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Title
The Risks of miRNA Therapeutics: In a Drug Target Perspective
Authors
Keywords
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Journal
Drug Design Development and Therapy
Volume Volume 15, Issue -, Pages 721-733
Publisher
Informa UK Limited
Online
2021-02-22
DOI
10.2147/dddt.s288859
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Note: Only part of the references are listed.- Overexpression of tripartite motif containing 26 inhibits non‐small cell lung cancer cell growth by suppressing PI3K/AKT signaling
- (2020) Jia‐Li Tao et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- 2019 FDA drug approvals
- (2020) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- 2018 FDA drug approvals
- (2019) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- RNAi therapeutic and its innovative biotechnological evolution
- (2019) Yuhua Weng et al. BIOTECHNOLOGY ADVANCES
- MiR-122 Targets SerpinB3 and Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma
- (2019) Cristian Turato et al. Journal of Clinical Medicine
- KEGG Mapper for inferring cellular functions from protein sequences
- (2019) Minoru Kanehisa et al. PROTEIN SCIENCE
- miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database
- (2019) Hsi-Yuan Huang et al. NUCLEIC ACIDS RESEARCH
- Recognition Sites for Cancer-targeting Drug Delivery Systems
- (2019) Siyu Guan et al. CURRENT DRUG METABOLISM
- Magnesium-Stabilized Multifunctional DNA Nanoparticles for Tumor-Targeted and pH-Responsive Drug Delivery
- (2018) Haoran Zhao et al. ACS Applied Materials & Interfaces
- 2017 FDA drug approvals
- (2018) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial
- (2017) Meike H van der Ree et al. LANCET
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- 2016 FDA drug approvals
- (2017) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level
- (2017) Dong Wang et al. NUCLEIC ACIDS RESEARCH
- miR-204-5p acts as a tumor suppressor by targeting matrix metalloproteinases-9 and B-cell lymphoma-2 in malignant melanoma
- (2017) Wenkang Luan et al. OncoTargets and Therapy
- MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells
- (2017) Koichiro Minami et al. Oncotarget
- 3B, a novel photosensitizer, inhibits glycolysis and inflammation via miR-155-5p and breaks the JAK/STAT3/SOCS1 feedback loop in human breast cancer cells
- (2016) Kecheng Lei et al. BIOMEDICINE & PHARMACOTHERAPY
- Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
- (2016) Dong-liang Chen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- 2015 FDA drug approvals
- (2016) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- A comprehensive map of molecular drug targets
- (2016) Rita Santos et al. NATURE REVIEWS DRUG DISCOVERY
- E2F1-miR-20a-5p/20b-5p auto-regulatory feedback loop involved in myoblast proliferation and differentiation
- (2016) Wen Luo et al. Scientific Reports
- Low miR-145 silenced by DNA methylation promotes NSCLC cell proliferation, migration and invasion by targeting mucin 1
- (2015) Zhiqiang Ye et al. CANCER BIOLOGY & THERAPY
- miR-122 – A key factor and therapeutic target in liver disease
- (2015) Simonetta Bandiera et al. JOURNAL OF HEPATOLOGY
- Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis
- (2015) Zhou Xu et al. NEURO-ONCOLOGY
- MicroRNA let-7c Inhibits Cell Proliferation and Induces Cell Cycle Arrest by Targeting CDC25A in Human Hepatocellular Carcinoma
- (2015) Xiuming Zhu et al. PLoS One
- Knockdown of miR-221 promotes the cisplatin-inducing apoptosis by targeting the BIM-Bax/Bak axis in breast cancer
- (2015) Zhiqiang Ye et al. TUMOR BIOLOGY
- MicroRNA profiling identifies MiR-195 suppresses osteosarcoma cell metastasis by targeting CCND1
- (2015) Kang Han et al. Oncotarget
- Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer
- (2015) Zhu-lin Luo et al. Oncotarget
- MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer
- (2015) Gloria Bertoli et al. Theranostics
- miR-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2
- (2014) LI YING LIU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- MicroRNA miR-21 Attenuates Human Cytomegalovirus Replication in Neural Cells by Targeting Cdc25a
- (2014) Ya-Ru Fu et al. JOURNAL OF VIROLOGY
- Therapeutic targeting of microRNAs: current status and future challenges
- (2014) Zhonghan Li et al. NATURE REVIEWS DRUG DISCOVERY
- MicroRNA-195-5p is a potential diagnostic and therapeutic target for breast cancer
- (2014) QIFENG LUO et al. ONCOLOGY REPORTS
- MicroRNA-214 provokes cardiac hypertrophy via repression of EZH2
- (2013) Tao Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor
- (2013) Jing Zhang et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Progress in microRNA delivery
- (2013) Yu Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Natural RNA circles function as efficient microRNA sponges
- (2013) Thomas B. Hansen et al. NATURE
- Prognostic Implications of MicoRNA miR-195 Expression in Human Tongue Squamous Cell Carcinoma
- (2013) Ling-fei Jia et al. PLoS One
- miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1
- (2013) CHAOYANG SUN et al. Oncology Letters
- MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1
- (2012) Jing Liu et al. BMC CANCER
- MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome
- (2012) J Ryan et al. BRITISH JOURNAL OF CANCER
- Resistance to EGFR blockade in colorectal cancer: liquid biopsies and latent subclones
- (2012) David J Konieczkowski et al. CELL RESEARCH
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- (2012) Jun Zhang et al. FEBS LETTERS
- Oral delivery of small RNA and DNA
- (2012) Diane C. Forbes et al. JOURNAL OF CONTROLLED RELEASE
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- KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases
- (2011) Chen Xie et al. NUCLEIC ACIDS RESEARCH
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- (2010) Elisa Vilardo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Xing J Zhang et al. Journal of Hematology & Oncology
- Let-7g targets collagen type I α2 and inhibits cell migration in hepatocellular carcinoma
- (2010) Junfang Ji et al. JOURNAL OF HEPATOLOGY
- MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1
- (2010) W. Pan et al. JOURNAL OF IMMUNOLOGY
- MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor
- (2010) Jun Tie et al. PLoS Genetics
- MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
- (2009) R. Garzon et al. BLOOD
- microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells
- (2009) P. Wang et al. CANCER RESEARCH
- MicroRNA-661, a c/EBP Target, Inhibits Metastatic Tumor Antigen 1 and Regulates Its Functions
- (2009) S. D. N. Reddy et al. CANCER RESEARCH
- MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality
- (2009) L. Gramantieri et al. CLINICAL CANCER RESEARCH
- MicroRNA-21 Regulates the Proliferation and Invasion in Esophageal Squamous Cell Carcinoma
- (2009) Y. Hiyoshi et al. CLINICAL CANCER RESEARCH
- MicroRNA-141 Regulates Smad Interacting Protein 1 (SIP1) and Inhibits Migration and Invasion of Colorectal Cancer Cells
- (2009) Minghua Hu et al. DIGESTIVE DISEASES AND SCIENCES
- Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
- (2009) Junfang Ji et al. HEPATOLOGY
- MicroRNA-122 Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells and Sensitizes These Cells to Sorafenib
- (2009) Shoumei Bai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of an NF-κB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells
- (2009) Aileen I. Pogue et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
- (2009) D. R. Cochrane et al. MOLECULAR CANCER THERAPEUTICS
- Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
- (2009) Aly A Khan et al. NATURE BIOTECHNOLOGY
- Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation
- (2008) D. Sampath et al. BLOOD
- MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma
- (2008) Shuai Li et al. HEPATOLOGY
- Down-regulation of Micro-RNA-1 (miR-1) in Lung Cancer
- (2008) Mohd W. Nasser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miR-122, a paradigm for the role of microRNAs in the liver
- (2008) Muriel Girard et al. JOURNAL OF HEPATOLOGY
- A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis
- (2008) Catherine Labbaye et al. NATURE CELL BIOLOGY
- Nanoparticle therapeutics: an emerging treatment modality for cancer
- (2008) Mark E. Davis et al. NATURE REVIEWS DRUG DISCOVERY
- MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
- (2008) F Fornari et al. ONCOGENE
- Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer
- (2008) S. Varambally et al. SCIENCE
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