The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
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Title
The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
Authors
Keywords
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Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-10-28
DOI
10.1038/s41467-022-34078-y
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Note: Only part of the references are listed.- METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
- (2022) Rui Su et al. NATURE CELL BIOLOGY
- Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing
- (2021) Mateusz Mendel et al. CELL
- mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
- (2021) Elodie Villa et al. MOLECULAR CELL
- m 6 A‐mediated alternative splicing coupled with nonsense‐mediated mRNA decay regulates SAM synthetase homeostasis
- (2021) Eichi Watabe et al. EMBO JOURNAL
- Genetic drivers of m6A methylation in human brain, lung, heart and muscle
- (2021) Xushen Xiong et al. NATURE GENETICS
- A single m6A modification in U6 snRNA diversifies exon sequence at the 5’ splice site
- (2021) Yuma Ishigami et al. Nature Communications
- N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
- (2020) Jun Liu et al. SCIENCE
- Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9
- (2020) Emily C. Freund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The RNA modification N6-methyladenosine as a novel regulator of the immune system
- (2020) Ziv Shulman et al. NATURE IMMUNOLOGY
- Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids
- (2020) Eva Bartok et al. IMMUNITY
- IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences
- (2019) Kristoffer Vitting-Seerup et al. BIOINFORMATICS
- Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1
- (2019) Sylwia D. Tyrkalska et al. IMMUNITY
- Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
- (2019) Daehwan Kim et al. NATURE BIOTECHNOLOGY
- Reading, writing and erasing mRNA methylation
- (2019) Sara Zaccara et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues
- (2019) Jun’e Liu et al. MOLECULAR CELL
- N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
- (2019) Daniel A. Kuppers et al. Nature Communications
- Regulation of cGAS- and RLR-mediated immunity to nucleic acids
- (2019) Andrea Ablasser et al. NATURE IMMUNOLOGY
- Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
- (2018) Rajiv K. Khajuria et al. CELL
- Transferrin and transferrin receptors update
- (2018) Hiroshi Kawabata FREE RADICAL BIOLOGY AND MEDICINE
- The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
- (2018) Tuo Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A brave new world of RNA-binding proteins
- (2018) Matthias W. Hentze et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk
- (2018) De-Liang Zhang et al. SCIENCE
- Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress
- (2018) De-Liang Zhang et al. BLOOD
- Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor
- (2018) Katelyn A. Doxtader et al. MOLECULAR CELL
- Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development
- (2018) Mateusz Mendel et al. MOLECULAR CELL
- Population snapshots predict early haematopoietic and erythroid hierarchies
- (2018) Betsabeh Khoramian Tusi et al. NATURE
- An Elongation- and Ligation-Based qPCR Amplification Method for the Radiolabeling-Free Detection of Locus-Specific N 6 -Methyladenosine Modification
- (2018) Yu Xiao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors
- (2017) John C. Zinder et al. GENES & DEVELOPMENT
- The transferrin receptor: the cellular iron gate
- (2017) Elena Gammella et al. Metallomics
- Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
- (2017) Kyuho Han et al. NATURE BIOTECHNOLOGY
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- Detecting RNA modifications in the epitranscriptome: predict and validate
- (2017) Mark Helm et al. NATURE REVIEWS GENETICS
- The RNA modification landscape in human disease
- (2017) Nicky Jonkhout et al. RNA
- Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
- (2017) David W. Morgens et al. Nature Communications
- S -Adenosylmethionine Synthesis Is Regulated by Selective N 6 -Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1
- (2017) Hiroki Shima et al. Cell Reports
- Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs
- (2017) Masanori Yoshinaga et al. Cell Reports
- Efficient generation of conditional knockout mice via sequential introduction of lox sites
- (2017) Takuro Horii et al. Scientific Reports
- Advances in understanding erythropoiesis: evolving perspectives
- (2016) Satish K. Nandakumar et al. BRITISH JOURNAL OF HAEMATOLOGY
- Regulation of hematopoietic development by ZBTB transcription factors
- (2016) Takahiro Maeda INTERNATIONAL JOURNAL OF HEMATOLOGY
- Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes
- (2016) David W Morgens et al. NATURE BIOTECHNOLOGY
- Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
- (2016) Richard M Deans et al. Nature Chemical Biology
- The regulation and functions of the nuclear RNA exosome complex
- (2016) Cornelia Kilchert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
- (2016) Alexis Vandenbon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Methyltransferase-like protein 16 binds the 3′-terminal triple helix of MALAT1 long noncoding RNA
- (2016) Jessica A. Brown et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
- (2016) Max A Horlbeck et al. eLife
- Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification
- (2015) Caroline Roost et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iron regulatory proteins and their role in controlling iron metabolism
- (2015) Lukas C. Kühn Metallomics
- N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
- (2015) Nian Liu et al. NATURE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality
- (2015) Silvia Alvarez et al. Nature Communications
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors
- (2014) J Farrés et al. CELL DEATH AND DIFFERENTIATION
- A regulatory network governing Gata1 and Gata2 gene transcription orchestrates erythroid lineage differentiation
- (2014) Takashi Moriguchi et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- A census of human RNA-binding proteins
- (2014) Stefanie Gerstberger et al. NATURE REVIEWS GENETICS
- Primitive and definitive erythropoiesis in mammals
- (2014) James Palis Frontiers in Physiology
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- A systematic analysis of global anemia burden from 1990 to 2010
- (2013) N. J. Kassebaum et al. BLOOD
- DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis
- (2012) Wynand P. Roos et al. CANCER LETTERS
- Detecting differential usage of exons from RNA-seq data
- (2012) S. Anders et al. GENOME RESEARCH
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
- (2011) S. M. Hattangadi et al. BLOOD
- Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex
- (2011) Michal Lubas et al. MOLECULAR CELL
- REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
- (2011) Fran Supek et al. PLoS One
- The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
- (2010) Rafal Tomecki et al. EMBO JOURNAL
- TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
- (2010) John-Demian Sauer et al. INFECTION AND IMMUNITY
- A Key Commitment Step in Erythropoiesis Is Synchronized with the Cell Cycle Clock through Mutual Inhibition between PU.1 and S-Phase Progression
- (2010) Ramona Pop et al. PLOS BIOLOGY
- Oxidative Stress in the Regulation of Normal and Neoplastic Hematopoiesis
- (2008) Saghi Ghaffari ANTIOXIDANTS & REDOX SIGNALING
- Homeostatic erythropoiesis by the transcription factor IRF2 through attenuation of type I interferon signaling
- (2008) T MIZUTANI EXPERIMENTAL HEMATOLOGY
- Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2
- (2008) Peng Ji et al. NATURE CELL BIOLOGY
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