Regulatory roles of external cholesterol in human airway epithelial mitochondrial function through STARD3 signalling

DKK1 Positively Correlates with Lung Function in COPD Patients and Reduces Airway Inflammation

(2022) Luqi Dai et al.   International Journal of Chronic Obstructive Pulmonary Disease

Clinical challenges of tissue preparation for spatial transcriptome

(2022) Xiaoxia Liu et al.   Clinical and Translational Medicine

Cigarette smoking exposure breaks the homeostasis of cholesterol and bile acid metabolism and induces gut microbiota dysbiosis in mice with different diets

(2021) Yanhong Yang et al.   TOXICOLOGY

Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation

(2021) Nicholas Jones et al.   Nature Communications

Altered lipidomic profiles in patients with and without osteonecrosis of the femoral head after 1‐month glucocorticoid treatment

(2021) Xin‐Yuan Wang et al.   Clinical and Translational Medicine

Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD

(2021) Yue Yang et al.   BMC Pulmonary Medicine

Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish

(2021) Si-Lan Han et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mitochondrial Dysfunction in Chronic Respiratory Diseases: Implications for the Pathogenesis and Potential Therapeutics

(2021) Wen-cheng Zhou et al.   Oxidative Medicine and Cellular Longevity

miR-937 serves as an inflammatory inhibitor in cigarette smoke extract-induced human bronchial epithelial cells by targeting IL1B and regulating TNF-α/IL-17 signaling pathway

(2021) Teng Liu   Tobacco Induced Diseases

ST6GAL1 and α2-6 Sialylation Regulates IL-6 Expression and Secretion in Chronic Obstructive Pulmonary Disease

(2021) Stefanie Krick et al.   Frontiers in Immunology

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation

(2021) Sandra Torres et al.   Redox Biology

Role of inner mitochondrial protein OPA1 in mitochondrial dysfunction by tobacco smoking and in the pathogenesis of COPD

(2021) Krishna Prahlad Maremanda et al.   Redox Biology

Potential biomarkers and targets of mitochondrial dynamics

(2021) Liyang Li et al.   Clinical and Translational Medicine

Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes

(2021) Ming Wang et al.   iScience

No Independent Influence of Statins on the Chronic Obstructive Pulmonary Disease Exacerbation Rate: A Cohort Observation Study Over 10 Years

(2021) Josef Yayan et al.   International Journal of General Medicine

Mitochondrial dynamics and mitophagy in lung disorders

(2021) Archana Sharma et al.   LIFE SCIENCES

New focuses on roles of communications between endoplasmic reticulum and mitochondria in identification of biomarkers and targets

(2021) Linlin Zhang et al.   Clinical and Translational Medicine

Roles of acyl-CoA synthetase long-chain family member 5 and colony stimulating factor 2 in inhibition of palmitic or stearic acids in lung cancer cell proliferation and metabolism

(2020) Linlin Zhang et al.   CELL BIOLOGY AND TOXICOLOGY

Mitochondrial Fission Mediated Cigarette Smoke-induced Pulmonary Endothelial Injury

(2020) Zhengke Wang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress

(2020) Xiang Cheng et al.   Cell Metabolism

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen

(2020) Santosha A. Vardhana et al.   NATURE IMMUNOLOGY

Identification of required host factors for SARS-CoV-2 infection in human cells

(2020) Zharko Daniloski et al.   CELL

Sirtuin 3 Inhibits Airway Epithelial Mitochondrial Oxidative Stress in Cigarette Smoke-Induced COPD

(2020) Ming Zhang et al.   Oxidative Medicine and Cellular Longevity

Global Immunometabolic Profiling of AECOPD

(2020) Dongli Song et al.   Small Methods

Trans‐omic profiling between clinical phenoms and lipidomes among patients with different subtypes of lung cancer

(2020) Zhenhua Zhu et al.   Clinical and Translational Medicine

Long non‑coding RNA maternally expressed gene regulates cigarette smoke extract induced lung inflammation and human bronchial epithelial apoptosis via miR‑149‑3p

(2020) Zhenwu Lei et al.   Experimental and Therapeutic Medicine

MiR-218 Inhibits CSE-Induced Apoptosis and Inflammation in BEAS-2B by Targeting BRD4

(2020) Xiaoli Liu et al.   International Journal of Chronic Obstructive Pulmonary Disease

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

(2019) Ilias Angelidis et al.   Nature Communications

Values of integration between lipidomics and clinical phenomes in patients with acute lung infection, pulmonary embolism, or acute exacerbation of chronic pulmonary diseases: a preliminary study

(2019) Danyan Gao et al.   Journal of Translational Medicine

Lipid metabolism in chronic obstructive pulmonary disease

(2019) Haipin Chen et al.   International Journal of Chronic Obstructive Pulmonary Disease

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity

(2019) Philipp Hammerschmidt et al.   CELL

Mitochondrial dynamics modulation as a critical contribution for Shenmai injection in attenuating hypoxia/reoxygenation injury

(2019) Jiahui Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mitochondrial fusion regulates lipid homeostasis and stem cell maintenance in the Drosophila testis

(2019) Rafael Sênos Demarco et al.   NATURE CELL BIOLOGY

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis

(2019) Kuei-Pin Chung et al.   Nature Communications

Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes

(2019) Estel Solsona-Vilarrasa et al.   Redox Biology

Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease

(2019) Bartolomé R. Celli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease

(2019) Mahyar Aghapour et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Single‐cell high content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells

(2019) Justyna M. Kowal et al.   Stem Cells Translational Medicine

Clinical lipidomics in understanding of lung cancer: Opportunity and challenge

(2019) Linlin Zhang et al.   CANCER LETTERS

Mechanisms and regulation of cholesterol homeostasis

(2019) Jie Luo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells

(2018) Xiaoqian Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease

(2018) Jie Jia et al.   EMBO Molecular Medicine

Heterogeneity of lipidomic profiles among lung cancer subtypes of patients

(2018) Jiapei Lv et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Is the clinical lipidomics a potential goldmine?

(2018) Linlin Zhang et al.   CELL BIOLOGY AND TOXICOLOGY

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease

(2017) Patricia Martín-Maestro et al.   Oxidative Medicine and Cellular Longevity

Investigation of the derivatization conditions for GC–MS metabolomics of biological samples

(2017) Georgios Moros et al.   Bioanalysis

MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

(2017) Elisa Balboa et al.   Redox Biology

Restoration of Corticosteroid Sensitivity in Chronic Obstructive Pulmonary Disease by Inhibition of Mammalian Target of Rapamycin

(2016) Akihisa Mitani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

ABCA3 protects alveolar epithelial cells against free cholesterol induced cell death

(2015) Ralf Zarbock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice

(2015) Mathieu C. Morissette et al.   EUROPEAN RESPIRATORY JOURNAL

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

(2015) Albert Herms et al.   Nature Communications

Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function

(2014) Laura A. Martin et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Simvastatin for the Prevention of Exacerbations in Moderate-to-Severe COPD

(2014) Gerard J. Criner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Steroid hormone synthesis in mitochondria

(2013) Walter L. Miller   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation

(2012) Kenta Kuramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY