potential Target in Aneurysmal Subarachnoid Hemorrhage

(2018) Shafqat Rasul Chaudhry et al.   World Neurosurgery

Heparin and Heparin-Derivatives in Post-Subarachnoid Hemorrhage Brain Injury: A Multimodal Therapy for a Multimodal Disease

(2017) Erik Hayman et al.   MOLECULES

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

(2017) Jason K Karimy et al.   NATURE MEDICINE

Toll-like receptor 4 as a possible therapeutic target for delayed brain injuries after aneurysmal subarachnoid hemorrhage

(2017) Hidenori Suzuki et al.   Neural Regeneration Research

Inhibition of myeloid differentiation primary response protein 88 provides neuroprotection in early brain injury following experimental subarachnoid hemorrhage

(2017) Huiying Yan et al.   Scientific Reports

Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain

(2017) Luca Posa et al.   CURRENT MEDICINAL CHEMISTRY

Effects of Toll-Like Receptor 4 Antagonists Against Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Mice

(2016) Fumihiro Kawakita et al.   MOLECULAR NEUROBIOLOGY

Unruptured intracranial aneurysms: development, rupture and preventive management

(2016) Nima Etminan et al.   Nature Reviews Neurology

Pentoxifylline Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats: Possibly via Inhibiting TLR 4/NF-κB Signaling Pathway

(2016) Da-yong Xia et al.   NEUROCHEMICAL RESEARCH

Tyrosine Kinase Inhibitor as a new Therapy for Ischemic Stroke and other Neurologic Diseases: is there any Hope for a Better Outcome?

(2015) Iwona Gagalo et al.   Current Neuropharmacology

Heparin and LPS-induced COX-2 expression in airway cells: a link between its anti-inflammatory effects and GAG sulfation

(2015) Na Young Yi et al.   EXPERIMENTAL LUNG RESEARCH

Methemoglobin Is an Endogenous Toll-Like Receptor 4 Ligand—Relevance to Subarachnoid Hemorrhage

(2015) Min Kwon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Controversies in epidemiology of intracranial aneurysms and SAH

(2015) Miikka Korja et al.   Nature Reviews Neurology

Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen

(2015) Mark A. Olson et al.   Scientific Reports

Medical Complications After Aneurysmal Subarachnoid Hemorrhage: An Emerging Contributor to Poor Outcome

(2015) Nima Etminan et al.   World Neurosurgery

Understanding the disease: aneurysmal subarachnoid hemorrhage

(2014) R. Loch Macdonald et al.   INTENSIVE CARE MEDICINE

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

Expression and cell distribution of myeloid differentiation primary response protein 88 in the cerebral cortex following experimental subarachnoid hemorrhage in rats: A pilot study

(2013) Qing Sun et al.   BRAIN RESEARCH

Resveratrol Attenuates Early Brain Injury After Subarachnoid Hemorrhage Through Inhibition of NF-κB-Dependent Inflammatory/MMP-9 Pathway

(2013) An-Wen Shao et al.   CNS Neuroscience & Therapeutics

Role of progesterone in TLR4-MyD88-dependent signaling pathway in pre-eclampsia

(2013) Ying Zhu et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

The role of microglia and the TLR4 pathway in neuronal apoptosis and vasospasm after subarachnoid hemorrhage

(2013) Khalid A Hanafy   Journal of Neuroinflammation

Toll-like receptor 4 signaling in intracerebral hemorrhage-induced inflammation and injury

(2013) Huang Fang et al.   Journal of Neuroinflammation

Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experimental subarachnoid hemorrhage: possible involvement of TLR4-mediated inflammatory pathway

(2013) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol

(2012) Peter B. Jakus et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Progesterone Administration Modulates Cortical TLR4/NF-κB Signaling Pathway after Subarachnoid Hemorrhage in Male Rats

(2011) Zhong Wang et al.   MEDIATORS OF INFLAMMATION

Recombinant osteopontin in cerebral vasospasm after subarachnoid hemorrhage

(2010) Hidenori Suzuki et al.   ANNALS OF NEUROLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation

(2008) D Gosselin et al.   MOLECULAR PSYCHIATRY

Subarachnoid Hemorrhage: Is It Time for a New Direction?

(2008) J. Cahill et al.   STROKE