Single-cell RNA sequencing of subcutaneous adipose tissues identifies therapeutic targets for cancer-associated lymphedema

Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis

(2021) Amir Boufenzer et al.   Cellular & Molecular Immunology

Confronting false discoveries in single-cell differential expression

(2021) Jordan W. Squair et al.   Nature Communications

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

(2020) Joanna Kalucka et al.   CELL

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

Transcriptome analysis and functional identification of adipose-derived mesenchymal stem cells in secondary lymphedema

(2020) Qinqin Xiang et al.   Gland Surgery

TREM-1 orchestrates angiotensin II–induced monocyte trafficking and promotes experimental abdominal aortic aneurysm

(2020) Marie Vandestienne et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer-associated secondary lymphoedema

(2019) Stanley G. Rockson et al.   Nature Reviews Disease Primers

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

(2019) Christian F. Guerrero-Juarez et al.   Nature Communications

Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer

(2019) Sunil Singhal et al.   Science Translational Medicine

Glycosylation in health and disease

(2019) Colin Reily et al.   Nature Reviews Nephrology

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

(2019) Evan Der et al.   NATURE IMMUNOLOGY

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury

(2019) Nona Farbehi et al.   eLife

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

A cellular census of human lungs identifies novel cell states in health and in asthma

(2019) Felipe A. Vieira Braga et al.   NATURE MEDICINE

Beyond bulk: a review of single cell transcriptomics methodologies and applications

(2019) Ashwinikumar Kulkarni et al.   CURRENT OPINION IN BIOTECHNOLOGY

OUP accepted manuscript

(2018)   BIOINFORMATICS

Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling

(2018) Rayanne B. Burl et al.   Cell Metabolism

PDGF-C and PDGF-D signaling in vascular diseases and animal models

(2018) Erika Folestad et al.   MOLECULAR ASPECTS OF MEDICINE

Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing

(2018) Xinyi Guo et al.   NATURE MEDICINE

Microvascular Mural Cell Organotypic Heterogeneity and Functional Plasticity

(2018) Annegret Holm et al.   TRENDS IN CELL BIOLOGY

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

(2018) Hwee Ying Lim et al.   IMMUNITY

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice

(2018) Chelsea Hepler et al.   eLife

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

(2018) Paul A Reyfman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Adipose-derived stem cells were impaired in restricting CD4 + T cell proliferation and polarization in type 2 diabetic ApoE −/− mouse

(2017) Ming-hao Liu et al.   MOLECULAR IMMUNOLOGY

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Differential analysis of RNA-seq incorporating quantification uncertainty

(2017) Harold Pimentel et al.   NATURE METHODS

The Adipose Stromal Vascular Fraction as a Complex Cellular Source for Tissue Engineering Applications

(2017) Venkat M. Ramakrishnan et al.   TISSUE ENGINEERING PART B-REVIEWS

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Genetic and Pharmacological Inhibition of TREM-1 Limits the Development of Experimental Atherosclerosis

(2016) Jeremie Joffre et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

DNA Damage: From Chronic Inflammation to Age-Related Deterioration

(2016) Anna Ioannidou et al.   Frontiers in Genetics

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

FOXP3+ regulatory T cells and their functional regulation

(2015) Zhiyuan Li et al.   Cellular & Molecular Immunology

Antioxidant metallothionein alleviates endoplasmic reticulum stress-induced myocardial apoptosis and contractile dysfunction

(2015) L. Yang et al.   FREE RADICAL RESEARCH

Identification of aPrg4-Expressing Articular Cartilage Progenitor Cell Population in Mice

(2015) Elena Kozhemyakina et al.   Arthritis & Rheumatology

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Recent progress in the treatment and prevention of cancer-related lymphedema

(2014) Simona F. Shaitelman et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Lymphedema and Obesity

(2014) Babak J. Mehrara et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Adipose-derived mesenchymal stromal/stem cells: An update on their phenotype in vivo and in vitro

(2014) Patrick C Baer   World Journal of Stem Cells

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

The Role of Metallothionein in Oxidative Stress

(2013) Branislav Ruttkay-Nedecky et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis

(2013) Tracey DiSipio et al.   LANCET ONCOLOGY

Molecular Analysis and Differentiation Capacity of Adipose-Derived Stem Cells from Lymphedema Tissue

(2013) Benjamin Levi et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Regulation of Adipogenesis by Lymphatic Fluid Stasis

(2012) Seth Aschen et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Regulation of Adipogenesis by Lymphatic Fluid Stasis

(2012) Jamie C. Zampell et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

CD4+ Cells Regulate Fibrosis and Lymphangiogenesis in Response to Lymphatic Fluid Stasis

(2012) Jamie C. Zampell et al.   PLoS One

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

(2011) D. A. Hume et al.   BLOOD

Decrease in natural killer cell associated gene expression as a major characteristic of the immune status in the bloodstream of colorectal cancer patients

(2011) Ye Xu et al.   CANCER BIOLOGY & THERAPY

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathway Analysis of Expression Data: Deciphering Functional Building Blocks of Complex Diseases

(2011) Frank Emmert-Streib et al.   PLoS Computational Biology

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Lymphedema: A primer on the identification and management of a chronic condition in oncologic treatment

(2009) B. D. Lawenda et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PDGF-D Signaling: A Novel Target in Cancer Therapy

(2009) Zhiwei Wang et al.   CURRENT DRUG TARGETS

Functional Implications of CD34 Expression in Human Adipose–Derived Stem/Progenitor Cells

(2009) Hirotaka Suga et al.   STEM CELLS AND DEVELOPMENT