Pragmatic Expectancy on Microbiota and Non-Small Cell Lung Cancer: A Narrative Review

A comprehensive analysis of intratumor microbiome in head and neck squamous cell carcinoma

(2022) Yangyang Wang et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Matrix Metalloproteinases in Helicobacter pylori–Associated Gastritis and Gastric Cancer

(2022) Olga Sokolova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The airway microbiota of non‐small cell lung cancer patients and its relationship to tumor stage and EGFR gene mutation

(2022) Dan Hui Huang et al.   Thoracic Cancer

Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Progress, Challenges, and Prospects

(2022) Shengjie Tang et al.   Cells

Intratumor Microbiome in Neuroendocrine Neoplasms: A New Partner of Tumor Microenvironment? A Pilot Study

(2022) Sara Massironi et al.   Cells

Cancer's second genome: Microbial cancer diagnostics and redefining clonal evolution as a multispecies process

(2022) Gregory D. Sepich‐Poore et al.   BIOESSAYS

Dynamic liquid biopsy components as predictive and prognostic biomarkers in colorectal cancer

(2022) Afsheen Raza et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

(2022) Saife N. Lone et al.   Molecular Cancer

Predicting cancer prognosis and drug response from the tumor microbiome

(2022) Leandro C. Hermida et al.   Nature Communications

Lung microbiota features of stage III and IV non-small cell lung cancer patients without lung infection

(2022) Miao Zhang et al.   Translational Cancer Research

Direct Targeting KRAS Mutation in Non-Small Cell Lung Cancer: Focus on Resistance

(2022) Damien Reita et al.   Cancers

The role of hypoxia in the tumor microenvironment and development of cancer stem cell: a novel approach to developing treatment

(2021) Asieh Emami Nejad et al.   Cancer Cell International

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

(2021) Se-Hoon Lee et al.   Nature Microbiology

Tumor-Associated Microbiome: Where Do We Stand?

(2021) Marc Oliva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Beyond immune checkpoint blockade: emerging immunological strategies

(2021) Shawn P. Kubli et al.   NATURE REVIEWS DRUG DISCOVERY

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

(2021) Diwakar Davar et al.   SCIENCE

Identification of Tumor Tissue of Origin with RNA-Seq Data and Using Gradient Boosting Strategy

(2021) Ruixi Li et al.   Biomed Research International

New Insights Into the Cancer–Microbiome–Immune Axis: Decrypting a Decade of Discoveries

(2021) Tejeshwar Jain et al.   Frontiers in Immunology

Stem Cell Impairment at the Host-Microbiota Interface in Colorectal Cancer

(2021) Marinella Marzano et al.   Cancers

Non-small cell lung cancer microbiota characterization: Prevalence of enteric and potentially pathogenic bacteria in cancer tissues

(2021) Nathan Dumont-Leblond et al.   PLoS One

Immunomodulation by the Commensal Microbiome During Immune-Targeted Interventions: Focus on Cancer Immune Checkpoint Inhibitor Therapy and Vaccination

(2021) Abigail L. Reens et al.   Frontiers in Immunology

Investigating efficacy of “microbiota modulation of the gut-lung Axis” combined with chemotherapy in patients with advanced NSCLC: study protocol for a multicenter, prospective, double blind, placebo controlled, randomized trial

(2021) Qing Xia et al.   BMC CANCER

Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer

(2021) Justin Chau et al.   BMC CANCER

Exposure to a mixture of cigarette smoke carcinogens disturbs gut microbiota and influences metabolic homeostasis in A/J mice

(2021) Zhuo Qu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dissecting the Interplay Mechanism between Epigenetics and Gut Microbiota: Health Maintenance and Disease Prevention

(2021) Yuqi Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of lung and gut microbiota on lung cancer pathogenesis

(2021) Yue Zhao et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Association predictions of genomics, proteinomics, transcriptomics, microbiome, metabolomics, pathomics, radiomics, drug, symptoms, environment factor, and disease networks: A comprehensive approach

(2021) Yi Pan et al.   MEDICINAL RESEARCH REVIEWS

Selecting the optimal immunotherapy regimen in driver-negative metastatic NSCLC

(2021) Michael J. Grant et al.   Nature Reviews Clinical Oncology

Microbiome dysbiosis and epigenetic modulations in lung cancer: from pathogenesis to therapy

(2021) Faizan Haider Khan et al.   SEMINARS IN CANCER BIOLOGY

Microbial dysbiosis and epigenetics modulation in cancer development – A chemopreventive approach

(2021) Shafiul Haque et al.   SEMINARS IN CANCER BIOLOGY

Lung microbiome alterations in NSCLC patients

(2021) Leliang Zheng et al.   Scientific Reports

Conversion from epithelial to partial-EMT phenotype by Fusobacterium nucleatum infection promotes invasion of oral cancer cells

(2021) Wenhua Shao et al.   Scientific Reports

The Interaction Between the Microbiome and Tumors

(2021) Yawen Zong et al.   Frontiers in Cellular and Infection Microbiology

Host-Microbiome Interaction in Lung Cancer

(2021) Qiang Dong et al.   Frontiers in Immunology

The role of gut microbiome in modulating response to immune checkpoint inhibitor therapy in cancer

(2021) Abdul Rafeh Naqash et al.   Annals of Translational Medicine

Antigen-Presenting Cells in the Airways: Moderating Asymptomatic Bacterial Carriage

(2021) Lisa J. M. Slimmen et al.   Pathogens

The composition of lung microbiome in lung cancer: a systematic review and meta-analysis

(2021) Sadaf Najafi et al.   BMC MICROBIOLOGY

Circulating microbiome DNA: An emerging paradigm for cancer liquid biopsy

(2021) Haiming Chen et al.   CANCER LETTERS

Fusobacterium nucleatum promotes epithelial‐mesenchymal transiton through regulation of the lncRNA MIR4435‐2HG/miR‐296‐5p/Akt2/SNAI1 signaling pathway

(2020) Shuwei Zhang et al.   FEBS Journal

The growth of non-solid neoplastic lung nodules is associated with low PD L1 expression, irrespective of sampling technique

(2020) Chandra Bortolotto et al.   Journal of Translational Medicine

Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

(2020) Yulia Rubanova et al.   Nature Communications

The Gut-Lung Axis in Health and Respiratory Diseases: A Place for Inter-Organ and Inter-Kingdom Crosstalks

(2020) Raphaël Enaud et al.   Frontiers in Cellular and Infection Microbiology

Airway Microbiota as a Modulator of Lung Cancer

(2020) Taichiro Goto   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Microbiome analyses of blood and tissues suggest cancer diagnostic approach

(2020) Gregory D. Poore et al.   NATURE

Lineage plasticity in cancer: a shared pathway of therapeutic resistance

(2020) Álvaro Quintanal-Villalonga et al.   Nature Reviews Clinical Oncology

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

(2020) Deborah Nejman et al.   SCIENCE

Nutritional Exchanges Within Tumor Microenvironment: Impact for Cancer Aggressiveness

(2020) Giuseppina Comito et al.   Frontiers in Oncology

Efficacy of modified cell block cytology compared to fine needle aspiration cytology for diagnostic oral cytopathology

(2020) M. S. Sale et al.   BIOTECHNIC & HISTOCHEMISTRY

Tumor microenvironment in gastric cancers

(2020) Yukiko Oya et al.   CANCER SCIENCE

Microbiome definition re-visited: old concepts and new challenges

(2020) Gabriele Berg et al.   Microbiome

From Interconnection between Genes and Microenvironment to Novel Immunotherapeutic Approaches in Upper Gastro-Intestinal Cancers—A Multidisciplinary Perspective

(2020) Giulia Accordino et al.   Cancers

The Role of the Microbiome in Cancer and Therapy Efficacy: Focus on Lung Cancer

(2020) ADRIENNE HALLEY et al.   ANTICANCER RESEARCH

The relationship between KRAS gene mutation and intestinal flora in tumor tissues of colorectal cancer patients

(2020) Xinke Sui et al.   Annals of Translational Medicine

Microbiome-Derived Liquid Biopsy: New Hope for Cancer Screening?

(2020) Rachel C Newsome et al.   CLINICAL CHEMISTRY

Cancer and the Microbiome—Influence of the Commensal Microbiota on Cancer, Immune Responses, and Immunotherapy

(2020) Vyara Matson et al.   GASTROENTEROLOGY

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

(2020) Erez N. Baruch et al.   SCIENCE

Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma

(2020) Siwei Wang et al.   Nature Communications

Microbiome dysbiosis in lung cancer: from composition to therapy

(2020) Ning-Ning Liu et al.   npj Precision Oncology

The microbiome, cancer, and cancer therapy

(2019) Beth A. Helmink et al.   NATURE MEDICINE

Exploring the emerging role of the microbiome in cancer immunotherapy

(2019) Jessica Fessler et al.   Journal for ImmunoTherapy of Cancer

Smoking and microbiome in oral, airway, gut and some systemic diseases

(2019) Chunrong Huang et al.   Journal of Translational Medicine

Lung-Seeking Metastases

(2019) Giulia M. Stella et al.   Cancers

Whole genome sequencing revealed microbiome in lung adenocarcinomas presented as ground-glass nodules

(2019) Yijiu Ren et al.   Translational Lung Cancer Research

Differential Helicobacter pylori Plasticity in the Gastric Niche of Subjects at Increased Gastric Cancer Risk

(2019) Mariateresa Casarotto et al.   Pathogens

The characteristics of gut microbiota and commensal Enterobacteriaceae isolates in tree shrew (Tupaia belangeri)

(2019) Wenpeng Gu et al.   BMC MICROBIOLOGY

KRAS-Driven Metabolic Rewiring Reveals Novel Actionable Targets in Cancer

(2019) Emanuela Pupo et al.   Frontiers in Oncology

The Cancer Microbiota: EMT and Inflammation as Shared Molecular Mechanisms Associated with Plasticity and Progression

(2019) Daniele Vergara et al.   Journal of Oncology

Bacterial particles retard tumor growth as a novel vascular disrupting agent

(2019) Fengzhu Guo et al.   BIOMEDICINE & PHARMACOTHERAPY

Airway Microbiota Is Associated with Up-Regulation of the PI3K Pathway in Lung Cancer

(2018) Jun-Chieh J Tsay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interplay between the lung microbiome and lung cancer

(2018) Qixing Mao et al.   CANCER LETTERS

Perspective on immune oncology with liquid biopsy, peripheral blood mononuclear cells, and microbiome with non-invasive biomarkers in cancer patients

(2018) A. Mitsuhashi et al.   Clinical & Translational Oncology

Gut microbiome modulates efficacy of immune checkpoint inhibitors

(2018) Ming Yi et al.   Journal of Hematology & Oncology

Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies

(2018) Concetta Panebianco et al.   Microbiome

The role of the lung microbiota and the gut-lung axis in respiratory infectious diseases

(2018) Alexia Dumas et al.   CELLULAR MICROBIOLOGY

Colonocyte metabolism shapes the gut microbiota

(2018) Yael Litvak et al.   SCIENCE

Intrathoracic core needle biopsy and repeat biopsy for PD-L1 evaluation in non-small cell lung cancer

(2018) Giulia Maria Stella et al.   Journal of Thoracic Disease

Dysbiosis of the Salivary Microbiome Is Associated With Non-smoking Female Lung Cancer and Correlated With Immunocytochemistry Markers

(2018) Junjie Yang et al.   Frontiers in Oncology

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

The microbiota of the respiratory tract: gatekeeper to respiratory health

(2017) Wing Ho Man et al.   NATURE REVIEWS MICROBIOLOGY

Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer

(2017) Scott J. Antonia et al.   NEW ENGLAND JOURNAL OF MEDICINE

The microbiome and the hallmarks of cancer

(2017) Laura E. Fulbright et al.   PLoS Pathogens

MET Activation and Physical Dynamics of the Metastatic Process: The Paradigm of Cancers of Unknown Primary Origin

(2017) Giulia M. Stella et al.   EBioMedicine

Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome

(2017) Marion Engel et al.   PLoS One

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

(2016) Gerard E. Kaiko et al.   CELL

Cigarette smoking and the oral microbiome in a large study of American adults

(2016) Jing Wu et al.   ISME Journal

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

(2016) Sebastian Moran et al.   LANCET ONCOLOGY

The respiratory tract microbiome and lung inflammation: a two-way street

(2016) G B Huffnagle et al.   Mucosal Immunology

Comprehensive description of blood microbiome from healthy donors assessed by 16S targeted metagenomic sequencing

(2016) Sandrine Païssé et al.   TRANSFUSION

Epigenetics in lung cancer diagnosis and therapy

(2015) Aditi Mehta et al.   CANCER AND METASTASIS REVIEWS

Synthetic long-read sequencing reveals intraspecies diversity in the human microbiome

(2015) Volodymyr Kuleshov et al.   NATURE BIOTECHNOLOGY

Lineage factors and differentiation states in lung cancer progression

(2015) W K C Cheung et al.   ONCOGENE

Vasculature Disruption Enhances Bacterial Targeting of Autochthonous Tumors

(2015) Jeremy J. Drees et al.   Journal of Cancer

The Niche Component Periostin Is Produced by Cancer-Associated Fibroblasts, Supporting Growth of Gastric Cancer through ERK Activation

(2014) Yoshinao Kikuchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect

(2014) Xingmin Wang et al.   GUT

An introduction to the analysis of shotgun metagenomic data

(2014) Thomas J. Sharpton   Frontiers in Plant Science

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Effect of Probiotics Lactobacillus and Bifidobacterium on Gut-Derived Lipopolysaccharides and Inflammatory Cytokines: An In Vitro Study Using a Human Colonic Microbiota Model

(2013) Laetitia Rodes   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Liquid biopsy: monitoring cancer-genetics in the blood

(2013) Emily Crowley et al.   Nature Reviews Clinical Oncology

Analysis of the Airway Microbiota of Healthy Individuals and Patients with Chronic Obstructive Pulmonary Disease by T-RFLP and Clone Sequencing

(2013) Tetyana Zakharkina et al.   PLoS One

Lung cancer survival and stage at diagnosis in Australia, Canada, Denmark, Norway, Sweden and the UK: a population-based study, 2004–2007

(2013) Sarah Walters et al.   THORAX

Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells

(2013) Z Zhang et al.   Cell Death & Disease

Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications

(2013) Elza C de Bruin et al.   Genome Medicine

Oncogenes in non-small-cell lung cancer: emerging connections and novel therapeutic dynamics

(2013) Giulia M Stella et al.   Lancet Respiratory Medicine

Lung carcinogenesis by tobacco smoke

(2012) Stephen S. Hecht   INTERNATIONAL JOURNAL OF CANCER

Effectiveness of the cell block technique in diagnostic cytopathology

(2012) Shehnaz Khan et al.   Journal of Cytology

Defining the human microbiome

(2012) Luke K Ursell et al.   NUTRITION REVIEWS

Bioinformatics for the Human Microbiome Project

(2012) Dirk Gevers et al.   PLoS Computational Biology

Impact of cigarette smoke exposure on host-bacterial pathogen interactions

(2011) J. Garmendia et al.   EUROPEAN RESPIRATORY JOURNAL

Gene therapy for cancer: bacteria-mediated anti-angiogenesis therapy

(2011) R Gardlik et al.   GENE THERAPY

Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity

(2011) Yann Fardini et al.   MOLECULAR MICROBIOLOGY

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

(2011) A. C. Goodwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting EGFR in non-small-cell lung cancer: Lessons, experiences, strategies

(2011) Giulia M. Stella et al.   RESPIRATORY MEDICINE

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

(2010) L. E. Wroblewski et al.   CLINICAL MICROBIOLOGY REVIEWS

Adaptive immunity

(2010) Francisco A. Bonilla et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Personalized Medicine in Non–Small-Cell Lung Cancer: IsKRASa Useful Marker in Selecting Patients for Epidermal Growth Factor Receptor–Targeted Therapy?

(2010) Patrick J. Roberts et al.   JOURNAL OF CLINICAL ONCOLOGY

Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

(2009) K.-J. Rhee et al.   INFECTION AND IMMUNITY

Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre

(2009) Daniel Scharlau et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories

(2008) P.C.Y. Woo et al.   CLINICAL MICROBIOLOGY AND INFECTION

Wild-TypeBRAFIs Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer

(2008) Federica Di Nicolantonio et al.   JOURNAL OF CLINICAL ONCOLOGY

Mycoplasma infection transforms normal lung cells and induces bone morphogenetic protein 2 expression by post-transcriptional mechanisms

(2007) Shan Jiang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY