Qingrequzhuo capsule alleviated methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice through regulating gut microbiota, enhancing gut tight junction and inhibiting the activation of TLR4/NF-κB signaling pathway

Morus alba L. water extract changes gut microbiota and fecal metabolome in mice induced by high‐fat and high‐sucrose diet plus low‐dose streptozotocin

(2022) Yan Du et al.   PHYTOTHERAPY RESEARCH

Effect of Coptis chinensis franch and Magnolia officinalis on intestinal flora and intestinal barrier in a TNBS-induced ulcerative colitis rats model

(2022) Qian Xie et al.   PHYTOMEDICINE

The Microbiota and It’s Correlation With Metabolites in the Gut of Mice With Nonalcoholic Fatty Liver Disease

(2022) Congwei Gu et al.   Frontiers in Cellular and Infection Microbiology

Phyllanthus emblica aqueous extract retards hepatic steatosis and fibrosis in NAFLD mice in association with the reshaping of intestinal microecology

(2022) Xiaomin Luo et al.   Frontiers in Pharmacology

Polyphenols and Polysaccharides from Morus alba L. Fruit Attenuate High-Fat Diet-Induced Metabolic Syndrome Modifying the Gut Microbiota and Metabolite Profile

(2022) Meixia Wan et al.   Foods

The Effect of Qiweibaizhu Powder Crude Polysaccharide on Antibiotic-Associated Diarrhea Mice Is Associated With Restoring Intestinal Mucosal Bacteria

(2022) Cuiru Li et al.   Frontiers in Nutrition

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota

(2022) Koji Hosomi et al.   Nature Communications

Smilax glabra Roxb.: A Review of Its Traditional Usages, Phytochemical Constituents, Pharmacological Properties, and Clinical Applications

(2022) Hao Wu et al.   Drug Design Development and Therapy

Total glycosides contribute to the anti-diarrheal effects of Qiwei Baizhu Powder via regulating gut microbiota and bile acids

(2022) Guozhen Xie et al.   Frontiers in Cellular and Infection Microbiology

Effect of Lactobacillus casei on lipid metabolism and intestinal microflora in patients with alcoholic liver injury

(2021) Xuelong Li et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Jian-Gan-Xiao-Zhi Decoction Alleviates Inflammatory Response in Nonalcoholic Fatty Liver Disease Model Rats through Modulating Gut Microbiota

(2021) Jiabao Liao et al.   Evidence-based Complementary and Alternative Medicine

Chinese Herbal Medicine Decreases Incidence of Cirrhosis in Patients with Non-Alcoholic Fatty Liver Disease in Taiwan: A Propensity Score-Matched Cohort Study

(2021) Chia-Yu Huang et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Preparing for the NASH Epidemic: A Call to Action

(2021) Fasiha Kanwal et al.   GASTROENTEROLOGY

Flavonoids from Whole-Grain Oat Alleviated High-Fat Diet-Induced Hyperlipidemia via Regulating Bile Acid Metabolism and Gut Microbiota in Mice

(2021) Ruiqian Duan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Soyasaponin A 2 Alleviates Steatohepatitis Possibly through Regulating Bile Acids and Gut Microbiota in the Methionine and Choline‐Deficient (MCD) Diet‐induced Nonalcoholic Steatohepatitis (NASH) Mice

(2021) Fei Xiong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice

(2021) Ryo Aoki et al.   Microbiome

Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition

(2021) Jian Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Regulatory Effects of Citrus Peel Powder on Liver Metabolites and Gut Flora in Mice with Non-Alcoholic Fatty Liver Disease (NAFLD)

(2021) Meiyi Hu et al.   Foods

Bacterial Diversity in the Intestinal Mucosa of Dysbiosis Diarrhea Mice Treated with Qiweibaizhu Powder

(2020) Cheng-Xing Long et al.   Gastroenterology Research and Practice

Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota–bile acid–farnesoid X receptor axis

(2020) Hongshan Li et al.   BIOMEDICINE & PHARMACOTHERAPY

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(2020) Adam C. Sheka et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Traditional Chinese medicine Lingguizhugan decoction treating non-alcoholic fatty liver disease with spleen-yang deficiency pattern: Study protocol for a multicenter randomized controlled trial

(2020) Jingjuan Xu et al.   Trials

Anemarrhena asphodeloides modulates gut microbiota and restores pancreatic function in diabetic rats

(2020) Dong Yan et al.   BIOMEDICINE & PHARMACOTHERAPY

Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe−/−mice: role of SIRT1

(2020) Yi Qiao Hua et al.   PHYTOMEDICINE

Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments

(2020) Cheng Peng et al.   Frontiers in Pharmacology

Beneficial effects of exercise on gut microbiota functionality and barrier integrity, and gut-liver crosstalk in an in vivo model of early obesity and non-alcoholic fatty liver disease

(2019) Sara Carbajo-Pescador et al.   Disease Models & Mechanisms

A Purified Anthraquinone-Glycoside Preparation From Rhubarb Ameliorates Type 2 Diabetes Mellitus by Modulating the Gut Microbiota and Reducing Inflammation

(2019) Hong-Xin Cui et al.   Frontiers in Microbiology

Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats

(2019) Ze-Hua Zhao et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Chinese yam (Dioscorea opposita Thunb.) alleviates antibiotic-associated diarrhea, modifies intestinal microbiota, and increases the level of short-chain fatty acids in mice

(2019) Nan Zhang et al.   FOOD RESEARCH INTERNATIONAL

Scutellariae radix and coptidis rhizoma ameliorate glycolipid metabolism of type 2 diabetic rats by modulating gut microbiota and its metabolites

(2019) Suwei Xiao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Coptisine from Coptis chinensis exerts diverse beneficial properties: A concise review

(2019) Jiasi Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors

(2019) Nobuo Fuke et al.   Nutrients

The Role of Probiotics in Nonalcoholic Fatty Liver Disease: A New Insight into Therapeutic Strategies

(2019) Marica Meroni et al.   Nutrients

Gut microbiota in non‐alcoholic fatty liver disease and alcohol‐related liver disease: Current concepts and perspectives

(2019) Juan P. Arab et al.   HEPATOLOGY RESEARCH

An Overview on Citrus aurantium L.: Its Functions as Food Ingredient and Therapeutic Agent

(2018) Ipek Suntar et al.   Oxidative Medicine and Cellular Longevity

Oral hydroxysafflor yellow A reduces obesity in mice by modulating the gut microbiota and serum metabolism

(2018) Juan Liu et al.   PHARMACOLOGICAL RESEARCH

Quantification of Lipid Abundance and Evaluation of Lipid Distribution in Caenorhabditis elegans by Nile Red and Oil Red O Staining

(2018) Wilber Escorcia et al.   Jove-Journal of Visualized Experiments

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

Citrus aurantium L. and Its Flavonoids Regulate TNBS-Induced Inflammatory Bowel Disease through Anti-Inflammation and Suppressing Isolated Jejunum Contraction

(2018) Wei He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota dysbiosis in patients with non-alcoholic fatty liver disease

(2017) Feng Shen et al.   Hepatobiliary & Pancreatic Diseases International

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

Asking the Right Questions With Animal Models: Methionine- and Choline-Deficient Model in Predicting Adverse Drug Reactions in Human NASH

(2017) Hui Li et al.   TOXICOLOGICAL SCIENCES

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

(2017) Da Zhou et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy

(2017) Junli Ma et al.   Nutrients

Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota

(2017) Da Zhou et al.   Scientific Reports

Rheum palmatum L. Attenuates High Fat Diet-Induced Hepatosteatosis by Activating AMP-Activated Protein Kinase

(2016) Mingxing Yang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth

(2016) Martina Goffredo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

(2015) Ji-Young Ann et al.   Genes and Nutrition

Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice

(2015) Ji-Young Ann et al.   Genes and Nutrition

Role of gut microbiota: Obesity and NAFLD

(2014) Venkatanarayana Gangarapu et al.   Turkish Journal of Gastroenterology

Carthamus red from Carthamus tinctorius L. exerts antioxidant and hepatoprotective effect against CCl4-induced liver damage in rats via the Nrf2 pathway

(2013) Shuangchan Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Molecular Characterization of the Fecal Microbiota in Patients with Nonalcoholic Steatohepatitis – A Longitudinal Study

(2013) Vincent Wai-Sun Wong et al.   PLoS One

Traditional Chinese medicines benefit to nonalcoholic fatty liver disease: a systematic review and meta-analysis

(2012) Ke-Qing Shi et al.   MOLECULAR BIOLOGY REPORTS

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

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(2012) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice

(2011) Timea Csak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis

(2010) Ashkan Farhadi et al.   LIVER INTERNATIONAL

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets

(2009) Bingkun Zhang et al.   BRITISH JOURNAL OF NUTRITION