Recent advances in protein hydrogels: From design, structural and functional regulations to healthcare applications

Wound Microenvironment-Responsive Protein Hydrogel Drug-Loaded System with Accelerating Healing and Antibacterial Property

(2022) Rong Zhang et al.   ACS Applied Materials & Interfaces

Synergistic complexation of phenol functionalized polymer induced in situ microfiber formation for 3D printing of marine-based hydrogels

(2022) Hafez Jafari et al.   GREEN CHEMISTRY

Fibrous Structure and Stiffness of Designer Protein Hydrogels Synergize to Regulate Endothelial Differentiation of Bone Marrow Mesenchymal Stem Cells

(2022) Kai-Kai Tian et al.   BIOMACROMOLECULES

Magnetic-responsive polysaccharide hydrogels as smart biomaterials: Synthesis, properties, and biomedical applications

(2022) Elizângela H. Fragal et al.   CARBOHYDRATE POLYMERS

Design of functional hydrogels using smart polymer based on elastin-like polypeptides

(2022) Zhongwei Guo et al.   CHEMICAL ENGINEERING JOURNAL

Sustained gene delivery from inflammation-responsive anti-inflammatory hydrogels promotes extracellular matrix metabolism balance in degenerative nucleus pulposus

(2022) Yu Wang et al.   COMPOSITES PART B-ENGINEERING

Preparation and characterization of a novel antibacterial hydrogel based on thiolated ovalbumin/gelatin with silver ions

(2022) Yue Chen et al.   Innovative Food Science & Emerging Technologies

Fabrication of heteroatom-self-doped hierarchical porous carbon from soy protein isolate hydrogel for high-performance supercapacitors via a double-effect strategy of template-activation

(2022) Jinhuan Li et al.   MICROPOROUS AND MESOPOROUS MATERIALS

A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms

(2022) Jiang Ouyang et al.   Bioactive Materials

Protein Nanofibrils and Their Hydrogel Formation with Metal Ions

(2021) Xinchen Ye et al.   ACS Nano

Dual Cross-Linked Organic-inorganic Hybrid Hydrogels Accelerate Diabetic Skin Wound Healing

(2021) Yuna Qian et al.   CHEMICAL ENGINEERING JOURNAL

Injectable cuttlefish HAP and macromolecular fibroin protein hydrogel for natural bone mimicking matrix for enhancement of osteoinduction progression

(2021) Mukherjee Arjama et al.   REACTIVE & FUNCTIONAL POLYMERS

Engineered Protein Photo‐Thermal Hydrogels for Outstanding In Situ Tongue Cancer Therapy

(2021) Juanjuan Su et al.   ADVANCED MATERIALS

Electrical stimulation of neonatal rat cardiomyocytes using conductive polydopamine-reduced graphene oxide-hybrid hydrogels for constructing cardiac microtissues

(2021) Xiao-Pei Li et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Research progress on polysaccharide/protein hydrogels: Preparation method, functional property and application as delivery systems for bioactive ingredients

(2021) Kang Liu et al.   FOOD RESEARCH INTERNATIONAL

Protein–Polymer Interaction Characteristics Unique to Nanoscale Interfaces: A Perspective on Recent Insights

(2021) David H. Cho et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Light-Responsive Dynamic Protein Hydrogels Based on LOVTRAP

(2021) Tianyu Duan et al.   LANGMUIR

Enzyme-Loaded pH-Sensitive Photothermal Hydrogels for Mild-temperature-mediated Combinational Cancer Therapy

(2021) Jindong Xia et al.   Frontiers in Chemistry

Amino Acids, Peptides, and Proteins: Implications for Nanotechnological Applications in Biosensing and Drug/Gene Delivery

(2021) Simge Er et al.   Nanomaterials

Biomass vs inorganic and plastic-based aerogels: Structural design, functional tailoring, resource-efficient applications and sustainability analysis

(2021) Gang Wei et al.   PROGRESS IN MATERIALS SCIENCE

Temperature-Responsive Multifunctional Protein Hydrogels with Elastin-like Polypeptides for 3-D Angiogenesis

(2020) Yoshinori Mizuguchi et al.   BIOMACROMOLECULES

Tunable Biomimetic Hydrogels from Silk Fibroin and Nanocellulose

(2020) Pramod Dorishetty et al.   ACS Sustainable Chemistry & Engineering

A Skin‐Inspired, Interactive, and Flexible Optoelectronic Device with Hydrated Melanin Nanoparticles in a Protein Hydrogel–Elastomer Hybrid

(2020) Narendar Gogurla et al.   Advanced Materials Technologies

Injectable Polypeptide‐Protein Hydrogels for Promoting Infected Wound Healing

(2020) Liang Cheng et al.   ADVANCED FUNCTIONAL MATERIALS

Protein Gel's Phase Transition: Toward Superiorly Transparent and Hysteresis‐Free Wearable Electronics

(2020) Qiang Chang et al.   ADVANCED FUNCTIONAL MATERIALS

Carbon nanotube-integrated conductive hydrogels as multifunctional robotic skin

(2020) Li-Yin Hsiao et al.   CARBON

100th Anniversary of Macromolecular Science Viewpoint: Synthetic Protein Hydrogels

(2020) Ying Li et al.   ACS Macro Letters

Hydrogels and Hydrogel-Derived Materials for Energy and Water Sustainability

(2020) Youhong Guo et al.   CHEMICAL REVIEWS

A novel bovine serum albumin and sodium alginate hydrogel scaffold doped with hydroxyapatite nanowires for cartilage defects repair

(2020) Huifang Yuan et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Recent trends in peptide and protein-based hydrogels

(2020) Priya Katyal et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Fabrication and characterization of cold-gelation whey protein-chitosan complex hydrogels for the controlled release of curcumin

(2020) Zhuzhu Liu et al.   FOOD HYDROCOLLOIDS

“All-in-one” hydrolyzed keratin protein-modified polyacrylamide composite hydrogel transducer

(2020) Yang Gao et al.   CHEMICAL ENGINEERING JOURNAL

Diverse mechanical properties and microstructures of sorghum bran arabinoxylans/soy protein isolate mixed gels by duo-induction of peroxidase and calcium ions

(2020) Jinxin Yan et al.   FOOD HYDROCOLLOIDS

Entrapment of curcumin in whey protein isolate and zein composite nanoparticles using pH-driven method

(2020) Xinyu Zhan et al.   FOOD HYDROCOLLOIDS

Corn fiber gum-soybean protein isolate double network hydrogel as oral delivery vehicles for thermosensitive bioactive compounds

(2020) Wenjia Yan et al.   FOOD HYDROCOLLOIDS

Porous hydrogels templated from soy-protein-stabilized high internal phase emulsions

(2020) Xuehui Gong et al.   Journal of Materials Science

Fluorescent Noble Metal Nanoclusters Loaded Protein Hydrogel Exhibiting Anti‐Biofouling and Self‐Healing Properties for Electrochemiluminescence Biosensing Applications

(2020) Cuiyan Han et al.   Small

Injectable, photoresponsive hydrogels for delivering neuroprotective proteins enabled by metal-directed protein assembly

(2020) Bojing Jiang et al.   Science Advances

Dynamically tunable light responsive silk-elastin-like proteins

(2020) Om Prakash Narayan et al.   Acta Biomaterialia

High‐Preservation Single‐Cell Operation through a Photo‐responsive Hydrogel‐Nanopipette System

(2020) Zi‐Yuan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effects of Biotin-Avidin Interactions on Hydrogel Swelling

(2020) Talaial B. Alina et al.   Frontiers in Chemistry

Hybrid gelatin/oxidized chondroitin sulfate hydrogels incorporating bioactive glass nanoparticles with enhanced mechanical properties, mineralization, and osteogenic differentiation

(2020) Lei Zhou et al.   Bioactive Materials

Protein hydrogel networks: A unique approach to heteroatom self-doped hierarchically porous carbon structures as an efficient ORR electrocatalyst in both basic and acidic conditions

(2019) Liqiang Wang et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

Graphene oxide-based hydrogels as a nanocarrier for anticancer drug delivery

(2019) Abdullah A. Ghawanmeh et al.   Nano Research

Design of Self-Healing and Electrically Conductive Silk Fibroin-Based Hydrogels

(2019) Lichao Liu et al.   ACS Applied Materials & Interfaces

Salt‐Assisted Toughening of Protein Hydrogel with Controlled Degradation for Bone Regeneration

(2019) Li‐Bo Jiang et al.   ADVANCED FUNCTIONAL MATERIALS

Robust, highly porous hydrogels templated within emulsions stabilized using a reactive, crosslinking triblock copolymer

(2019) Tao Zhang et al.   POLYMER

Robust and Tunable Hybrid Hydrogels from Photo-Cross-Linked Soy Protein Isolate and Regenerated Silk Fibroin

(2019) Pramod Dorishetty et al.   ACS Sustainable Chemistry & Engineering

Thermoresponsive Protein-Engineered Coiled-coil Hydrogel for Sustained Small Molecule Release

(2019) Lindsay K. Hill et al.   BIOMACROMOLECULES

Thermoresponsive in Situ Forming Hydrogel with Sol–Gel Irreversibility for Effective Methicillin-Resistant Staphylococcus aureus Infected Wound Healing

(2019) Xu Yan et al.   ACS Nano

pH-Switchable Antimicrobial Nanofiber Networks of Hydrogel Eradicate Biofilm and Rescue Stalled Healing in Chronic Wounds

(2019) Jianhao Wang et al.   ACS Nano

Nanoparticle-Based Hybrid Scaffolds for Deciphering the Role of Multimodal Cues in Cardiac Tissue Engineering

(2019) Junmin Lee et al.   ACS Nano

An Injectable Self-Healing Protein Hydrogel with Multiple Dissipation Modes and Tunable Dynamic Response

(2019) Wenxu Sun et al.   BIOMACROMOLECULES

Characterization and embedding potential of bovine serum albumin cold-set gel induced by glucono-δ-lactone and sodium chloride

(2019) Xiao-min Chen et al.   FOOD HYDROCOLLOIDS

Polymeric DNA hydrogel: Design, synthesis and applications

(2019) Feng Li et al.   PROGRESS IN POLYMER SCIENCE

Chemical unfolding of protein domains induces shape change in programmed protein hydrogels

(2019) Luai R. Khoury et al.   Nature Communications

Highly sensitive three-dimensional interdigitated microelectrode biosensors embedded with porosity tunable hydrogel for detecting proteins

(2019) Hye Jin Kim et al.   SENSORS AND ACTUATORS B-CHEMICAL

Protein and Hydrophobic Association‐Regulated Hydrogels with Adhesive Adjustability in Different Materials

(2019) Jianyu Xu et al.   Advanced Materials Interfaces

Enzymatic Formation of an Injectable Hydrogel from a Glycopeptide as a Biomimetic Scaffold for Vascularization

(2018) Jingjing Qi et al.   ACS Applied Materials & Interfaces

Protein-Based Electronic Skin Akin to Biological Tissues

(2018) Minsik Jo et al.   ACS Nano

Silk fibroin/collagen protein hybrid cell-encapsulating hydrogels with tunable gelation and improved physical and biological properties

(2018) Jennifer O. Buitrago et al.   Acta Biomaterialia

Protein Engineered Triblock Polymers Composed of Two SADs: Enhanced Mechanical Properties and Binding Abilities

(2018) Andrew J. Olsen et al.   BIOMACROMOLECULES

Programmable hydrogels

(2018) Yong Wang   BIOMATERIALS

Dynamic Protein-Metal Ion Networks: A Unique Approach to Injectable and Self-Healable Metal Sulfide/Protein Hybrid Hydrogels with High Photothermal Efficiency

(2018) Liqiang Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rheological properties and microstructure of soy-whey protein

(2018) Thu H. McCann et al.   FOOD HYDROCOLLOIDS

Hydrogel matrices based on elastin and alginate for tissue engineering applications

(2018) Raquel Silva et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers

(2018) Liping Sun et al.   International Journal of Nanomedicine

Protein-engineered hydrogels enhance the survival of induced pluripotent stem cell-derived endothelial cells for treatment of peripheral arterial disease

(2018) Abbygail A. Foster et al.   Biomaterials Science

Tuneable hydrogels of Caf1 protein fibers

(2018) Gema Dura et al.   Materials Science & Engineering C-Materials for Biological Applications

A Robust, Resilient, and Multi-Functional Soy Protein-Based Hydrogel

(2018) Jialin Liu et al.   ACS Sustainable Chemistry & Engineering

Chitosan–Lysozyme Conjugates for Enzyme-Triggered Hydrogel Degradation in Tissue Engineering Applications

(2018) Soyon Kim et al.   ACS Applied Materials & Interfaces

General Principle for Fabricating Natural Globular Protein-Based Double-Network Hydrogels with Integrated Highly Mechanical Properties and Surface Adhesion on Solid Surfaces

(2018) Ziqing Tang et al.   CHEMISTRY OF MATERIALS

Preparation, characterization and application of a protein hydrogel with rapid self-healing and unique autofluoresent multi-functionalities

(2018) Jun Chen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Multi-triggered Supramolecular DNA/Bipyridinium Dithienylethene Hydrogels Driven by Light, Redox, and Chemical Stimuli for Shape-Memory and Self-Healing Applications

(2018) Ziyuan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revisiting the insights and applications of protein engineered hydrogels

(2018) Brindha J. et al.   Materials Science & Engineering C-Materials for Biological Applications

The formation of non-heat-treated whey protein cold-set hydrogels via non-toxic chemical cross-linking

(2017) Arash Abaee et al.   FOOD HYDROCOLLOIDS

Development of iron-rich whey protein hydrogels following application of ohmic heating – Effects of moderate electric fields

(2017) Ricardo N. Pereira et al.   FOOD RESEARCH INTERNATIONAL

One-pot synthesis of soy protein (SP)-poly(acrylic acid) (PAA) superabsorbent hydrogels via facile preparation of SP macromonomer

(2017) Wenjia Song et al.   INDUSTRIAL CROPS AND PRODUCTS

Construction and characterization of a pure protein hydrogel for drug delivery application

(2017) Xu Xu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Artificial Auricular Cartilage Using Silk Fibroin and Polyvinyl Alcohol Hydrogel

(2017) Jung Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogel based approaches for cardiac tissue engineering

(2017) Laura Saludas et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Whey and soy protein-based hydrogels and nano-hydrogels as bioactive delivery systems

(2017) Arash Abaee et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Hydrogel Based Biosensors for In Vitro Diagnostics of Biochemicals, Proteins, and Genes

(2017) Il Young Jung et al.   Advanced Healthcare Materials

Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein-DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity

(2017) Jasmina Gačanin et al.   Advanced Healthcare Materials

Antitumor Photodynamic Therapy Based on Dipeptide Fibrous Hydrogels with Incorporation of Photosensitive Drugs

(2017) Manzar Abbas et al.   ACS Biomaterials-Science & Engineering

Antitumor Photodynamic Therapy Based on Dipeptide Fibrous Hydrogels with Incorporation of Photosensitive Drugs

(2017) Manzar Abbas et al.   ACS Biomaterials Science & Engineering

Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment

(2017) Lan Huong Nguyen et al.   Scientific Reports

Injectable and pH-Responsive Silk Nanofiber Hydrogels for Sustained Anticancer Drug Delivery

(2016) Hongchun Wu et al.   ACS Applied Materials & Interfaces

An injectable silk sericin hydrogel promotes cardiac functional recovery after ischemic myocardial infarction

(2016) Yu Song et al.   Acta Biomaterialia

Bio-Orthogonally Crosslinked, Engineered Protein Hydrogels with Tunable Mechanics and Biochemistry for Cell Encapsulation

(2016) Christopher M. Madl et al.   ADVANCED FUNCTIONAL MATERIALS

Enzyme-Catalyzed Formation of Supramolecular Hydrogels as Promising Vaccine Adjuvants

(2016) Huaimin Wang et al.   ADVANCED FUNCTIONAL MATERIALS

An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy

(2016) Ruirui Xing et al.   ADVANCED MATERIALS

Rationally Designed Redox-Sensitive Protein Hydrogels with Tunable Mechanical Properties

(2016) Ming-Liang Zhou et al.   BIOMACROMOLECULES

Engineering Protein Hydrogels Using SpyCatcher-SpyTag Chemistry

(2016) Xiaoye Gao et al.   BIOMACROMOLECULES

A new strategy for fabrication of bone scaffolds using electrospun nano-HAp/PHB fibers and protein hydrogels

(2016) Mehdi Sadat-Shojai et al.   CHEMICAL ENGINEERING JOURNAL

Swelling of whey and egg white protein hydrogels with stranded and particulate microstructures

(2016) Hui Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Stimuli-Sensitive Injectable Hydrogels Based on Polysaccharides and Their Biomedical Applications

(2016) Thavasyappan Thambi et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Photonic crystal protein hydrogel sensor materials enabled by conformationally induced volume phase transition

(2016) Zhongyu Cai et al.   Chemical Science

A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Autofluorescence: Preparation, Characterization and In Vivo Biodegradation Tracking and Modeling

(2016) Xiaoyu Ma et al.   Scientific Reports

Repetitive Biomimetic Self-healing of Ca2+-Induced Nanocomposite Protein Hydrogels

(2016) Jun Chen et al.   Scientific Reports

Emerging hydrogel designs for controlled protein delivery

(2016) Ki Hyun Bae et al.   Biomaterials Science

Metal Chelation Dynamically Regulates the Mechanical Properties of Engineered Protein Hydrogels

(2016) Na Kong et al.   ACS Biomaterials-Science & Engineering

Metal Chelation Dynamically Regulates the Mechanical Properties of Engineered Protein Hydrogels

(2016) Na Kong et al.   ACS Biomaterials Science & Engineering

Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels

(2015) Nasim Annabi et al.   ADVANCED MATERIALS

A Photonic Crystal Protein Hydrogel Sensor forCandida albicans

(2015) Zhongyu Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoclick Hydrogels Prepared from Functionalized Cyclodextrin and Poly(ethylene glycol) for Drug Delivery and in Situ Cell Encapsulation

(2015) Han Shih et al.   BIOMACROMOLECULES

Characteristics of the bulk hydrogels made of the citric acid cross-linked whey protein microgels

(2015) Toktam Farjami et al.   FOOD HYDROCOLLOIDS

Water holding capacity and swelling of casein hydrogels

(2015) C.G. (Kees) de Kruif et al.   FOOD HYDROCOLLOIDS

Low-temperature crosslinking of proteins using non-toxic citric acid in neutral aqueous medium: Mechanism and kinetic study

(2015) Helan Xu et al.   INDUSTRIAL CROPS AND PRODUCTS

Design and performance of a sericin-alginate interpenetrating network hydrogel for cell and drug delivery

(2015) Yeshun Zhang et al.   Scientific Reports

Amyloid-Hydroxyapatite Bone Biomimetic Composites

(2014) Chaoxu Li et al.   ADVANCED MATERIALS

2D Photonic Crystal Protein Hydrogel Coulometer for Sensing Serum Albumin Ligand Binding

(2014) Zhongyu Cai et al.   ANALYTICAL CHEMISTRY

Albumin Hydrogels Formed by Electrostatically Triggered Self-Assembly and Their Drug Delivery Capability

(2014) Kevin Baler et al.   BIOMACROMOLECULES

Synthesis and properties of canola protein-based superabsorbent hydrogels

(2014) Weida Shi et al.   EUROPEAN POLYMER JOURNAL

Cold-set whey protein microgels as pH modulated immobilisation matrices for charged bioactives

(2014) Thelma Egan et al.   FOOD CHEMISTRY

Nanoencapsulation of food ingredients using carbohydrate based delivery systems

(2014) Milad Fathi et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Synthesis and characterization of citric acid-based pH-sensitive biopolymeric hydrogels

(2013) D. S. Franklin et al.   POLYMER BULLETIN

An injectable drug delivery platform for sustained combination therapy

(2009) M. Douglas Baumann et al.   JOURNAL OF CONTROLLED RELEASE

Enzyme-Catalyzed Formation and Structure Characteristics of A Protein-Based Hydrogel

(2008) Fei Song et al.   JOURNAL OF PHYSICAL CHEMISTRY B