Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction
Authors
Keywords
-
Journal
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-10
DOI
10.1038/s41380-019-0629-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation
- (2019) Brian Tsang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Roles of Post-translational Modifications on α-Synuclein in the Pathogenesis of Parkinson’s Diseases
- (2019) Jiaming Zhang et al. Frontiers in Neuroscience
- Small-Molecule Inhibitors Targeting Protein SUMOylation as Novel Anticancer Compounds
- (2018) Yanfang Yang et al. MOLECULAR PHARMACOLOGY
- Drugging SUMOylation for neuroprotection and oncotherapy
- (2018) JoshuaD Bernstock et al. Neural Regeneration Research
- HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein
- (2018) Thomas Maurin et al. NUCLEIC ACIDS RESEARCH
- Extranuclear SUMOylation in Neurons
- (2018) Jeremy M. Henley et al. TRENDS IN NEUROSCIENCES
- Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation
- (2018) Anouar Khayachi et al. Nature Communications
- PRMT5-mediated regulation of developmental myelination
- (2018) Antonella Scaglione et al. Nature Communications
- New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons
- (2018) Sara Castagnola et al. Frontiers in Molecular Neuroscience
- PTMD: A Database of Human Disease-associated Post-translational Modifications
- (2018) Haodong Xu et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Post-translational modifications of Parkinson's disease-related proteins: Phosphorylation, SUMOylation and Ubiquitination
- (2018) Stella C. Junqueira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Intragenic FMR1 disease-causing variants: a significant mutational mechanism leading to Fragile-X syndrome
- (2017) Angélique Quartier et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Arginine Methylation: The Coming of Age
- (2017) Roméo S. Blanc et al. MOLECULAR CELL
- Multifarious Functions of the Fragile X Mental Retardation Protein
- (2017) Jenna K. Davis et al. TRENDS IN GENETICS
- Fragile X syndrome
- (2017) Randi J. Hagerman et al. Nature Reviews Disease Primers
- A Small-Molecule Microarray Approach for the Identification of E2 Enzyme Inhibitors in Ubiquitin-Like Conjugation Pathways
- (2017) Katherine Zlotkowski et al. SLAS Discovery
- Topotecan is a potent inhibitor of SUMOylation in glioblastoma multiforme and alters both cellular replication and metabolic programming
- (2017) Joshua D. Bernstock et al. Scientific Reports
- Splice form-dependent regulation of axonal arbor complexity by FMRP
- (2016) Stephanie E. Zimmer et al. Developmental Neurobiology
- Synaptic Actin Dysregulation, a Convergent Mechanism of Mental Disorders?
- (2016) Zhen Yan et al. JOURNAL OF NEUROSCIENCE
- Bidirectional regulation of fragile X mental retardation protein phosphorylation controls rhodopsin homoeostasis
- (2016) Xiao Wang et al. Journal of Molecular Cell Biology
- MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome
- (2016) Derek J. C. Tai et al. Nature Communications
- Targeting the SUMO pathway for neuroprotection in brain ischaemia
- (2016) Wei Yang et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System
- (2015) Misuzu Hashimoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation
- (2015) Joshua D Bernstock et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Systematic investigation of hierarchical phosphorylation by protein kinase CK2
- (2015) Nicole St-Denis et al. Journal of Proteomics
- A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain
- (2015) Ju Huang et al. NEURON
- Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back
- (2015) Christina Gross et al. Neurotherapeutics
- The FMRP/GRK4mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum
- (2015) Thomas Maurin et al. NUCLEIC ACIDS RESEARCH
- Independent role for presynaptic FMRP revealed by anFMR1missense mutation associated with intellectual disability and seizures
- (2015) Leila K. Myrick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PRMT1 and PRMT8 Regulate Retinoic Acid-Dependent Neuronal Differentiation with Implications to Neuropathology
- (2015) Zoltan Simandi et al. STEM CELLS
- SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation
- (2015) Leo T. -H. Tang et al. Nature Communications
- The amino-terminal structure of human fragile X mental retardation protein obtained using precipitant-immobilized imprinted polymers
- (2015) Yufeng Hu et al. Nature Communications
- Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
- (2015) Changwon Kho et al. Nature Communications
- Advances in the development of SUMO specific protease (SENP) inhibitors
- (2015) Ashutosh Kumar et al. Computational and Structural Biotechnology Journal
- Regulation of fragile X mental retardation 1 protein by C-terminus of Hsc70-interacting protein depends on its phosphorylation status
- (2014) Ye Na Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response
- (2014) Roman Alpatov et al. CELL
- Fragile X syndrome due to a missense mutation
- (2014) Leila K Myrick et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain
- (2014) Leila K. Myrick et al. HUMAN MOLECULAR GENETICS
- Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata
- (2014) Misao Takemoto et al. JOURNAL OF ANTIBIOTICS
- The design and delivery of a PKA inhibitory polypeptide to treat SCA1
- (2014) Scoty M. Hearst et al. JOURNAL OF NEUROCHEMISTRY
- Point mutation frequency in the FMR1 gene as revealed by fragile X syndrome screening
- (2014) Maximilian Handt et al. MOLECULAR AND CELLULAR PROBES
- KCNC3R420H, a K+ channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking
- (2014) Carolina Gallego-Iradi et al. NEUROBIOLOGY OF DISEASE
- GABAAergic stimulation modulates intracellular protein arginine methylation
- (2014) Robert B. Denman et al. NEUROSCIENCE LETTERS
- FMRP S499 Is Phosphorylated Independent of mTORC1-S6K1 Activity
- (2014) Christopher M. Bartley et al. PLoS One
- The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
- (2014) Thomas E. Chater et al. Frontiers in Cellular Neuroscience
- mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines
- (2014) Céline Loriol et al. Nature Communications
- Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density
- (2014) Laurent Ferron et al. Nature Communications
- An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation
- (2013) Yeong Sang Kim et al. CHEMISTRY & BIOLOGY
- ACMG Standards and Guidelines for fragile X testing: a revision to the disease-specific supplements to the Standards and Guidelines for Clinical Genetics Laboratories of the American College of Medical Genetics and Genomics
- (2013) Kristin G. Monaghan et al. GENETICS IN MEDICINE
- The translation of translational control by FMRP: therapeutic targets for FXS
- (2013) Jennifer C Darnell et al. NATURE NEUROSCIENCE
- From FMRP Function to Potential Therapies for Fragile X Syndrome
- (2013) Ferzin Sethna et al. NEUROCHEMICAL RESEARCH
- Protein Sumoylation in Brain Development, Neuronal Morphology and Spinogenesis
- (2013) Carole Gwizdek et al. NEUROMOLECULAR MEDICINE
- Contrast, motion, perceptual integration, and neurocognition in schizophrenia: The role of fragile-X related mechanisms
- (2013) Oguz Kelemen et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The next level of complexity: Crosstalk of posttranslational modifications
- (2013) A. Saskia Venne et al. PROTEOMICS
- Decreased fragile X mental retardation protein (FMRP) is associated with lower IQ and earlier illness onset in patients with schizophrenia
- (2013) Tamás Kovács et al. PSYCHIATRY RESEARCH
- Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling
- (2013) Øyvind G Rustan et al. Molecular Autism
- Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?
- (2013) Talakad G Lohith et al. Molecular Autism
- The FMRP regulon: from targets to disease convergence
- (2013) Esperanza Fernández et al. Frontiers in Neuroscience
- Activity-dependent regulation of the sumoylation machinery in rat hippocampal neurons
- (2012) Céline Loriol et al. BIOLOGY OF THE CELL
- Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4
- (2012) S. S. Dhar et al. GENES & DEVELOPMENT
- Evidence for a Fragile X Mental Retardation Protein-Mediated Translational Switch in Metabotropic Glutamate Receptor-Triggered Arc Translation and Long-Term Depression
- (2012) F. Niere et al. JOURNAL OF NEUROSCIENCE
- Dephosphorylation-Induced Ubiquitination and Degradation of FMRP in Dendrites: A Role in Immediate Early mGluR-Stimulated Translation
- (2012) V. C. Nalavadi et al. JOURNAL OF NEUROSCIENCE
- Developmental Regulation and Spatiotemporal Redistribution of the Sumoylation Machinery in the Rat Central Nervous System
- (2012) Céline Loriol et al. PLoS One
- Metabotropic Glutamate Receptor 5 Upregulation in Children with Autism is Associated with Underexpression of Both Fragile X Mental Retardation Protein and GABAA Receptor Beta 3 in Adults with Autism
- (2011) S. Hossein Fatemi et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
- (2011) Jennifer C. Darnell et al. CELL
- In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation
- (2011) R. L. Coffee et al. HUMAN MOLECULAR GENETICS
- Type II Arginine Methyltransferase PRMT5 Regulates Gene Expression of Inhibitors of Differentiation/DNA Binding Id2 and Id4 during Glial Cell Differentiation
- (2011) Jinghan Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual Regulation of Fragile X Mental Retardation Protein by Group I Metabotropic Glutamate Receptors Controls Translation-Dependent Epileptogenesis in the Hippocampus
- (2011) W. Zhao et al. JOURNAL OF NEUROSCIENCE
- Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling
- (2011) Ravi S. Muddashetty et al. MOLECULAR CELL
- Fragile balance: RNA editing tunes the synapse
- (2011) Gary J Bassell NATURE NEUROSCIENCE
- Post-translational modifications of tau protein: Implications for Alzheimer's disease
- (2011) Ludovic Martin et al. NEUROCHEMISTRY INTERNATIONAL
- Routes, destinations and delays: recent advances in AMPA receptor trafficking
- (2011) Jeremy M. Henley et al. TRENDS IN NEUROSCIENCES
- Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study
- (2011) S Hossein Fatemi et al. Molecular Autism
- Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males
- (2010) Stephen C. Collins et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA
- (2010) E. Blackwell et al. HUMAN MOLECULAR GENETICS
- Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome
- (2010) J. L. Olmos-Serrano et al. JOURNAL OF NEUROSCIENCE
- Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132
- (2010) Dieter Edbauer et al. NEURON
- Array-Based FMR1 Sequencing and Deletion Analysis in Patients with a Fragile X Syndrome–Like Phenotype
- (2010) Stephen C. Collins et al. PLoS One
- Fragile X mental retardation protein levels are decreased in major psychiatric disorders
- (2010) S. Hossein Fatemi et al. SCHIZOPHRENIA RESEARCH
- Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate
- (2009) Isao Fukuda et al. CHEMISTRY & BIOLOGY
- Kerriamycin B inhibits protein SUMOylation
- (2009) Isao Fukuda et al. JOURNAL OF ANTIBIOTICS
- A Review of Fragile X Premutation Disorders
- (2009) James A. Bourgeois et al. JOURNAL OF CLINICAL PSYCHIATRY
- Phosphorylation of ATXN1 at Ser776 in the cerebellum
- (2009) Nathan D. Jorgensen et al. JOURNAL OF NEUROCHEMISTRY
- Protein Arginine Methylation in Mammals: Who, What, and Why
- (2009) Mark T. Bedford et al. MOLECULAR CELL
- Phosphorylation of FMRP inhibits association with Dicer
- (2009) A. Cheever et al. RNA
- A Novel Function for Fragile X Mental Retardation Protein in Translational Activation
- (2009) Elias G Bechara et al. PLOS BIOLOGY
- A Mouse Model of the Human Fragile X Syndrome I304N Mutation
- (2009) Julie B. Zang et al. PLoS Genetics
- Chemical and Structural Probing of the N-Terminal Residues Encoded byFMR1Exon 15 and Their Effect on Downstream Arginine Methylation†
- (2008) Natalia Dolzhanskaya et al. BIOCHEMISTRY
- The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP
- (2008) Ilaria Napoli et al. CELL
- S6K1 Phosphorylates and Regulates Fragile X Mental Retardation Protein (FMRP) with the Neuronal Protein Synthesis-dependent Mammalian Target of Rapamycin (mTOR) Signaling Cascade
- (2008) Usha Narayanan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tuberous sclerosis
- (2008) Paolo Curatolo et al. LANCET
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now