Astrocyte-enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia

microRNAs: Innovative Targets for Cerebral Ischemia and Stroke

(2013) Yi-Bing Ouyang et al.   CURRENT DRUG TARGETS

MicroRNA miR-29c Down-Regulation Leading to De-Repression of Its Target DNA Methyltransferase 3a Promotes Ischemic Brain Damage

(2013) Gopal Pandi et al.   PLoS One

miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis

(2011) A. J. Kole et al.   GENES & DEVELOPMENT

miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes

(2011) Yi-Bing Ouyang et al.   MITOCHONDRION

miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo

(2011) Yi-Bing Ouyang et al.   NEUROBIOLOGY OF DISEASE

Upregulated miR-29b promotes neuronal cell death by inhibiting Bcl2L2 after ischemic brain injury

(2011) Guodong Shi et al.   EXPERIMENTAL BRAIN RESEARCH

Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo

(2010) Takuro Tsuchiya et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia

(2010) Lijun Xu et al.   GLIA

MicroRNA expression changes in the hippocampi of rats subjected to global ischemia

(2010) Yuan Yuan et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability

(2010) Helena P. Bonner et al.   JOURNAL OF NEUROCHEMISTRY

Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress

(2010) Yi-Bing Ouyang et al.   MITOCHONDRION

Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3

(2010) M. Shioya et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

(2010) M Fricker et al.   Cell Death & Disease

Transient Focal Ischemia Induces Extensive Temporal Changes in Rat Cerebral MicroRNAome

(2009) Ashuthosh Dharap et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain and Blood microRNA Expression Profiling of Ischemic Stroke, Intracerebral Hemorrhage, and Kainate Seizures

(2009) Da-Zhi Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion

(2008) Kandiah Jeyaseelan et al.   STROKE

Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia

(2008) Kuniyasu Niizuma et al.   STROKE