Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure

The evolutionary dynamics and fitness landscape of clonal hematopoiesis

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Multifaceted deregulation of gene expression and protein synthesis with age

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Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging

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Inflammatory cytokines promote clonal hematopoiesis with specific mutations in ulcerative colitis patients

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Clonal hematopoiesis, aging, and cardiovascular diseases

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Lineage restriction analyses in CHIP indicate myeloid bias forTET2and multipotent stem cell origin forDNMT3A

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CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular DiseaseNovelty and Significance

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Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome

(2018) Soichi Sano et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The human heart contains distinct macrophage subsets with divergent origins and functions

(2018) Geetika Bajpai et al.   NATURE MEDICINE

Myeloid cell contributions to cardiovascular health and disease

(2018) Matthias Nahrendorf   NATURE MEDICINE

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

(2018) Joseph A. Fraietta et al.   NATURE

Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure

(2018) Lena Dorsheimer et al.   JAMA Cardiology

Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

(2017) Paul M Maciocia et al.   NATURE MEDICINE

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

(2017) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

(2017) José J. Fuster et al.   SCIENCE

Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer

(2017) Sara Santagata et al.   Oncotarget

Cell Competition and Its Role in the Regulation of Cell Fitness from Development to Cancer

(2016) Aida Di Gregorio et al.   DEVELOPMENTAL CELL

Control of T cell antigen reactivity via programmed TCR downregulation

(2016) Alena M Gallegos et al.   NATURE IMMUNOLOGY

Ribosomal Protein L13a Deficiency in Macrophages Promotes Atherosclerosis by Limiting Translation Control-Dependent Retardation of Inflammation

(2014) Abhijit Basu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

(2014) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcription factor interplay in T helper cell differentiation

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