Ketogenic diets and protective mechanisms in epilepsy, metabolic disorders, cancer, neuronal loss, and muscle and nerve degeneration

Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer’s Disease and Parkinson’s Disease)

(2019) Dariusz Włodarek   Nutrients

Ketogenic diet in cancer therapy

(2018) Daniela D. Weber et al.   Aging-US

A ketogenic amino acid rich diet benefits mitochondrial homeostasis by altering the AKT/4EBP1 and autophagy signaling pathways in the gastrocnemius and soleus

(2018) Jinpeng Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Decreased ghrelin and des-acyl ghrelin plasma levels in patients affected by pharmacoresistant epilepsy and maintained on the ketogenic diet

(2018) Maddalena Marchiò et al.   CLINICAL NUTRITION

Overweight and diabetes prevention: is a low-carbohydrate–high-fat diet recommendable?

(2018) Fred Brouns   EUROPEAN JOURNAL OF NUTRITION

The ketogenic diet in disease and development

(2018) Denis Barry et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Structural and Functional Rescue of Chronic Metabolically Stressed Optic Nerves through Respiration

(2018) Mohammad Harun-Or-Rashid et al.   JOURNAL OF NEUROSCIENCE

Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial

(2018) Salvador Vargas et al.   Journal of the International Society of Sports Nutrition

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

(2018) Katrin Augustin et al.   LANCET NEUROLOGY

A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis

(2018) Md Mahdi Hasan-Olive et al.   NEUROCHEMICAL RESEARCH

Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements

(2018) Milan Holeček   Nutrition & Metabolism

Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease.

(2018) Ilona Joniec-Maciejak et al.   Pharmacological Reports

A Ketogenic Formula Prevents Tumor Progression and Cancer Cachexia by Attenuating Systemic Inflammation in Colon 26 Tumor-Bearing Mice

(2018) et al.   Nutrients

An 8-Week Ketogenic Low Carbohydrate, High Fat Diet Enhanced Exhaustive Exercise Capacity in Mice

(2018) Sihui Ma et al.   Nutrients

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice

(2018) David Ma et al.   Scientific Reports

Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study

(2018) Sarah J. Hallberg et al.   Diabetes Therapy

Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study

(2018) Sarah J. Hallberg et al.   Diabetes Therapy

Association between insulin resistance and the development of cardiovascular disease

(2018) Valeska Ormazabal et al.   Cardiovascular Diabetology

Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet

(2018) Michael A. Cooper et al.   EXPERIMENTAL PHYSIOLOGY

An 8-Week, Low Carbohydrate, High Fat, Ketogenic Diet Enhanced Exhaustive Exercise Capacity in Mice Part 2: Effect on Fatigue Recovery, Post-Exercise Biomarkers and Anti-Oxidation Capacity

(2018) Qingyi Huang et al.   Nutrients

Single Dose Administration of Taheebo Polyphenol Enhances Endurance Capacity in Mice

(2018) Koichi Yada et al.   Scientific Reports

An 8-Week Ketogenic Diet Alternated Interleukin-6, Ketolytic and Lipolytic Gene Expression, and Enhanced Exercise Capacity in Mice

(2018) Sihui Ma et al.   Nutrients

Beneficial effects of ketogenic diets for cancer patients: a realist review with focus on evidence and confirmation

(2017) Rainer J. Klement   MEDICAL ONCOLOGY

Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies

(2017) Christophe Kosinski et al.   Nutrients

Ketogenic diets: from cancer to mitochondrial diseases and beyond

(2016) Ana F. Branco et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice

(2016) Kristoffer Svensson et al.   FASEB JOURNAL

PNPLA3 gene in liver diseases

(2016) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

Use of dietary therapies amongst patients with GLUT1 deficiency syndrome

(2016) Hannah R. Kass et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Alternate-Day High-Fat Diet Induces an Increase in Mitochondrial Enzyme Activities and Protein Content in Rat Skeletal Muscle

(2016) Xi Li et al.   Nutrients

Benefits of use, and tolerance of, medium-chain triglyceride medical food in the management of Japanese patients with Alzheimer’s disease: a prospective, open-label pilot study

(2016) Tohru Ohnuma et al.   Clinical Interventions in Aging

Growth of Human Colon Cancer Cells in Nude Mice is Delayed by Ketogenic Diet With or Without Omega-3 Fatty Acids and Medium-chain Triglycerides

(2015) Guang-Wei Hao et al.   Asian Pacific Journal of Cancer Prevention

Ketogenic diets in patients with inherited metabolic disorders

(2015) S. Scholl-Bürgi et al.   JOURNAL OF INHERITED METABOLIC DISEASE

The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis

(2015) Chiara Saponaro et al.   Nutrients

Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model

(2015) Raphael Johannes Morscher et al.   PLoS One

Chronic Dietary Administration of the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG) Inhibits the Growth of Implanted Ehrlich’s Ascites Tumor in Mice

(2015) Saurabh Singh et al.   PLoS One

PNPLA3gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease

(2014) Jiayun Shen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Ketogenic diets, mitochondria, and neurological diseases

(2014) Lindsey B. Gano et al.   JOURNAL OF LIPID RESEARCH

Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain

(2014) Yifan Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Glycogen storage disease type III: modified Atkins diet improves myopathy

(2014) Sebene Mayorandan et al.   Orphanet Journal of Rare Diseases

Ketogenic Diet for Obesity: Friend or Foe?

(2014) Antonio Paoli   International Journal of Environmental Research and Public Health

Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma

(2014) Christine M. Dengler-Crish et al.   Frontiers in Neuroscience

Neuroactive Peptides as Putative Mediators of Antiepileptic Ketogenic Diets

(2014) Carmela Giordano et al.   Frontiers in Neurology

Deep sequencing reveals increased DNA methylation in chronic rat epilepsy

(2013) Katja Kobow et al.   ACTA NEUROPATHOLOGICA

A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's Disease

(2013) Tina L. Beckett et al.   BRAIN RESEARCH

Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials

(2013) Nassib Bezerra Bueno et al.   BRITISH JOURNAL OF NUTRITION

Diets and nonalcoholic fatty liver disease: The good and the bad

(2013) Mohamed Asrih et al.   CLINICAL NUTRITION

A Focused Review of the Role of Ketone Bodies in Health and Disease

(2013) Muhammad Akram   JOURNAL OF MEDICINAL FOOD

Ketogenic diets

(2012) Eric H. Kossoff et al.   CURRENT OPINION IN NEUROLOGY

Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia

(2012) Raffaella Cusmai et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: Estimated potential contribution to brain energy metabolism

(2012) Alexandre Courchesne-Loyer et al.   NUTRITION

The ketogenic diet: metabolic influences on brain excitability and epilepsy

(2012) Andrew Lutas et al.   TRENDS IN NEUROSCIENCES

A very low carbohydrate ketogenic diet prevents the progression of hepatic steatosis caused by hyperglycemia in a juvenile obese mouse model

(2012) T Okuda et al.   Nutrition & Diabetes

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders

(2012) Carl E. Stafstrom et al.   Frontiers in Pharmacology

A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

(2011) Susan A. Masino et al.   JOURNAL OF CLINICAL INVESTIGATION

Single KATP Channel Opening in Response to Action Potential Firing in Mouse Dentate Granule Neurons

(2011) G. R. Tanner et al.   JOURNAL OF NEUROSCIENCE

Carbohydrate restricted diet in conjunction with metformin and liraglutide is an effective treatment in patients with deteriorated type 2 diabetes mellitus: Proof-of-concept study

(2011) Jürgen E Müller et al.   Nutrition & Metabolism

Successful Treatment of Severe Cardiomyopathy in Glycogen Storage Disease Type III With D,L-3-Hydroxybutyrate, Ketogenic and High-Protein Diet

(2011) Vassili Valayannopoulos et al.   PEDIATRIC RESEARCH

The Role of Skeletal Muscle Glycogen Breakdown for Regulation of Insulin Sensitivity by Exercise

(2011) Jørgen Jensen et al.   Frontiers in Physiology

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

Insulin Sensitivity and Glucose Tolerance Are Altered by Maintenance on a Ketogenic Diet

(2010) Kimberly P. Kinzig et al.   ENDOCRINOLOGY

Ketogenic diet slows down mitochondrial myopathy progression in mice

(2010) Sofia Ahola-Erkkilä et al.   HUMAN MOLECULAR GENETICS

Metabolic Control of Vesicular Glutamate Transport and Release

(2010) Narinobu Juge et al.   NEURON

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

(2010) H. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of a ketogenic diet on ATP concentrations and the number of hippocampal mitochondria in Aldh5a1−/− mice

(2009) Kirk Nylen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

How Do We Define Cure of Diabetes?

(2009) J. B. Buse et al.   DIABETES CARE

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

(2009) Samuel T Henderson et al.   Nutrition & Metabolism

Mechanisms of Cancer Cachexia

(2009) Michael J. Tisdale   PHYSIOLOGICAL REVIEWS

Reduced Pain and Inflammation in Juvenile and Adult Rats Fed a Ketogenic Diet

(2009) David N. Ruskin et al.   PLoS One

Optimal clinical management of children receiving the ketogenic diet: Recommendations of the International Ketogenic Diet Study Group

(2008) Eric H. Kossoff et al.   EPILEPSIA

The ketogenic diet increases mitochondrial glutathione levels

(2008) Stuart G. Jarrett et al.   JOURNAL OF NEUROCHEMISTRY

Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

(2008) Jeff S. Volek et al.   LIPIDS

PGC-1α increases skeletal muscle lactate uptake by increasing the expression of MCT1 but not MCT2 or MCT4

(2008) Carley R. Benton et al.   PHYSIOLOGICAL GENOMICS