Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens

(2018) Mario Leonardo Squadrito et al.   NATURE METHODS

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Periostin Limits Tumor Response to VEGFA Inhibition

(2018) Ioanna Keklikoglou et al.   Cell Reports

Circulating tumor microparticles promote lung metastasis by reprogramming inflammatory and mechanical niches via a macrophage-dependent pathway

(2018) Huafeng Zhang et al.   Cancer Immunology Research

Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer

(2018) Takanori Kitamura et al.   Frontiers in Immunology

The Inner and Outer Qualities of Extracellular Vesicles for Translational Purposes in Breast Cancer

(2018) Esther Schwich et al.   Frontiers in Immunology

Pathologic Complete Response After Neoadjuvant Chemotherapy and Long-Term Outcomes Among Young Women With Breast Cancer

(2017) Laura Spring et al.   Journal of the National Comprehensive Cancer Network

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

(2017) Jan Van Deun et al.   NATURE METHODS

Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer

(2017) Angela DeMichele et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stress-inducible geneAtf3in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis

(2017) Yi Seok Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

(2017) Akira Yokoi et al.   Nature Communications

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity

(2016) Chiara Cianciaruso et al.   DIABETES

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness

(2016) Julie Leca et al.   JOURNAL OF CLINICAL INVESTIGATION

The biology and function of exosomes in cancer

(2016) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Balancing efficacy of and host immune responses to cancer therapy: the yin and yang effects

(2016) Yuval Shaked   Nature Reviews Clinical Oncology

2016 update of the PRIDE database and its related tools

(2016) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neoadjuvant Therapy for Breast Cancer

(2015) Dimitrios Zardavas et al.   Annual Review of Medicine

Inhibition of Oncogenic Epidermal Growth Factor Receptor Kinase Triggers Release of Exosome-like Extracellular Vesicles and Impacts Their Phosphoprotein and DNA Content

(2015) Laura Montermini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

(2015) Takanori Kitamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Specific chemotherapeutic agents induce metastatic behaviour through stromal- and tumour-derived cytokine and angiogenic factor signalling

(2015) Guanghua Liu et al.   JOURNAL OF PATHOLOGY

Blocking IL1  Pathway Following Paclitaxel Chemotherapy Slightly Inhibits Primary Tumor Growth but Promotes Spontaneous Metastasis

(2015) T. Voloshin et al.   MOLECULAR CANCER THERAPEUTICS

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Role of annexin A6 in cancer

(2015) HOUBAO QI et al.   Oncology Letters

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

(2015) A. S. Harney et al.   Cancer Discovery

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth

(2014) Kshitij Srivastava et al.   CANCER CELL

Paclitaxel Therapy Promotes Breast Cancer Metastasis in a TLR4-Dependent Manner

(2014) L. Volk-Draper et al.   CANCER RESEARCH

Quantitative Mass Spectrometry Reveals Plasticity of Metabolic Networks inMycobacterium smegmatis

(2014) Tarun Chopra et al.   MOLECULAR & CELLULAR PROTEOMICS

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

(2014) Laura Bonapace et al.   NATURE

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

Annexin A6 Interacts With p65 and Stimulates NF-κB Activity and Catabolic Events in Articular Chondrocytes

(2013) Kirk A. Campbell et al.   ARTHRITIS AND RHEUMATISM

Evaluating human cancer cell metastasis in zebrafish

(2013) Yong Teng et al.   BMC CANCER

Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

(2013) Sachie Hiratsuka et al.   Nature Communications

Neoadjuvant Chemotherapy and Targeted Therapy in Breast Cancer: Past, Present, and Future

(2013) Simon P. Gampenrieder et al.   Journal of Oncology

Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance

(2012) Elizabeth S. Nakasone et al.   CANCER CELL

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Chemotherapy Enhances Metastasis Formation via VEGFR-1-Expressing Endothelial Cells

(2011) L. G. M. Daenen et al.   CANCER RESEARCH

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish

(2011) Caroline Gray et al.   THROMBOSIS AND HAEMOSTASIS

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions

(2010) Amos M. Sakwe et al.   EXPERIMENTAL CELL RESEARCH

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Preoperative Chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27

(2008) Priya Rastogi et al.   JOURNAL OF CLINICAL ONCOLOGY