Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
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Title
Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
Authors
Keywords
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Journal
SCIENCE
Volume 378, Issue 6621, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2022-11-18
DOI
10.1126/science.abl7207
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Note: Only part of the references are listed.- scGate: marker-based purification of cell types from heterogeneous single-cell RNA-seq datasets
- (2022) Massimo Andreatta et al. BIOINFORMATICS
- Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model
- (2022) Elisa Donnard et al. PLoS Genetics
- FMRP modulates the Wnt signalling pathway in glioblastoma
- (2022) Giorgia Pedini et al. Cell Death & Disease
- Tumor‐associated macrophages in immunotherapy
- (2021) Shijia Yan et al. FEBS Journal
- miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein
- (2021) Peng-Yin Nie et al. Journal of Neuroinflammation
- A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells
- (2021) Sijin Cheng et al. CELL
- The molecular biology of FMRP: new insights into fragile X syndrome
- (2021) Joel D. Richter et al. NATURE REVIEWS NEUROSCIENCE
- Inference and analysis of cell-cell communication using CellChat
- (2021) Suoqin Jin et al. Nature Communications
- CXCL9-expressing tumor-associated macrophages: new players in the fight against cancer
- (2021) Paola Marie Marcovecchio et al. Journal for ImmunoTherapy of Cancer
- Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression
- (2021) Ziming Jiang et al. Cell Communication and Signaling
- Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity
- (2021) Yugang Guo et al. NATURE IMMUNOLOGY
- Interpretation of T cell states from single-cell transcriptomics data using reference atlases
- (2021) Massimo Andreatta et al. Nature Communications
- Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer
- (2021) Dora Hammerl et al. Nature Communications
- FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
- (2021) Caryn R Hale et al. eLife
- Exosome-Mediated Crosstalk Between Tumor and Tumor-Associated Macrophages
- (2021) Qi Chen et al. Frontiers in Molecular Biosciences
- A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis
- (2020) Caitlin M. Rodriguez et al. NATURE NEUROSCIENCE
- Myc instructs and maintains pancreatic adenocarcinoma phenotype
- (2020) Nicole M Sodir et al. Cancer Discovery
- Acquired Resistance to Immune Checkpoint Inhibitors
- (2020) Adam J. Schoenfeld et al. CANCER CELL
- Identification of FMR1-regulated molecular networks in human neurodevelopment
- (2020) Meng Li et al. GENOME RESEARCH
- CXCR3 Ligands in Cancer and Autoimmunity, Chemoattraction of Effector T Cells, and Beyond
- (2020) Nathan Karin Frontiers in Immunology
- Novel FMRP interaction networks linked to cellular stress
- (2020) Mohamed S. Taha et al. FEBS Journal
- Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors
- (2020) Lorenzo Galluzzi et al. Nature Reviews Clinical Oncology
- The RNA binding protein FMR1 controls selective exosomal miRNA cargo loading during inflammation
- (2020) Ann L. Wozniak et al. JOURNAL OF CELL BIOLOGY
- The Fragile X Mental Retardation Protein regulates RIP1K and colorectal cancer resistance to necroptosis
- (2020) Antonio Di Grazia et al. Cellular and Molecular Gastroenterology and Hepatology
- Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
- (2020) Yeon Hee Park et al. Nature Communications
- Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy
- (2019) Melvyn T. Chow et al. IMMUNITY
- Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
- (2019) Ela Elyada et al. Cancer Discovery
- Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
- (2019) Chiara Cianciaruso et al. Cell Reports
- Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer
- (2019) James W. Opzoomer et al. Frontiers in Immunology
- Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study
- (2019) Johan Staaf et al. NATURE MEDICINE
- A reality check of the accelerated approval of immune-checkpoint inhibitors
- (2019) Jennifer Gill et al. Nature Reviews Clinical Oncology
- Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade
- (2019) Imran G. House et al. CLINICAL CANCER RESEARCH
- New developments on the Encyclopedia of DNA Elements (ENCODE) data portal
- (2019) Yunhai Luo et al. NUCLEIC ACIDS RESEARCH
- Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers
- (2019) Gabriele Galliverti et al. Cancer Immunology Research
- Neutrophils suppress tumor‐infiltrating T cells in colon cancer via matrix metalloproteinase‐mediated activation of TGF β
- (2019) Markus Germann et al. EMBO Molecular Medicine
- Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction
- (2019) Marta Prieto et al. MOLECULAR PSYCHIATRY
- An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion
- (2019) Aikaterini Hatzioannou et al. NATURE IMMUNOLOGY
- Mechanisms of resistance to immune checkpoint inhibitors
- (2018) Russell W Jenkins et al. BRITISH JOURNAL OF CANCER
- GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth
- (2018) Leanne Li et al. CANCER CELL
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
- (2018) Francisco Sanchez-Vega et al. CELL
- Integrated genomic and immunophenotypic classification of pancreatic cancer reveals three distinct subtypes with prognostic/predictive significance
- (2018) Martin Wartenberg et al. CLINICAL CANCER RESEARCH
- Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response
- (2018) Eric Ubil et al. JOURNAL OF CLINICAL INVESTIGATION
- The significance of microsatellite instability in colorectal cancer after controlling for clinicopathological factors
- (2018) Sanghee Kang et al. MEDICINE
- HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein
- (2018) Thomas Maurin et al. NUCLEIC ACIDS RESEARCH
- Handling FMRP and its molecular partners: Structural insights into Fragile X Syndrome
- (2018) Ilda D'Annessa et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Crucial biological functions of CCL7 in cancer
- (2018) Yangyang Liu et al. PeerJ
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- Single sample scoring of molecular phenotypes
- (2018) Momeneh Foroutan et al. BMC BIOINFORMATICS
- Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
- (2018) Terry R. Medler et al. CANCER CELL
- Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models
- (2018) Ioanna Keklikoglou et al. NATURE CELL BIOLOGY
- The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells
- (2017) Francesca Zalfa et al. Cell Death & Disease
- The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
- (2016) Toshiro Moroishi et al. CELL
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration
- (2015) Timothy J. Zumwalt et al. Oncotarget
- Local production of the chemokines CCL5 and CXCL10 attracts CD8+ T lymphocytes into esophageal squamous cell carcinoma
- (2015) Jinyan Liu et al. Oncotarget
- VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer
- (2015) Christian Schafroth et al. Oncotarget
- Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures
- (2015) Daria Prilutsky et al. Molecular Autism
- An Ex vivo Model to Study Hormone Action in the Human Breast
- (2015) George Sflomos et al. Jove-Journal of Visualized Experiments
- Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma
- (2014) John C Castle et al. BMC GENOMICS
- SnapShot: FMRP mRNA Targets and Diseases
- (2014) Emanuela Pasciuto et al. CELL
- Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications
- (2014) Guoyan Xu et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation
- (2013) Rossella Lucá et al. EMBO Molecular Medicine
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Fragile X mental retardation protein and synaptic plasticity
- (2013) Michael S Sidorov et al. Molecular Brain
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
- (2011) Jennifer C. Darnell et al. CELL
- Lymphocytic Reaction to Colorectal Cancer Is Associated with Longer Survival, Independent of Lymph Node Count, Microsatellite Instability, and CpG Island Methylator Phenotype
- (2009) S. Ogino et al. CLINICAL CANCER RESEARCH
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- Prolongation of Cardiac and Islet Allograft Survival by a Blocking Hamster Anti-Mouse CXCR3 Monoclonal Antibody
- (2009) Ravindra Uppaluri et al. TRANSPLANTATION
- Trafficking and function of the tetraspanin CD63
- (2008) Maaike S. Pols et al. EXPERIMENTAL CELL RESEARCH
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