The Gut-Lung Axis in Health and Respiratory Diseases: A Place for Inter-Organ and Inter-Kingdom Crosstalks

Respiratory mycobiome and suggestion of inter-kingdom network during acute pulmonary exacerbation in cystic fibrosis

(2020) Perrine Soret et al.   Scientific Reports

A cellulolytic fungal biofilm enhances the consolidated bioconversion of cellulose to short chain fatty acids by the rumen microbiome

(2019) Charilaos Xiros et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Intestinal Inflammation in Children with Cystic Fibrosis Is Associated with Crohn’s-Like Microbiota Disturbances

(2019) Raphaël Enaud et al.   Journal of Clinical Medicine

Pseudomonas aeruginosa-Derived Volatile Sulfur Compounds Promote Distal Aspergillus fumigatus Growth and a Synergistic Pathogen-Pathogen Interaction That Increases Pathogenicity in Co-infection

(2019) Jennifer Scott et al.   Frontiers in Microbiology

The Lung Microbiota of Healthy Mice are Highly Variable, Cluster by Environment, and Reflect Variation in Baseline Lung Innate Immunity

(2018) Robert P. Dickson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

Antibiotic treatment–induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia

(2018) Oliver H. Robak et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut, microbiota-dependent trimethylamine- N -oxide is associated with long-term all-cause mortality in patients with exacerbated chronic obstructive pulmonary disease

(2018) Manuel Ottiger et al.   NUTRITION

Increased Small Intestinal Permeability during Severe Acute Exacerbations of COPD

(2018) Roy T.M. Sprooten et al.   RESPIRATION

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

(2018) Yuefeng Huang et al.   SCIENCE

Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations

(2018) David Mayhew et al.   THORAX

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

(2018) Marcus Fulde et al.   NATURE

The Microbiome and Tuberculosis: Early Evidence for Cross Talk

(2018) Sivaranjani Namasivayam et al.   mBio

Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice

(2018) Joseph H. Skalski et al.   PLoS Pathogens

Diet, Microbiota and Gut-Lung Connection

(2018) Swadha Anand et al.   Frontiers in Microbiology

The establishment of resident memory B cells in the lung requires local antigen encounter

(2018) S. Rameeza Allie et al.   NATURE IMMUNOLOGY

Experimental evolution of a fungal pathogen into a gut symbiont

(2018) Gloria Hoi Wan Tso et al.   SCIENCE

Neonatal gut and respiratory microbiota: coordinated development through time and space

(2018) Alex Grier et al.   Microbiome

Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment

(2017) Juliana Durack et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome

(2017) Asger Sverrild et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Corticosteroid treatment is associated with increased filamentous fungal burden in allergic fungal disease

(2017) Marcin G. Fraczek et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting

(2017) Marie-Claire Arrieta et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effect of probiotics on respiratory, gastrointestinal and nutritional outcomes in patients with cystic fibrosis: A systematic review

(2017) Jacqueline L. Anderson et al.   Journal of Cystic Fibrosis

Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids

(2017) A Cait et al.   Mucosal Immunology

Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study

(2017) Zhang Wang et al.   THORAX

Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD

(2017) Alison J Dicker et al.   THORAX

The lower airway microbiota in early cystic fibrosis lung disease: a longitudinal analysis

(2017) Katherine B Frayman et al.   THORAX

The microbiota protects against respiratory infection via GM-CSF signaling

(2017) Rebecca L. Brown et al.   Nature Communications

16S rDNA analysis of the effect of fecal microbiota transplantation on pulmonary and intestinal flora

(2017) Tianhao Liu et al.   3 Biotech

Protective Microbiota: From Localized to Long-Reaching Co-Immunity

(2017) Lynn Chiu et al.   Frontiers in Immunology

The gut mycobiome of the Human Microbiome Project healthy cohort

(2017) Andrea K. Nash et al.   Microbiome

16S rDNA analysis of the effect of fecal microbiota transplantation on pulmonary and intestinal flora

(2017) Tianhao Liu et al.   3 Biotech

Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer

(2017) Rea Bingula et al.   Journal of Oncology

Effects of Propidium Monoazide (PMA) Treatment on Mycobiome and Bacteriome Analysis of Cystic Fibrosis Airways during Exacerbation

(2017) Linh Do Ngoc Nguyen et al.   PLoS One

Immunological Consequences of Intestinal Fungal Dysbiosis

(2016) Matthew L. Wheeler et al.   Cell Host & Microbe

Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma

(2016) L. T. Stiemsma et al.   CLINICAL SCIENCE

Lung microbiome dynamics in COPD exacerbations

(2016) Zhang Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways

(2016) Darcy R. Denner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome

(2016) Jeremy P. McAleer et al.   JOURNAL OF IMMUNOLOGY

Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes

(2016) Qingling Zhang et al.   PLoS One

Disrupted progression of the intestinal microbiota with age in children with cystic fibrosis

(2016) Shaun Nielsen et al.   Scientific Reports

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome

(2016) Robert P. Dickson et al.   Nature Microbiology

Microbiological profiles of sputum and gastric juice aspirates in Cystic Fibrosis patients

(2016) H. Al-momani et al.   Scientific Reports

Production of short-chain fatty acids from the biodegradation of wheat straw lignin by Aspergillus fumigatus

(2015) Eduardo Baltierra-Trejo et al.   BIORESOURCE TECHNOLOGY

Shaping the oral mycobiota: interactions of opportunistic fungi with oral bacteria and the host

(2015) H Xu et al.   CURRENT OPINION IN MICROBIOLOGY

Influence and effect of the human microbiome in allergy and asthma

(2015) Ariane R. Panzer et al.   CURRENT OPINION IN RHEUMATOLOGY

Host-Microbiota Interactions in the Intestine

(2015) Charles O. Elson et al.   DIGESTIVE DISEASES

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia

(2015) Stefanie Gauguet et al.   INFECTION AND IMMUNITY

The airway microbiome in patients with severe asthma: Associations with disease features and severity

(2015) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis

(2015) Anne G. Hoen et al.   JOURNAL OF PEDIATRICS

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Alternate Healthy Eating Index 2010 and risk of chronic obstructive pulmonary disease among US women and men: prospective study

(2015) R. Varraso et al.   BMJ-British Medical Journal

Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation

(2015) Sang Hu Kim et al.   PLoS Pathogens

Alternate Healthy Eating Index 2010 and risk of chronic obstructive pulmonary disease among US women and men: prospective study

(2015) R. Varraso et al.   BMJ-British Medical Journal

The lung mycobiome: an emerging field of the human respiratory microbiome

(2015) Linh D. N. Nguyen et al.   Frontiers in Microbiology

Lung microbiota across age and disease stage in cystic fibrosis

(2015) Bryan Coburn et al.   Scientific Reports

Gut Dysbiosis Promotes M2 Macrophage Polarization and Allergic Airway Inflammation via Fungi-Induced PGE2

(2014) Yun-Gi Kim et al.   Cell Host & Microbe

Prenatal and post-natal exposure to antibiotics and risk of asthma in childhood

(2014) J. Metsälä et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Nasal and Sinus Microbiome in Health and Disease

(2014) Michael T. Wilson et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient over a Multiyear Period

(2014) Joshua R. Stokell et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Severity-Related Changes of Bronchial Microbiome in Chronic Obstructive Pulmonary Disease

(2014) M. Garcia-Nunez et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

(2014) Jian Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microbiota-Derived Compounds Drive Steady-State Granulopoiesis via MyD88/TICAM Signaling

(2014) Maria L. Balmer et al.   JOURNAL OF IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

(2014) Eva S Gollwitzer et al.   NATURE MEDICINE

Potentially Pathogenic Airway Bacteria and Neutrophilic Inflammation in Treatment Resistant Severe Asthma

(2014) Benjamin J. Green et al.   PLoS One

Changes in the Bacterial Microbiota in Gut, Blood, and Lungs following Acute LPS Instillation into Mice Lungs

(2014) Marc A. Sze et al.   PLoS One

The Microbial Community of the Cystic Fibrosis Airway Is Disrupted in Early Life

(2014) Julie Renwick et al.   PLoS One

The microbiome in pediatric cystic fibrosis patients: the role of shared environment suggests a window of intervention

(2014) Thomas H Hampton et al.   Microbiome

Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis

(2014) Sven D Willger et al.   Microbiome

Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease

(2013) Philip L. Molyneaux et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Differences in fungi present in induced sputum samples from asthma patients and non-atopic controls: a community based case control study

(2013) Hugo Cornelis van Woerden et al.   BMC INFECTIOUS DISEASES

Streptococcal co-infection augmentsCandidapathogenicity by amplifying the mucosal inflammatory response

(2013) H. Xu et al.   CELLULAR MICROBIOLOGY

Low gut microbiota diversity in early infancy precedes asthma at school age

(2013) T. R. Abrahamsson et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Escherichia coli Dysbiosis Correlates With Gastrointestinal Dysfunction in Children With Cystic Fibrosis

(2013) Lucas R. Hoffman et al.   CLINICAL INFECTIOUS DISEASES

Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response

(2013) Dipti Karmarkar et al.   IMMUNOLOGY

Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract

(2013) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Archaea and Fungi of the Human Gut Microbiome: Correlations with Diet and Bacterial Residents

(2013) Christian Hoffmann et al.   PLoS One

The emerging world of the fungal microbiome

(2013) Gary B. Huffnagle et al.   TRENDS IN MICROBIOLOGY

The Lung Tissue Microbiome in Chronic Obstructive Pulmonary Disease

(2012) Marc A. Sze et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effect of dietary β-glucan on growth performance, fecal microbial shedding and immunological responses after lipopolysaccharide challenge in weaned pigs

(2012) T.X. Zhou et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma

(2012) Shannon L Russell et al.   EMBO REPORTS

Comparative analysis of the distribution of segmented filamentous bacteria in humans, mice and chickens

(2012) Yeshi Yin et al.   ISME Journal

Asthma-associated differences in microbial composition of induced sputum

(2012) Pradeep Reddy Marri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

(2012) Laurence Delhaes et al.   PLoS One

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Endogenous Bacteria Alter Gut Epithelial Apoptosis and Decrease Mortality Following Pseudomonas aeruginosa Pneumonia

(2012) Amy C. Fox et al.   SHOCK

Serial Analysis of the Gut and Respiratory Microbiome in Cystic Fibrosis in Infancy: Interaction between Intestinal and Respiratory Tracts and Impact of Nutritional Exposures

(2012) J. C. Madan et al.   mBio

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

(2011) Tina Herbst et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Synergistic Interaction between Candida albicans and Commensal Oral Streptococci in a NovelIn VitroMucosal Model

(2011) Patricia I. Diaz et al.   INFECTION AND IMMUNITY

Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy

(2011) Frederika A. van Nimwegen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Low diversity of the gut microbiota in infants with atopic eczema

(2011) Thomas R. Abrahamsson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transient TLR Activation Restores Inflammatory Response and Ability To Control Pulmonary Bacterial Infection in Germfree Mice

(2011) C. T. Fagundes et al.   JOURNAL OF IMMUNOLOGY

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Medically important bacterial–fungal interactions

(2010) Anton Y. Peleg et al.   NATURE REVIEWS MICROBIOLOGY

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Disordered Microbial Communities in Asthmatic Airways

(2010) Markus Hilty et al.   PLoS One

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

(2010) Michael J. Cox et al.   PLoS One

Antibiotic-resistant obligate anaerobes during exacerbations of cystic fibrosis patients

(2009) D. Worlitzsch et al.   CLINICAL MICROBIOLOGY AND INFECTION

Genetic Analysis of the Role of Peroxisomes in the Utilization of Acetate and Fatty Acids in Aspergillus nidulans

(2008) M. J. Hynes et al.   GENETICS

Early intestinal Bacteroides fragilis colonisation and development of asthma

(2008) Carl Vael et al.   BMC Pulmonary Medicine