The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities

LRRK2: A Problem Lurking in Vesicle Trafficking?

(2011) S. Dihanich et al.   JOURNAL OF NEUROSCIENCE

LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool

(2011) G. Piccoli et al.   JOURNAL OF NEUROSCIENCE

Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2

(2011) David Ramonet et al.   PLoS One

Structural organization of the Golgi apparatus

(2010) Martin Lowe   CURRENT OPINION IN CELL BIOLOGY

LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of the Drosophila Neuromuscular Junction

(2010) S. Lee et al.   JOURNAL OF NEUROSCIENCE

A rotarod test for evaluation of motor skill learning

(2010) Hiromi Shiotsuki et al.   JOURNAL OF NEUROSCIENCE METHODS

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

(2010) H.L. Melrose et al.   NEUROBIOLOGY OF DISEASE

A comparative study of Lrrk2 function in primary neuronal cultures

(2010) Justus C. Dächsel et al.   PARKINSONISM & RELATED DISORDERS

I2020T leucine-rich repeat kinase 2, the causative mutant molecule of familial Parkinson’s disease, has a higher intracellular degradation rate than the wild-type molecule

(2009) Etsuro Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis

(2009) Etsuro Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LRRK2 in Parkinson’s disease: function in cells and neurodegeneration

(2009) Philip J. Webber et al.   FEBS Journal

Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

(2009) K. Venderova et al.   HUMAN MOLECULAR GENETICS

Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation

(2009) Javorina Milosevic et al.   Molecular Neurodegeneration

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

(2009) Xian Lin et al.   NEURON

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice

(2009) Y. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

(2008) Yuzuru Imai et al.   EMBO JOURNAL

LRRK2 regulates synaptic vesicle endocytosis

(2008) Narae Shin et al.   EXPERIMENTAL CELL RESEARCH

Familial parkinsonism: Study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes

(2008) Kazuko Hasegawa et al.   PARKINSONISM & RELATED DISORDERS