Innate immunity in CKD-associated vascular diseases

Reducing Vascular Calcification by Anti-IL-1β Monoclonal Antibody in a Mouse Model of Familial Hypercholesterolemia

(2015) Zuhier Awan et al.   ANGIOLOGY

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

(2015) S M Krishnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Toll-like receptors: Activation, signalling and transcriptional modulation

(2015) Dominic De Nardo   CYTOKINE

Serum amyloid A: high-density lipoproteins interaction and cardiovascular risk

(2015) Stephen Zewinger et al.   EUROPEAN HEART JOURNAL

Recognition of Bacterial Signal Peptides by Mammalian Formyl Peptide Receptors

(2015) Bernd Bufe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beyond Tissue Injury--Damage-Associated Molecular Patterns, Toll-Like Receptors, and Inflammasomes Also Drive Regeneration and Fibrosis

(2014) H.-J. Anders et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure

(2014) Alberto Ortiz et al.   LANCET

Pattern recognition receptors and the inflammasome in kidney disease

(2014) Jaklien C. Leemans et al.   Nature Reviews Nephrology

Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in l-NAME-induced hypertension

(2013) Daniel Sollinger et al.   CARDIOVASCULAR RESEARCH

Sterol Regulatory Element Binding Protein 2 Activation of NLRP3 Inflammasome in Endothelium Mediates Hemodynamic-Induced Atherosclerosis Susceptibility

(2013) Han Xiao et al.   CIRCULATION

Abnormal High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2

(2013) Thimoteus Speer et al.   IMMUNITY

Nalp3 inflammasome is activated and required for vascular smooth muscle cell calcification

(2013) Chaoyang Wen et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

(2013) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

(2012) Paul M Ridker et al.   CIRCULATION

Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats

(2012) Gisele F. Bomfim et al.   CLINICAL SCIENCE

Mechanistic Insights into Vascular Calcification in CKD

(2012) R. Shroff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

(2011) Paul M Ridker et al.   AMERICAN HEART JOURNAL

BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium

(2011) T. Helbing et al.   BLOOD

The Regulation of Valvular and Vascular Sclerosis by Osteogenic Morphogens

(2011) Kristina I. Boström et al.   CIRCULATION RESEARCH

IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension

(2011) Kensuke Tsushima et al.   FASEB JOURNAL

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Oxidized Low Density Lipoprotein Induces Bone Morphogenetic Protein-2 in Coronary Artery Endothelial Cells via Toll-like Receptors 2 and 4

(2011) Xin Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

Chronic kidney disease

(2011) Andrew S Levey et al.   LANCET

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Leukocyte Toll-Like Receptor Expression in End-Stage Kidney Disease

(2010) P. Gollapudi et al.   AMERICAN JOURNAL OF NEPHROLOGY

Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration

(2010) K. Grote et al.   BLOOD

Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress

(2010) Tracie A. Seimon et al.   Cell Metabolism

Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

(2010) Xiaoxia Z. West et al.   NATURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Toll-like receptor expression in monocytes in patients with chronic kidney disease and haemodialysis: relation with inflammation

(2010) M. Koc et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Pro-Osteogenic Phenotype of Human Aortic Valve Interstitial Cells Is Associated With Higher Levels of Toll-Like Receptors 2 and 4 and Enhanced Expression of Bone Morphogenetic Protein 2

(2009) Xiaoping Yang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inhibition of Interleukin-1 by Anakinra Improves Vascular and Left Ventricular Function in Patients With Rheumatoid Arthritis

(2008) Ignatios Ikonomidis et al.   CIRCULATION

Inflammation and cardiovascular events in individuals with and without chronic kidney disease

(2008) D.E. Weiner et al.   KIDNEY INTERNATIONAL

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE