Dexmedetomidine inhibits the lipopolysaccharide‐stimulated inflammatory response in microglia through the pathway involving TLR4 and NF‐κB

Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia

(2018) Ching-Hua Yeh et al.   PLoS One

Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway

(2017) Jing-jing Zhang et al.   PLoS One

Protective role of dexmedetomidine in unmethylated CpG-induced inflammation responses in BV2 microglia cells

(2016) Chen Chen et al.   FOLIA NEUROPATHOLOGICA

Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial

(2016) Xian Su et al.   LANCET

Anti-Inflammatory Effects of Ginsenoside-Rh2 Inhibits LPS-Induced Activation of Microglia and Overproduction of Inflammatory Mediators Via Modulation of TGF-β1/Smad Pathway

(2016) R Vinoth Kumar et al.   NEUROCHEMICAL RESEARCH

TNF-α receptor antagonist attenuates isoflurane-induced cognitive impairment in aged rats

(2016) NENGLI YANG et al.   Experimental and Therapeutic Medicine

Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia

(2014) Jin-Woo Jeong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dexmedetomidine Inhibits Tumor Necrosis Factor-Alpha and Interleukin 6 in Lipopolysaccharide-Stimulated Astrocytes by Suppression of c-Jun N-Terminal Kinases

(2014) Xiaobao Zhang et al.   INFLAMMATION

Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-κB Pathway

(2014) Yan Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Hemodynamic Response to Dexmedetomidine Loading Dose in Children With and Without Pulmonary Hypertension

(2013) Robert H. Friesen et al.   ANESTHESIA AND ANALGESIA

Inflammation in neurodegenerative diseases - an update

(2013) Sandra Amor et al.   IMMUNOLOGY

Effects of dexmedetomidine on early and late cytokines during polymicrobial sepsis in mice

(2013) Li Xu et al.   INFLAMMATION RESEARCH

Nanog attenuates lipopolysaccharide-induced inflammatory responses by blocking nuclear factor-κB transcriptional activity in BV-2 cells

(2013) Zhihui Duan et al.   NEUROREPORT

Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats

(2012) R. M. Barrientos et al.   JOURNAL OF NEUROSCIENCE

Dexmedetomidine attenuates lipopolysaccharide-induced proinflammatory response in primary microglia

(2012) Mian Peng et al.   JOURNAL OF SURGICAL RESEARCH

High-Dose Dexmedetomidine for Sedation in the Intensive Care Unit: An Evaluation of Clinical Efficacy and Safety

(2011) G Morgan Jones et al.   ANNALS OF PHARMACOTHERAPY

Dexmedetomidine

(2011) Sheridan M. Hoy et al.   DRUGS

Features of Microglia and Neuroinflammation Relevant to Environmental Exposure and Neurotoxicity

(2011) Andrew D. Kraft et al.   International Journal of Environmental Research and Public Health