From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes

(2011) P. Wong et al.   BLOOD

Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

(2011) Marloes R. Tijssen et al.   DEVELOPMENTAL CELL

The gata1/pu.1 lineage fate paradigm varies between blood populations and is modulated by tif1γ

(2011) Rui Monteiro et al.   EMBO JOURNAL

LYL-1 deficiency induces a stress erythropoiesis

(2011) Claude Capron et al.   EXPERIMENTAL HEMATOLOGY

miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1

(2011) L. Zhang et al.   GENES & DEVELOPMENT

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

(2011) W. Wu et al.   GENOME RESEARCH

MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

(2011) V. G. Sankaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of mammalian erythrocytes: chromatin condensation and enucleation

(2011) Peng Ji et al.   TRENDS IN CELL BIOLOGY

Early mammalian erythropoiesis requires the Dot1L methyltransferase

(2010) Y. Feng et al.   BLOOD

Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation

(2010) S. Millot et al.   BLOOD

Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture

(2010) S. Singbrant et al.   BLOOD

HIF1  synergizes with glucocorticoids to promote BFU-E progenitor self-renewal

(2010) J. Flygare et al.   BLOOD

Advances in the understanding of haemoglobin switching

(2010) Vijay G. Sankaran et al.   BRITISH JOURNAL OF HAEMATOLOGY

TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation

(2010) Xiaoying Bai et al.   CELL

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Update on fetal hemoglobin gene regulation in hemoglobinopathies

(2010) Daniel E Bauer et al.   CURRENT OPINION IN PEDIATRICS

Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3 

(2010) D. M. Patrick et al.   GENES & DEVELOPMENT

miR-451 protects against erythroid oxidant stress by repressing 14-3-3 

(2010) D. Yu et al.   GENES & DEVELOPMENT

The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation

(2010) E. Soler et al.   GENES & DEVELOPMENT

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells

(2010) M. R. Tallack et al.   GENOME RESEARCH

Genome-wide identification of TAL1's functional targets: Insights into its mechanisms of action in primary erythroid cells

(2010) M. T. Kassouf et al.   GENOME RESEARCH

Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts

(2010) P. Ji et al.   HAEMATOLOGICA

Primitive erythropoiesis in the mammalian embryo

(2010) James Palis et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Down-regulation of Myc Is Essential for Terminal Erythroid Maturation

(2010) Senthil Raja Jayapal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitors

(2010) Omid F. Harandi et al.   JOURNAL OF CLINICAL INVESTIGATION

Networking erythropoiesis: Figure 1.

(2010) Marc A. Kerenyi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The miR-144/451 locus is required for erythroid homeostasis

(2010) Kasper D. Rasmussen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reversing the Hemoglobin Switch

(2010) Vijay G. Sankaran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia Regulates BMP4 Expression in the Murine Spleen during the Recovery from Acute Anemia

(2010) Dai-Chen Wu et al.   PLoS One

Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells

(2010) Song Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Key Commitment Step in Erythropoiesis Is Synchronized with the Cell Cycle Clock through Mutual Inhibition between PU.1 and S-Phase Progression

(2010) Ramona Pop et al.   PLOS BIOLOGY

ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling

(2009) A. D. Wood et al.   BLOOD

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation

(2009) Kairong Cui et al.   Cell Stem Cell

Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation

(2009) Evgenya Y. Popova et al.   CHROMOSOME RESEARCH

LRF Is an Essential Downstream Target of GATA1 in Erythroid Development and Regulates BIM-Dependent Apoptosis

(2009) Takahiro Maeda et al.   DEVELOPMENTAL CELL

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

(2009) Y. Cheng et al.   GENOME RESEARCH

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis

(2009) N. Felli et al.   HAEMATOLOGICA

Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy

(2009) Tohru Fujiwara et al.   MOLECULAR CELL

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis

(2009) Ming Yu et al.   MOLECULAR CELL

Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells

(2009) Stefan Schoenfelder et al.   NATURE GENETICS

Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signaling

(2008) J. M. Perry et al.   BLOOD

EPO receptor circuits for primary erythroblast survival

(2008) P. Sathyanarayana et al.   BLOOD

Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression

(2008) B.-M. Zhu et al.   BLOOD

miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2

(2008) L. Pase et al.   BLOOD

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

(2008) T. Tripic et al.   BLOOD

Mir-144 selectively regulates embryonic  -hemoglobin synthesis during primitive erythropoiesis

(2008) Y.-F. Fu et al.   BLOOD

Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference

(2008) Adrianna Vlachos et al.   BRITISH JOURNAL OF HAEMATOLOGY

Differential H3K4 Methylation Identifies Developmentally Poised Hematopoietic Genes

(2008) Keith Orford et al.   DEVELOPMENTAL CELL

MicroRNA-Mediated Control of Cell Fate in Megakaryocyte-Erythrocyte Progenitors

(2008) Jun Lu et al.   DEVELOPMENTAL CELL

Erythropoietins: A common mechanism of action

(2008) Steve Elliott et al.   EXPERIMENTAL HEMATOLOGY

Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

(2008) V. G. Sankaran et al.   GENES & DEVELOPMENT

A GATA-1-regulated microRNA locus essential for erythropoiesis

(2008) L. C. Dore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4

(2007) Q. Wang et al.   BLOOD