Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases
Authors
Keywords
-
Journal
AGEING RESEARCH REVIEWS
Volume 80, Issue -, Pages 101667
Publisher
Elsevier BV
Online
2022-06-15
DOI
10.1016/j.arr.2022.101667
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Molecular mechanisms and physiological functions of mitophagy
- (2021) Mashun Onishi et al. EMBO JOURNAL
- Epigenetic plasticity and redox regulation of neural stem cell state and fate
- (2021) Emmy Xue Yun Tay et al. FREE RADICAL BIOLOGY AND MEDICINE
- Function and regulation of the divisome for mitochondrial fission
- (2021) Felix Kraus et al. NATURE
- Mitochondrial and Autophagic Regulation of Adult Neurogenesis in the Healthy and Diseased Brain
- (2021) Hansruedi Büeler INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus
- (2021) Shawn F. Sorrells et al. JOURNAL OF NEUROSCIENCE
- Regulatory roles of mitochondria and metabolism in neurogenesis
- (2021) Ryohei Iwata et al. CURRENT OPINION IN NEUROBIOLOGY
- The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration
- (2021) Shofiul Azam et al. Frontiers in Cell and Developmental Biology
- Adult Neurogenesis: A Story Ranging from Controversial New Neurogenic Areas and Human Adult Neurogenesis to Molecular Regulation
- (2021) Perla Leal-Galicia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial dynamics and its impact on human health and diseases: inside the DRP1 blackbox
- (2021) Riddhi Banerjee et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Directly Reprogrammed Human Neurons to Understand Age-Related Energy Metabolism Impairment and Mitochondrial Dysfunction in Healthy Aging and Neurodegeneration
- (2021) Camila Gudenschwager et al. Oxidative Medicine and Cellular Longevity
- Combination therapy with astaxanthin and epidermal neural crest stem cells improves motor impairments and activates mitochondrial biogenesis in a rat model of spinal cord injury
- (2020) Leila Mohaghegh Shalmani et al. MITOCHONDRION
- Unraveling human adult hippocampal neurogenesis
- (2020) Miguel Flor-García et al. Nature Protocols
- The cell biology of mitochondrial membrane dynamics
- (2020) Marta Giacomello et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The effect of Matrigel as scaffold material for neural stem cell transplantation for treating spinal cord injury
- (2020) Jiuling Wang et al. Scientific Reports
- Functional effects of muscle PGC-1alpha in aged animals
- (2020) Steven Yang et al. Skeletal Muscle
- Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model
- (2020) Elisabete Ferreiro et al. NEUROBIOLOGY OF AGING
- The Molecular Determinants of Mitochondrial Membrane Contact With ER, Lysosomes and Peroxisomes in Neuronal Physiology and Pathology
- (2020) Yajin Liao et al. Frontiers in Cellular Neuroscience
- Stem Cells of the Aging Brain
- (2020) Alexandra M. Nicaise et al. Frontiers in Aging Neuroscience
- Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity
- (2020) Lisa M. Julian et al. Frontiers in Cell and Developmental Biology
- Neurogenesis From Embryo to Adult – Lessons From Flies and Mice
- (2020) Helena Mira et al. Frontiers in Cell and Developmental Biology
- Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
- (2020) Safak Caglayan et al. iScience
- Metabolic Enhancement of Glycolysis and Mitochondrial Respiration Are Essential for Neuronal Differentiation
- (2020) Ding Li et al. Cellular Reprogramming
- Cognitive Training as a Potential Activator of Hippocampal Neurogenesis in the Rat Model of Sporadic Alzheimer’s Disease
- (2020) Alena O. Burnyasheva et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial Fusion: The Machineries In and Out
- (2020) Song Gao et al. TRENDS IN CELL BIOLOGY
- Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting
- (2020) Carla Lopes et al. Frontiers in Cell and Developmental Biology
- Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases
- (2020) Marco Luciani et al. Frontiers in Molecular Biosciences
- Cell Proliferation in the Adult Chicken Hippocampus Correlates With Individual Differences in Time Spent in Outdoor Areas and Tonic Immobility
- (2020) Elena A. Armstrong et al. Frontiers in Veterinary Science
- Mitochondrial Superoxide Dismutase Specifies Early Neural Commitment by Modulating Mitochondrial Dynamics
- (2020) Smitha Bhaskar et al. iScience
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
- (2019) Elena P. Moreno-Jiménez et al. NATURE MEDICINE
- The A30P α-synuclein mutation decreases subventricular zone proliferation
- (2019) Xue-Ming Zhang et al. HUMAN MOLECULAR GENETICS
- Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons
- (2019) Federico Zambon et al. HUMAN MOLECULAR GENETICS
- Ultrastructure and dynamics of the actin−myosin II cytoskeleton during mitochondrial fission
- (2019) Changsong Yang et al. NATURE CELL BIOLOGY
- An analogue derived from phenylpropanoids ameliorates Alzheimer’s disease-like pathology and protects mitochondrial function
- (2019) Shichao Huang et al. NEUROBIOLOGY OF AGING
- Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality
- (2019) Jonas Walter et al. Stem Cell Reports
- Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways
- (2019) Artem P. Gureev et al. Frontiers in Genetics
- Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease
- (2019) P. Hemachandra Reddy et al. Cells
- Quality Control in Neurons: Mitophagy and Other Selective Autophagy Mechanisms
- (2019) Chantell S. Evans et al. JOURNAL OF MOLECULAR BIOLOGY
- Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer’s Disease iPSC-Derived Neural Stem Cells
- (2019) Patricia Martín-Maestro et al. MOLECULAR NEUROBIOLOGY
- Modifiable Risk Factors for Alzheimer’s Disease
- (2019) George A. Edwards III et al. Frontiers in Aging Neuroscience
- Current progress of mitochondrial transplantation that promotes neuronal regeneration
- (2019) Chu-Yuan Chang et al. Translational Neurodegeneration
- O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells
- (2019) Hyun Jik Lee et al. Cell Death & Disease
- Amyloid-β Oligomers-induced Mitochondrial DNA Repair Impairment Contributes to Altered Human Neural Stem Cell Differentiation
- (2019) Jing Lu et al. Current Alzheimer Research
- Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE -/- Mice
- (2019) Zarko Barjaktarovic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pleiotropic Mitochondria: The Influence of Mitochondria on Neuronal Development and Disease
- (2019) Vidhya Rangaraju et al. JOURNAL OF NEUROSCIENCE
- Transplantation of NSCs Promotes the Recovery of Cognitive Functions by Regulating Neurotransmitters in Rats with Traumatic Brain Injury
- (2019) Mei-ling Luo et al. NEUROCHEMICAL RESEARCH
- Mitochondria–Lysosome Crosstalk: From Physiology to Neurodegeneration
- (2019) Cláudia M. Deus et al. TRENDS IN MOLECULAR MEDICINE
- Enhanced lysosomal degradation maintains the quiescent state of neural stem cells
- (2019) Taeko Kobayashi et al. Nature Communications
- Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson’s models
- (2018) Atossa Shaltouki et al. ACTA NEUROPATHOLOGICA
- Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment
- (2018) Jimena H. Martínez et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease
- (2018) Ana C. Silva et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms
- (2018) Inhae Kang et al. FEBS LETTERS
- Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism
- (2018) Gary Yellen JOURNAL OF CELL BIOLOGY
- Lysosomes Support the Degradation, Signaling, and Mitochondrial Metabolism Necessary for Human Epidermal Differentiation
- (2018) Christine L. Monteleon et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Polyglutamine expansion diseases: More than simple repeats
- (2018) Alexandra Silva et al. JOURNAL OF STRUCTURAL BIOLOGY
- Accumulation of Mitochondrial DNA Common Deletion Since The Preataxic Stage of Machado-Joseph Disease
- (2018) Mafalda Raposo et al. MOLECULAR NEUROBIOLOGY
- Repeated Mesenchymal Stromal Cells Treatment Sustainably Alleviates Machado-Joseph Disease
- (2018) Catarina Oliveira Miranda et al. MOLECULAR THERAPY
- Neuroprotective Effects of Creatine in the CMVMJD135 Mouse Model of Spinocerebellar Ataxia Type 3
- (2018) Sara Duarte-Silva et al. MOVEMENT DISORDERS
- Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis
- (2018) Yvette C. Wong et al. NATURE
- Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults
- (2018) Shawn F. Sorrells et al. NATURE
- Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus
- (2018) Kirsten Thomsen et al. NEUROBIOLOGY OF AGING
- Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function
- (2018) Line V. Kristensen et al. NEUROCHEMISTRY INTERNATIONAL
- Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes
- (2018) P. Conforti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging
- (2018) Dena S. Leeman et al. SCIENCE
- Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients
- (2018) Julian H. Birnbaum et al. Stem Cell Research
- Generation of an induced pluripotent stem cell line from a patient with spinocerebellar ataxia type 3 (SCA3): HIHCNi002-A
- (2018) Stefanie Nicole Hayer et al. Stem Cell Research
- CRISPR/Cas9-Targeted Deletion of Polyglutamine in Spinocerebellar Ataxia Type 3-Derived Induced Pluripotent Stem Cells
- (2018) Shuming Ouyang et al. STEM CELLS AND DEVELOPMENT
- Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein
- (2018) Tammy Ryan et al. Nature Communications
- A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA
- (2018) Daniel Little et al. Scientific Reports
- The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease
- (2018) David C. Schöndorf et al. Cell Reports
- Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models
- (2018) Angelo Iannielli et al. Cell Reports
- Impaired Hippocampal Neurogenesis and its Enhancement with Ghrelin in 5XFAD Mice
- (2018) Minho Moon et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid β Peptide Compromises Neural Stem Cell Fate by Irreversibly Disturbing Mitochondrial Oxidative State and Blocking Mitochondrial Biogenesis and Dynamics
- (2018) Maria Filipe Ribeiro et al. MOLECULAR NEUROBIOLOGY
- Regulation of neural stem cell fate decisions by mitochondrial dynamics
- (2018) Arezu Jahani-Asl et al. Neural Regeneration Research
- Mitochondria in Developmental and Adult Neurogenesis
- (2018) Macarena S. Arrázola et al. NEUROTOXICITY RESEARCH
- Mitochondria as central regulators of neural stem cell fate and cognitive function
- (2018) Mireille Khacho et al. NATURE REVIEWS NEUROSCIENCE
- Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury
- (2018) Hyo Jeong Kim et al. Cell Death & Disease
- MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
- (2018) Amir Bahat et al. Nature Communications
- Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3
- (2018) Tina Harmuth et al. Frontiers in Molecular Neuroscience
- T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease
- (2018) Yoshikuni Tabata et al. Stem Cell Reports
- Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis
- (2017) Mireille Khacho et al. HUMAN MOLECULAR GENETICS
- SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila
- (2017) Alessandra Zanon et al. HUMAN MOLECULAR GENETICS
- Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling
- (2017) Daniel C. Berwick et al. Molecular Neurodegeneration
- Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease
- (2017) Kevin Richetin et al. NEUROBIOLOGY OF DISEASE
- Expanded and Wild-type Ataxin-3 Modify the Redox Status of SH-SY5Y Cells Overexpressing α-Synuclein
- (2017) Carolina Noronha et al. NEUROCHEMICAL RESEARCH
- Newborn dopaminergic neurons are associated with the migration and differentiation of SVZ-derived neural progenitors in a 6-hydroxydopamin-injected mouse model
- (2017) M.Q. Xie et al. NEUROSCIENCE
- αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson’s disease
- (2017) Victorio Martin Pozo Devoto et al. Scientific Reports
- S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models
- (2017) Chang-Ki Oh et al. Cell Reports
- A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity
- (2017) Marlen Knobloch et al. Cell Reports
- The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models
- (2017) Jung-Yu Hsu et al. Frontiers in Molecular Neuroscience
- Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation
- (2017) Patricia Martín-Maestro et al. Frontiers in Molecular Neuroscience
- Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells
- (2017) Xiaohong Xu et al. Stem Cell Reports
- Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism
- (2017) J.D. Gothié et al. Molecular Metabolism
- Adult neurogenesis and neurodegenerative diseases: A systems biology perspective
- (2016) Emrin Horgusluoglu et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function
- (2016) Lena Pernas et al. Annual Review of Physiology
- Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells
- (2016) Rita Perfeito et al. ARCHIVES OF TOXICOLOGY
- ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance
- (2016) Kun Liu et al. Autophagy
- Dysfunctional mitochondrial fission impairs cell reprogramming
- (2016) Javier Prieto et al. CELL CYCLE
- Metabolic reprogramming during neuronal differentiation
- (2016) M Agostini et al. CELL DEATH AND DIFFERENTIATION
- Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease
- (2016) Chung-Han Hsieh et al. Cell Stem Cell
- Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program
- (2016) Mireille Khacho et al. Cell Stem Cell
- 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis
- (2016) Inga B. Fricke et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- (R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model
- (2016) Yi-Hsin Weng et al. EXPERIMENTAL NEUROLOGY
- Loss of Mitochondrial Function Impairs Lysosomes
- (2016) Julie Demers-Lamarche et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Mitochondrial Basis of Aging
- (2016) Nuo Sun et al. MOLECULAR CELL
- Revisiting Mitochondrial Function and Metabolism in Pluripotent Stem Cells: Where Do We Stand in Neurological Diseases?
- (2016) Carla Lopes et al. MOLECULAR NEUROBIOLOGY
- Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells
- (2016) Carla Lopes et al. PLoS One
- Derivation, Characterization, and Neural Differentiation of Integration-Free Induced Pluripotent Stem Cell Lines from Parkinson’s Disease Patients Carrying SNCA, LRRK2, PARK2, and GBA Mutations
- (2016) Olga Momcilovic et al. PLoS One
- Energy metabolism in the acquisition and maintenance of stemness
- (2016) Clifford D.L. Folmes et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3
- (2016) Susanne K. Hansen et al. Stem Cell Research
- There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases
- (2016) Sebastien Paillusson et al. TRENDS IN NEUROSCIENCES
- Abnormal Development of Glutamatergic Synapses Afferent to Dopaminergic Neurons of the Pink1−/− Mouse Model of Parkinson’s Disease
- (2016) Edouard Pearlstein et al. Frontiers in Cellular Neuroscience
- Neurogenesis in the Developing and Adult Brain—Similarities and Key Differences
- (2016) Magdalena Götz et al. Cold Spring Harbor Perspectives in Biology
- Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
- (2016) Javier Prieto et al. Nature Communications
- Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
- (2016) Xinde Zheng et al. eLife
- Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity
- (2016) Jonathon Nixon-Abell et al. Frontiers in Molecular Neuroscience
- Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation
- (2016) Sun Young Chung et al. Stem Cell Reports
- Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness
- (2016) Alejandro Vazquez-Martin et al. Aging-US
- Structure and function of mitochondrial membrane protein complexes
- (2015) Werner Kühlbrandt BMC BIOLOGY
- Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons
- (2015) B Oettinghaus et al. CELL DEATH AND DIFFERENTIATION
- Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency
- (2015) M J Son et al. CELL DEATH AND DIFFERENTIATION
- Ghrelin is required for dietary restriction-induced enhancement of hippocampal neurogenesis: lessons from ghrelin knockout mice
- (2015) Yumi Kim et al. ENDOCRINE JOURNAL
- Regulation of mitochondrial transport in neurons
- (2015) Mei-Yao Lin et al. EXPERIMENTAL CELL RESEARCH
- Fatal infantile mitochondrial encephalomyopathy, hypertrophic cardiomyopathy and optic atrophy associated with a homozygousOPA1mutation
- (2015) Ronen Spiegel et al. JOURNAL OF MEDICAL GENETICS
- Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming
- (2015) Tianhua Ma et al. NATURE CELL BIOLOGY
- Proliferation control in neural stem and progenitor cells
- (2015) Catarina C. F. Homem et al. NATURE REVIEWS NEUROSCIENCE
- Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease–like pathology
- (2015) Wei Zhang et al. NEUROBIOLOGY OF AGING
- PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper
- (2015) Asad A. Aboud et al. NEUROBIOLOGY OF DISEASE
- Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
- (2015) P. Katajisto et al. SCIENCE
- Neural Stem Cells in the Adult Subventricular Zone Oxidize Fatty Acids to Produce Energy and Support Neurogenic Activity
- (2015) Elizabeth A. Stoll et al. STEM CELLS
- Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux
- (2015) Laura C. O'Brien et al. STEM CELLS AND DEVELOPMENT
- Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells
- (2015) L M A Oliveira et al. Cell Death & Disease
- Modulation of mitochondrial function by stem cell-derived cellular components
- (2014) Tian Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice
- (2014) Liliana S. Mendonça et al. BRAIN
- Ecdysone and Mediator Change Energy Metabolism to Terminate Proliferation in Drosophila Neural Stem Cells
- (2014) Catarina C.F. Homem et al. CELL
- Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency
- (2014) Julie Mathieu et al. Cell Stem Cell
- Polyglutamine (PolyQ) Diseases: Genetics to Treatments
- (2014) Hueng-Chuen Fan et al. CELL TRANSPLANTATION
- Mitochondrial Biogenesis: A Therapeutic Target for Neurodevelopmental Disorders and Neurodegenerative Diseases
- (2014) Martine Uittenbogaard et al. CURRENT PHARMACEUTICAL DESIGN
- Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells
- (2014) Ismail Ismailoglu et al. DEVELOPMENTAL BIOLOGY
- Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations
- (2014) P. A. Gammage et al. EMBO Molecular Medicine
- Age-related changes in astrocytic and ependymal cells of the subventricular zone
- (2014) Vivian Capilla-Gonzalez et al. GLIA
- Mitochondria Modify Exercise-Induced Development of Stem Cell-Derived Neurons in the Adult Brain
- (2014) K. Steib et al. JOURNAL OF NEUROSCIENCE
- Proteomics of Huntington’s Disease-Affected Human Embryonic Stem Cells Reveals an Evolving Pathology Involving Mitochondrial Dysfunction and Metabolic Disturbances
- (2014) Leon R. McQuade et al. JOURNAL OF PROTEOME RESEARCH
- Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells
- (2014) Rita Perfeito et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Inhibition of mitochondrial protein import by mutant huntingtin
- (2014) Hiroko Yano et al. NATURE NEUROSCIENCE
- Huntington’s disease: pathogenesis to animal models
- (2014) Puneet Kumar et al. Pharmacological Reports
- Higher Vulnerability and Stress Sensitivity of Neuronal Precursor Cells Carrying an Alpha-Synuclein Gene Triplication
- (2014) Adrian Flierl et al. PLoS One
- Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity
- (2014) Virve Kärkkäinen et al. STEM CELLS
- Drp1 Is Dispensable for Mitochondria Biogenesis in Induction to Pluripotency but Required for Differentiation of Embryonic Stem Cells
- (2014) Lei Wang et al. STEM CELLS AND DEVELOPMENT
- Neurogenesis in the embryonic and adult brain: same regulators, different roles
- (2014) Noelia Urbán et al. Frontiers in Cellular Neuroscience
- Defining the Role of Oxygen Tension in Human Neural Progenitor Fate
- (2014) Yuan Xie et al. Stem Cell Reports
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?
- (2013) Manoela Viar Fogaca et al. Current Neuropharmacology
- Alzheimer's disease-associated polymorphisms in human OGG1 alter catalytic activity and sensitize cells to DNA damage
- (2013) Kimberly D. Jacob et al. FREE RADICAL BIOLOGY AND MEDICINE
- Role of oxidative DNA damage in mitochondrial dysfunction and Huntington’s disease pathogenesis
- (2013) Sylvette Ayala-Peña FREE RADICAL BIOLOGY AND MEDICINE
- Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation
- (2013) Yu-Chin Su et al. HUMAN MOLECULAR GENETICS
- Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration
- (2013) Xing Guo et al. JOURNAL OF CLINICAL INVESTIGATION
- Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers
- (2013) Ana C. Silva et al. MITOCHONDRION
- Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs
- (2013) Sandra R Bacman et al. NATURE MEDICINE
- Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1−42 on neural progenitor cell proliferation
- (2013) Yan Hou et al. NEUROBIOLOGY OF AGING
- LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
- (2013) Laurie H. Sanders et al. NEUROBIOLOGY OF DISEASE
- Neural Stem Cells: Generating and Regenerating the Brain
- (2013) Fred H. Gage et al. NEURON
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling
- (2013) A. Kasahara et al. SCIENCE
- HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1-3 and PKM2
- (2013) Alessandro Prigione et al. STEM CELLS
- Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice
- (2012) Kati J. Ahlqvist et al. Cell Metabolism
- Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
- (2012) The HD iPSC Consortium Cell Stem Cell
- Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation
- (2012) Jing Wang et al. Cell Stem Cell
- Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells
- (2012) Mahru C. An et al. Cell Stem Cell
- Decreased NURR1 and PITX3 gene expression in Chinese patients with Parkinson’s disease
- (2012) H. Liu et al. EUROPEAN JOURNAL OF NEUROLOGY
- LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
- (2012) Daniel C. Berwick et al. HUMAN MOLECULAR GENETICS
- Defective mitochondrial disulfide relay system, altered mitochondrial morphology and function in Huntington's disease
- (2012) Eleonora Napoli et al. HUMAN MOLECULAR GENETICS
- Minocycline-Preconditioned Neural Stem Cells Enhance Neuroprotection after Ischemic Stroke in Rats
- (2012) H. Sakata et al. JOURNAL OF NEUROSCIENCE
- The link between the GBA gene and parkinsonism
- (2012) Ellen Sidransky et al. LANCET NEUROLOGY
- The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities
- (2012) Tatsunori Maekawa et al. Molecular Neurodegeneration
- Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
- (2012) Marlen Knobloch et al. NATURE
- Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology
- (2012) Elaine K. Perry et al. NEUROBIOLOGY OF DISEASE
- Patterns of Mitochondrial DNA Damage in Blood and Brain Tissues of a Transgenic Mouse Model of Machado-Joseph Disease
- (2012) Nadiya Kazachkova et al. Neurodegenerative Diseases
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
- (2012) Fumitaka Kawakami et al. PLoS One
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development
- (2012) Yan Hou et al. STEM CELLS
- Mitochondrial dynamics in neurodegeneration
- (2012) Kie Itoh et al. TRENDS IN CELL BIOLOGY
- Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines
- (2012) Aiwu Cheng et al. Nature Communications
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
- (2012) Yoichi Imaizumi et al. Molecular Brain
- Compromised mitochondrial complex II in models of Machado–Joseph disease
- (2011) Mário N. Laço et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain
- (2011) Simone A. van den Berge et al. BRAIN
- Calcium signaling around Mitochondria Associated Membranes (MAMs)
- (2011) Simone Patergnani et al. Cell Communication and Signaling
- Dopaminergic modulation of neurogenesis in the subventricular zone of the adult brain
- (2011) Gráinne C. O’Keeffe et al. CELL CYCLE
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner
- (2011) Janel E. Le Belle et al. Cell Stem Cell
- Pathoanatomy of Cerebellar Degeneration in Spinocerebellar Ataxia Type 2 (SCA2) and Type 3 (SCA3)
- (2011) W. Scherzed et al. CEREBELLUM
- Aging Neural Progenitor Cells Have Decreased Mitochondrial Content and Lower Oxidative Metabolism
- (2011) Elizabeth A. Stoll et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein
- (2011) Ken Nakamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate
- (2011) W. Wang et al. JOURNAL OF NEUROSCIENCE
- Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
- (2011) Philipp Koch et al. NATURE
- Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's disease
- (2011) Lifen Zhang et al. NEUROBIOLOGY OF AGING
- Leucine-Rich Repeat Kinase 2 Modulates Retinoic Acid-Induced Neuronal Differentiation of Murine Embryonic Stem Cells
- (2011) Cathrin Schulz et al. PLoS One
- Coordinate Regulation of Neurite Outgrowth by LRRK2 and Its Interactor, Rab5
- (2011) Hye Young Heo et al. Experimental Neurobiology
- Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease
- (2010) Jun Peng et al. AGING CELL
- Mitochondria and Huntington's Disease Pathogenesis
- (2010) Susan E. Browne Annals of the New York Academy of Sciences
- Preventing NAD+ Depletion Protects Neurons against Excitotoxicity
- (2010) Dong Liu et al. Annals of the New York Academy of Sciences
- Somatic Mitochondrial DNA Mutations in Mammalian Aging
- (2010) Nils-Göran Larsson Annual Review of Biochemistry
- Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
- (2010) P. Hemachandra Reddy et al. BRAIN RESEARCH REVIEWS
- The mtDNA Mutation Spectrum of the Progeroid Polg Mutator Mouse Includes Abundant Control Region Multimers
- (2010) Siôn L. Williams et al. Cell Metabolism
- Mutant huntingtin-impaired degradation of β-catenin causes neurotoxicity in Huntington's disease
- (2010) Juliette D Godin et al. EMBO JOURNAL
- Impaired dopaminergic neuron development and locomotor function in zebrafish with loss ofpink1function
- (2010) Yanwei Xi et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer’s disease
- (2010) Laura K. Hamilton et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Mitochondrial-dependent apoptosis in Huntington's disease human cybrids
- (2010) Ildete L. Ferreira et al. EXPERIMENTAL NEUROLOGY
- The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
- (2010) Thomas M. Durcan et al. HUMAN MOLECULAR GENETICS
- Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development
- (2010) Sabrina Zechel et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice
- (2010) Michael Demars et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- A mitochondrial ubiquitin ligase MITOL controls cell toxicity of polyglutamine-expanded protein
- (2010) Ayumu Sugiura et al. MITOCHONDRION
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
- (2010) B. Winner et al. NEUROBIOLOGY OF DISEASE
- Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease
- (2010) Jessica M. Simpson et al. NEUROBIOLOGY OF DISEASE
- Expression of Familial Alzheimer’s Disease-Linked Human Presenilin 1 Variants Impair Enrichment-Induced Adult Hippocampal Neurogenesis
- (2010) Karthikeyan Veeraraghavalu et al. Neurodegenerative Diseases
- Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis
- (2010) Juliette D. Godin et al. NEURON
- A comparative study of Lrrk2 function in primary neuronal cultures
- (2010) Justus C. Dächsel et al. PARKINSONISM & RELATED DISORDERS
- Mitochondrial DNA Integrity Is Essential For Mitochondrial Maturation During Differentiation of Neural Stem Cells
- (2010) Wei Wang et al. STEM CELLS
- Professional exposure to pesticides and Parkinson disease
- (2009) Alexis Elbaz et al. ANNALS OF NEUROLOGY
- The Glial Nature of Embryonic and Adult Neural Stem Cells
- (2009) Arnold Kriegstein et al. Annual Review of Neuroscience
- Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease
- (2009) Rodrigo A. Quintanilla et al. BRAIN RESEARCH BULLETIN
- Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options
- (2009) Bayani Uttara et al. Current Neuropharmacology
- Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model
- (2009) Beate Winner et al. EXPERIMENTAL NEUROLOGY
- Nrf2 promotes neuronal cell differentiation
- (2009) Fei Zhao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways
- (2009) Rosa M. Sancho et al. HUMAN MOLECULAR GENETICS
- The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
- (2009) Junko Wakabayashi et al. JOURNAL OF CELL BIOLOGY
- Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
- (2009) L. Parisiadou et al. JOURNAL OF NEUROSCIENCE
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease
- (2009) Dietrich Haubenberger et al. NEUROBIOLOGY OF AGING
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The biology of PGC-1α and its therapeutic potential
- (2009) Christoph Handschin TRENDS IN PHARMACOLOGICAL SCIENCES
- Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington’s disease patients
- (2008) Sandra Almeida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- OPA1 mutations and mitochondrial DNA damage: keeping the magic circle in shape
- (2008) M. Zeviani BRAIN
- Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease
- (2008) Fiona E. O’Keeffe et al. BRAIN
- Mitochondrial association of alpha-synuclein causes oxidative stress
- (2008) M. S. Parihar et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus
- (2008) Bin Li et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease
- (2008) S. Nuber et al. JOURNAL OF NEUROSCIENCE
- N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking
- (2008) A. L. Orr et al. JOURNAL OF NEUROSCIENCE
- Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish
- (2008) O. Anichtchik et al. JOURNAL OF NEUROSCIENCE
- Optical Reporters for the Conformation of -Synuclein Reveal a Specific Interaction with Mitochondria
- (2008) K. Nakamura et al. JOURNAL OF NEUROSCIENCE
- -Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice
- (2008) L. Crews et al. JOURNAL OF NEUROSCIENCE
- Decreased NURR1 gene expression in patients with Parkinson's disease
- (2008) Weidong Le et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain
- (2008) Itaru Imayoshi et al. NATURE NEUROSCIENCE
- PITX3 polymorphism is associated with early onset Parkinson's disease
- (2008) Olle Bergman et al. NEUROBIOLOGY OF AGING
- Mutant α-synuclein exacerbates age-related decrease of neurogenesis
- (2007) Beate Winner et al. NEUROBIOLOGY OF AGING
- The transcription factor PITX3 is associated with sporadic Parkinson's disease
- (2007) Julia Fuchs et al. NEUROBIOLOGY OF AGING
- Adult neurogenesis is functionally associated with AD-like neurodegeneration
- (2007) Qian Chen et al. NEUROBIOLOGY OF DISEASE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started