Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury

A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides

(2020) Anna Wolska et al.   Science Translational Medicine

Lipoproteins in chronic kidney disease: from bench to bedside

(2020) Thimoteus Speer et al.   EUROPEAN HEART JOURNAL

Apolipoprotein C-III Strongly Correlates with Activated Factor VII–Anti-Thrombin Complex: An Additional Link between Plasma Lipids and Coagulation

(2019) Marcello Baroni et al.   THROMBOSIS AND HAEMOSTASIS

Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome

(2019) Joseph L. Witztum et al.   NEW ENGLAND JOURNAL OF MEDICINE

The YB-1:Notch-3 axis modulates immune cell responses and organ damage in systemic lupus erythematosus

(2019) Daniel M. Breitkopf et al.   KIDNEY INTERNATIONAL

Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

(2019) Stephen Zewinger et al.   NATURE IMMUNOLOGY

Non-targeted metabolomic biomarkers and metabotypes of type 2 diabetes: A cross-sectional study of PREDIMED trial participants

(2018) M. Urpi-Sarda et al.   DIABETES & METABOLISM

Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss

(2018) Stephen Zewinger et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease

(2018) Felix Kork et al.   NEUROLOGY

Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease

(2017) Stephen Zewinger et al.   EUROPEAN HEART JOURNAL

Clot Structure: A Potent Mortality Risk Factor in Patients on Hemodialysis

(2017) Katharina Schuett et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

(2017) Sumeet A Khetarpal et al.   NATURE MEDICINE

High-Density Lipoprotein Subspecies Defined by Presence of Apolipoprotein C-III and Incident Coronary Heart Disease in Four Cohorts

(2017) Majken K. Jensen et al.   CIRCULATION

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

(2016) Philip L.S.M. Gordts et al.   JOURNAL OF CLINICAL INVESTIGATION

Group-based multi-trajectory modeling

(2016) Daniel S Nagin et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Guanidinylations of albumin decreased binding capacity of hydrophobic metabolites

(2015) M. Rueth et al.   Acta Physiologica

Serum amyloid A: high-density lipoproteins interaction and cardiovascular risk

(2015) Stephen Zewinger et al.   EUROPEAN HEART JOURNAL

Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease

(2015) Prathibha R. Gajjala et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia

(2015) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes

(2015) Karin Åvall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carbamylated low-density lipoprotein induces endothelial dysfunction

(2014) Thimoteus Speer et al.   EUROPEAN HEART JOURNAL

HDL Cholesterol Is Not Associated with Lower Mortality in Patients with Kidney Dysfunction

(2014) S. Zewinger et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

HDL in Children with CKD Promotes Endothelial Dysfunction and an Abnormal Vascular Phenotype

(2014) R. Shroff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure

(2014) Alberto Ortiz et al.   LANCET

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

(2014) Anders Berg Jørgensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting APOC3 in the Familial Chylomicronemia Syndrome

(2014) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

(2013) Mark J. Graham et al.   CIRCULATION RESEARCH

Abnormal High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2

(2013) Thimoteus Speer et al.   IMMUNITY

Uraemic dyslipidaemia revisited: role of high-density lipoprotein

(2013) T. Speer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Statins suppress apolipoprotein CIII-induced vascular endothelial cell activation and monocyte adhesion

(2012) Chunyu Zheng et al.   EUROPEAN HEART JOURNAL

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

(2010)   LANCET

Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease

(2010) Kitt Falk Petersen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

(2008) T. I. Pollin et al.   SCIENCE