Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells

Published 2017 View Full Article

Authors

Keywords

human induced pluripotent stem cell (hiPSC), neurodegenerative disorders, Huntington disease, genetic editing, disease modeling, disease phenotypes, transcriptional dysrgulation, CHCHD2, mitochondrial dysfunction

Journal

Stem Cell Reports

Volume 8, Issue 3, Pages 619-633

Publisher

Elsevier BV

Online

2017-02-24

DOI

10.1016/j.stemcr.2017.01.022

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