The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
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Title
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
Authors
Keywords
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Journal
NATURE
Volume 592, Issue 7853, Pages 296-301
Publisher
Springer Science and Business Media LLC
Online
2021-03-18
DOI
10.1038/s41586-021-03341-5
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- (2020) Alma Zernecke et al. CIRCULATION RESEARCH
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- (2017) Daniella M. Schwartz et al. NATURE REVIEWS DRUG DISCOVERY
- Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
- (2017) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
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- Arterial Effects of Canakinumab in Patients With Atherosclerosis and Type 2 Diabetes or Glucose Intolerance
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- Effects of Ruxolitinib Treatment on Metabolic and Nutritional Parameters in Patients With Myelofibrosis From COMFORT-I
- (2015) Ruben A. Mesa et al. Clinical Lymphoma Myeloma & Leukemia
- Inflammation and plaque vulnerability
- (2015) G. K. Hansson et al. JOURNAL OF INTERNAL MEDICINE
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- (2013) Clinton S Robbins et al. NATURE MEDICINE
- Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera
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- (2012) Johannes Schindelin et al. NATURE METHODS
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- (2010) Hugo J. Snippert et al. CELL
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- (2010) Peter Duewell et al. NATURE
- Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
- (2009) Steffen Durinck et al. Nature Protocols
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