Targeting innate immunity-driven inflammation in CKD and cardiovascular disease
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting innate immunity-driven inflammation in CKD and cardiovascular disease
Authors
Keywords
-
Journal
Nature Reviews Nephrology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-09-05
DOI
10.1038/s41581-022-00621-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genetic IL-6 Signaling Modifies Incident Coronary Artery Disease Risk in Chronic Kidney Disease
- (2022) Zhi Yu et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Kidney and heart failure outcomes associated with SGLT2 inhibitor use
- (2022) Annemarie B. van der Aart-van der Beek et al. Nature Reviews Nephrology
- Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production
- (2022) Marco Orecchioni et al. SCIENCE
- Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease
- (2022) Caitlyn Vlasschaert et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The evolving story of apolipoprotein L1 nephropathy: the end of the beginning
- (2022) Parnaz Daneshpajouhnejad et al. Nature Reviews Nephrology
- TET2-Driven Clonal Hematopoiesis and Response to Canakinumab
- (2022) Eric C. Svensson et al. JAMA Cardiology
- Inflammation drives residual risk in chronic kidney disease: a CANTOS substudy
- (2022) Paul M Ridker et al. EUROPEAN HEART JOURNAL
- Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes
- (2021) Godfrey S. Temba et al. NATURE IMMUNOLOGY
- Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
- (2021) Paul M Ridker et al. CIRCULATION RESEARCH
- Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials
- (2021) Aernoud T L Fiolet et al. EUROPEAN HEART JOURNAL
- Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality
- (2021) Stefan J Schunk et al. EUROPEAN HEART JOURNAL
- Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
- (2021) Kaspar Broch et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Clonal Hematopoiesis and Risk of Progression of Heart Failure With Reduced Left Ventricular Ejection Fraction
- (2021) Domingo A. Pascual-Figal et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial
- (2021) Paul M Ridker et al. LANCET
- The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
- (2021) Trevor P. Fidler et al. NATURE
- Targeting inflammation in atherosclerosis — from experimental insights to the clinic
- (2021) Oliver Soehnlein et al. NATURE REVIEWS DRUG DISCOVERY
- Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair
- (2021) Katie J. Mylonas et al. Science Translational Medicine
- Chronic Inflammation in Chronic Kidney Disease Progression: Role of Nrf2
- (2021) Peter Stenvinkel et al. Kidney International Reports
- Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease
- (2021) Stefan J. Schunk et al. CIRCULATION
- Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis
- (2021) Laurienne Edgar et al. CIRCULATION
- Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis
- (2021) Susana Rocha et al. Scientific Reports
- Chronic stress primes innate immune responses in mice and humans
- (2021) Tessa J. Barrett et al. Cell Reports
- Interleukin 6 and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Chronic Coronary Syndrome
- (2021) Gorav Batra et al. JAMA Cardiology
- Interleukin-1β suppression dampens inflammatory leukocyte production and uptake in atherosclerosis
- (2021) Jan Hettwer et al. CARDIOVASCULAR RESEARCH
- Retention of the NLRP3 Inflammasome–Primed Neutrophils in the Bone Marrow Is Essential for Myocardial Infarction–Induced Granulopoiesis
- (2021) Gopalkrishna Sreejit et al. CIRCULATION
- AIM2 inflammasome contributes to aldosterone-induced renal injury via endoplasmic reticulum stress
- (2021) Yong Wu et al. CLINICAL SCIENCE
- Inflammation and Oxidative Stress in Diabetic Kidney Disease: The Targets for SGLT2 Inhibitors and GLP-1 Receptor Agonists
- (2021) Agata Winiarska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury
- (2021) Stefan J. Schunk et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation
- (2020) Yoshitaka Kimura et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis Following Myocardial Infarction
- (2020) Gopalkrishna Sreejit et al. CIRCULATION
- Effects of Interleukin-1β Inhibition on Incident Anemia
- (2020) Mounica Vallurupalli et al. ANNALS OF INTERNAL MEDICINE
- Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes
- (2020) Friedrich Felix Hoyer et al. CIRCULATION
- Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
- (2020) Antonio Abbate et al. CIRCULATION RESEARCH
- SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease
- (2020) So Ra Kim et al. Nature Communications
- Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement
- (2020) Matthias Schieker et al. ANNALS OF INTERNAL MEDICINE
- Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis
- (2020) Michelle C Flynn et al. CIRCULATION RESEARCH
- Senolytic drugs: from discovery to translation
- (2020) J. L. Kirkland et al. JOURNAL OF INTERNAL MEDICINE
- Myocardial infarction accelerates breast cancer via innate immune reprogramming
- (2020) Graeme J. Koelwyn et al. NATURE MEDICINE
- Podocytopathies
- (2020) Jeffrey B. Kopp et al. Nature Reviews Disease Primers
- Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure
- (2020) Wesley Tyler Abplanalp et al. JAMA Cardiology
- Genetic or Pharmacologic Nrf2 Activation Increases Proteinuria in Chronic Kidney Disease in Mice
- (2020) Brittney M. Rush et al. KIDNEY INTERNATIONAL
- Food as medicine: targeting the uraemic phenotype in chronic kidney disease
- (2020) Denise Mafra et al. Nature Reviews Nephrology
- WNT–β-catenin signalling — a versatile player in kidney injury and repair
- (2020) Stefan J. Schunk et al. Nature Reviews Nephrology
- Colchicine in Patients with Chronic Coronary Disease
- (2020) Stefan M. Nidorf et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes
- (2020) George L. Bakris et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure
- (2020) Wesley Tyler Abplanalp et al. CIRCULATION RESEARCH
- Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A- and TET2-driver gene mutations
- (2020) Birgit Assmus et al. EUROPEAN HEART JOURNAL
- Lipoproteins in chronic kidney disease: from bench to bedside
- (2020) Thimoteus Speer et al. EUROPEAN HEART JOURNAL
- Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
- (2020) Pablo E. Pergola et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Sleep modulates haematopoiesis and protects against atherosclerosis
- (2019) Cameron S. McAlpine et al. NATURE
- The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin
- (2019) Laura C. Burzynski et al. IMMUNITY
- IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD
- (2019) Adriana M. Hung et al. Clinical Journal of the American Society of Nephrology
- Canagliflozin reduces inflammation and fibrosis biomarkers: a potential mechanism of action for beneficial effects of SGLT2 inhibitors in diabetic kidney disease
- (2019) Hiddo J. L. Heerspink et al. DIABETOLOGIA
- Cellular Senescence in the Kidney
- (2019) Marie-Helena Docherty et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Effect of bardoxolone methyl on the urine albumin-to-creatinine ratio in patients with type 2 diabetes and stage 4 chronic kidney disease.
- (2019) Peter Rossing et al. KIDNEY INTERNATIONAL
- Intestinal microbiome and fitness in kidney disease
- (2019) Björn Meijers et al. Nature Reviews Nephrology
- Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
- (2019) Natalia Robledinos-Antón et al. Oxidative Medicine and Cellular Longevity
- Residual inflammatory risk associated with interleukin-18 and interleukin-6 after successful interleukin-1β inhibition with canakinumab: further rationale for the development of targeted anti-cytokine therapies for the treatment of atherothrombosis
- (2019) Paul M Ridker et al. EUROPEAN HEART JOURNAL
- Clonal haematopoiesis in patients with degenerative aortic valve stenosis undergoing transcatheter aortic valve implantation
- (2019) Silvia Mas-Peiro et al. EUROPEAN HEART JOURNAL
- Anemia of Inflammation
- (2019) Tomas Ganz NEW ENGLAND JOURNAL OF MEDICINE
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
- (2019) LaTonya J. Hickson et al. EBioMedicine
- Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells
- (2019) Vanessa Frodermann et al. NATURE MEDICINE
- Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction
- (2019) Jean-Claude Tardif et al. NEW ENGLAND JOURNAL OF MEDICINE
- Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
- (2019) Stephen Zewinger et al. NATURE IMMUNOLOGY
- Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights
- (2018) Tadayoshi Karasawa et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Immune Training Unlocks Innate Potential
- (2018) Wilbur M. Song et al. CELL
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
- (2018) Anette Christ et al. CELL
- Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
- (2018) Ioannis Mitroulis et al. CELL
- BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis
- (2018) Eva Kaufmann et al. CELL
- BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity
- (2018) Rob J.W. Arts et al. Cell Host & Microbe
- Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1
- (2018) Daniel J. Drucker Cell Metabolism
- Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis and Atherogenesis
- (2018) Marit Westerterp et al. CIRCULATION
- Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability
- (2018) Nicole Paulin et al. CIRCULATION
- Microbiome and Cardiovascular Disease in CKD
- (2018) Anna Jovanovich et al. Clinical Journal of the American Society of Nephrology
- OUP accepted manuscript
- (2018) EUROPEAN HEART JOURNAL
- Niches for Hematopoietic Stem Cells and Their Progeny
- (2018) Qiaozhi Wei et al. IMMUNITY
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
- Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
- (2018) Dave Boucher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome
- (2018) Soichi Sano et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Inhibition of Interleukin-1β by Canakinumab and Cardiovascular Outcomes in Patients With Chronic Kidney Disease
- (2018) Paul M Ridker et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Interleukin-1βActivates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis
- (2018) Dario R. Lemos et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD
- (2018) Takanori Komada et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial
- (2018) Paul M Ridker et al. LANCET
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts
- (2018) Ramón Estruch et al. NEW ENGLAND JOURNAL OF MEDICINE
- Relationship of Interleukin-1β Blockade With Incident Gout and Serum Uric Acid Levels
- (2018) Daniel H. Solomon et al. ANNALS OF INTERNAL MEDICINE
- Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion
- (2018) Mercedes Monteleone et al. Cell Reports
- Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy
- (2018) Tianxi Cai et al. JAMA Cardiology
- Haematopoiesis in the era of advanced single-cell technologies
- (2018) Sten Eirik W. Jacobsen et al. NATURE CELL BIOLOGY
- Low-Dose Methotrexate for the Prevention of Atherosclerotic Events
- (2018) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure
- (2018) Lena Dorsheimer et al. JAMA Cardiology
- Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease
- (2017) Stephen Zewinger et al. EUROPEAN HEART JOURNAL
- Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease
- (2017) Jair Munoz Mendoza et al. KIDNEY INTERNATIONAL
- Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial
- (2017) Paul M Ridker et al. LANCET
- Human haematopoietic stem cell lineage commitment is a continuous process
- (2017) Lars Velten et al. NATURE CELL BIOLOGY
- JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
- (2017) Daniella M. Schwartz et al. NATURE REVIEWS DRUG DISCOVERY
- Crystal nephropathies: mechanisms of crystal-induced kidney injury
- (2017) Shrikant R. Mulay et al. Nature Reviews Nephrology
- Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
- (2017) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
- (2017) José J. Fuster et al. SCIENCE
- Biomarkers of Cardiovascular Disease and Mortality Risk in Patients with Advanced CKD
- (2016) J. Sun et al. Clinical Journal of the American Society of Nephrology
- Inflammation and Progression of CKD: The CRIC Study
- (2016) R. L. Amdur et al. Clinical Journal of the American Society of Nephrology
- Residual inflammatory risk: addressing the obverse side of the atherosclerosis prevention coin
- (2016) Paul M Ridker EUROPEAN HEART JOURNAL
- Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial
- (2016) Ola Kleveland et al. EUROPEAN HEART JOURNAL
- Human Monocytes Engage an Alternative Inflammasome Pathway
- (2016) Moritz M. Gaidt et al. IMMUNITY
- Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury
- (2016) Irina A. Leaf et al. JOURNAL OF CLINICAL INVESTIGATION
- Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy
- (2016) K. Shahzad et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- IL-1 Inhibition and Vascular Function in CKD
- (2016) Kristen L. Nowak et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Of Inflammasomes and Alarmins: IL-1 and IL-1 in Kidney Disease
- (2016) H.-J. Anders JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Interleukin 1α and the inflammatory process
- (2016) Nelson C Di Paolo et al. NATURE IMMUNOLOGY
- Crystallopathies
- (2016) Shrikant R. Mulay et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
- (2016) Eri H. Kobayashi et al. Nature Communications
- Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy
- (2016) Khurrum Shahzad et al. Scientific Reports
- Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
- (2015) D. P. Steensma et al. BLOOD
- Myocardial Infarction Activates CCR2+ Hematopoietic Stem and Progenitor Cells
- (2015) Partha Dutta et al. Cell Stem Cell
- Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction
- (2015) Hendrik B. Sager et al. CIRCULATION
- Achievement of Dual Low-Density Lipoprotein Cholesterol and High-Sensitivity C-Reactive Protein Targets More Frequent With the Addition of Ezetimibe to Simvastatin and Associated With Better Outcomes in IMPROVE-ITCLINICAL PERSPECTIVES
- (2015) Erin A. Bohula et al. CIRCULATION
- Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation
- (2015) Dan Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans
- (2015) Nike Müller et al. JOURNAL OF LIPID RESEARCH
- Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy
- (2015) A. Shah et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy
- (2015) Khurrum Shahzad et al. KIDNEY INTERNATIONAL
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- (2015) Bennett G Childs et al. NATURE MEDICINE
- Innate immunity in CKD-associated vascular diseases
- (2015) Stephen Zewinger et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis
- (2015) A. Warnatsch et al. SCIENCE
- ASC in Renal Collecting Duct Epithelial Cells Contributes to Inflammation and Injury after Unilateral Ureteral Obstruction
- (2014) Takanori Komada et al. AMERICAN JOURNAL OF PATHOLOGY
- Carbamylated low-density lipoprotein induces endothelial dysfunction
- (2014) Thimoteus Speer et al. EUROPEAN HEART JOURNAL
- Nod-like Receptor Protein 3 (NLRP3) Inflammasome Activation and Podocyte Injury via Thioredoxin-Interacting Protein (TXNIP) during Hyperhomocysteinemia
- (2014) Justine M. Abais et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
- (2014) P. Gurung et al. JOURNAL OF IMMUNOLOGY
- HDL Cholesterol Is Not Associated with Lower Mortality in Patients with Kidney Dysfunction
- (2014) S. Zewinger et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD
- (2014) G. Schulman et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Inflammatory caspases are innate immune receptors for intracellular LPS
- (2014) Jianjin Shi et al. NATURE
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Chronic variable stress activates hematopoietic stem cells
- (2014) Timo Heidt et al. NATURE MEDICINE
- Age-related mutations associated with clonal hematopoietic expansion and malignancies
- (2014) Mingchao Xie et al. NATURE MEDICINE
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
- (2014) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis
- (2013) Prabhakara R. Nagareddy et al. Cell Metabolism
- Abnormal High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2
- (2013) Thimoteus Speer et al. IMMUNITY
- RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3
- (2013) John R. Lukens et al. NATURE
- Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis
- (2013) Stefan Freigang et al. NATURE IMMUNOLOGY
- Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
- (2013) Robert A Koeth et al. NATURE MEDICINE
- Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease
- (2013) Dick de Zeeuw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of dietary composition of weight loss diets on high-sensitivity c-reactive protein: The Randomized POUNDS LOST trial
- (2013) Jacinda M. Nicklas et al. Obesity
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli During Hyperhomocysteinemia
- (2012) Justine M. Abais et al. ANTIOXIDANTS & REDOX SIGNALING
- Inflammasome-Independent NLRP3 Augments TGF- Signaling in Kidney Epithelium
- (2012) W. Wang et al. JOURNAL OF IMMUNOLOGY
- Cellular Senescence Limits Regenerative Capacity and Allograft Survival
- (2012) H. Braun et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
- (2012) LANCET
- A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death
- (2012) Laura S. Dickens et al. MOLECULAR CELL
- Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels
- (2011) Abbas Dehghan et al. CIRCULATION
- IL-1 Receptor Antagonist Reduces Inflammation in Hemodialysis Patients
- (2011) A. M. Hung et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Markers of inflammation predict the long-term risk of developing chronic kidney disease: a population-based cohort study
- (2011) Anoop Shankar et al. KIDNEY INTERNATIONAL
- Interleukin-1 accounts for intrarenal Th17 cell activation during ureteral obstruction
- (2011) Jana Pindjakova et al. KIDNEY INTERNATIONAL
- Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α
- (2011) Inna S. Afonina et al. MOLECULAR CELL
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
- (2011) Zeneng Wang et al. NATURE
- Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes
- (2011) Pablo E. Pergola et al. NEW ENGLAND JOURNAL OF MEDICINE
- Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment
- (2011) F. Notta et al. SCIENCE
- The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD
- (2010) A. Vilaysane et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Inflammatory networks during cellular senescence: causes and consequences
- (2010) Adam Freund et al. TRENDS IN MOLECULAR MEDICINE
- Immunological and Inflammatory Functions of the Interleukin-1 Family
- (2009) Charles A. Dinarello Annual Review of Immunology
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
- (2008) Juan C. Acosta et al. CELL
- Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
- (2008) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started