Lung carcinogenesis by tobacco smoke

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers

(2012) J.-M. Yuan et al.   CARCINOGENESIS

Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC

(2011) M. N. Timofeeva et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Nicotine Does Not Enhance Tumorigenesis in Mutant K-Ras-Driven Mouse Models of Lung Cancer

(2011) C. R. Maier et al.   Cancer Prevention Research

Chronic Nicotine Consumption Does Not Influence 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Tumorigenesis

(2011) S. E. Murphy et al.   Cancer Prevention Research

Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers

(2011) J.-M. Yuan et al.   CANCER RESEARCH

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice

(2011) M.Christine Hollander et al.   CARCINOGENESIS

Relationship Between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 Variation and Smoking Behaviors and Lung Cancer Risk

(2011) Catherine A. Wassenaar et al.   JNCI-Journal of the National Cancer Institute

Lung Cancer Risk Prediction: Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Models and Validation

(2011) C. Martin Tammemagi et al.   JNCI-Journal of the National Cancer Institute

Smoking-related O4-ethylthymidine formation in human lung tissue and comparisons with bulky DNA adducts

(2011) L. Anna et al.   MUTAGENESIS

Association of the CHRNA5-A3-B4 Gene Cluster With Heaviness of Smoking: A Meta-Analysis

(2011) Jennifer J. Ware et al.   NICOTINE & TOBACCO RESEARCH

Research Opportunities Related to Establishing Standards for Tobacco Products Under the Family Smoking Prevention and Tobacco Control Act

(2011) S. S. Hecht   NICOTINE & TOBACCO RESEARCH

Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk

(2011) Yufei Wang et al.   PLoS One

Estimating Individual Risk for Lung Cancer

(2011) Carol Etzel et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetic Effects and Molecular Mechanisms of Tumorigenesis Induced by Cigarette Smoke: An Overview

(2011) Rong-Jane Chen et al.   Journal of Oncology

Tobacco Smoke Promotes Lung Tumorigenesis by Triggering IKKβ- and JNK1-Dependent Inflammation

(2010) Hiroyuki Takahashi et al.   CANCER CELL

Analysis of Phenanthrene and Benzo[a]pyrene Tetraol Enantiomers in Human Urine: Relevance to the Bay Region Diol Epoxide Hypothesis of Benzo[a]pyrene Carcinogenesis and to Biomarker Studies

(2010) Stephen S. Hecht et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Applying Tobacco Carcinogen and Toxicant Biomarkers in Product Regulation and Cancer Prevention

(2010) Stephen S. Hecht et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Detection of Lipid Peroxidation-Induced DNA Adducts Caused by 4-Oxo-2(E)-nonenal and 4-Oxo-2(E)-hexenal in Human Autopsy Tissues

(2010) Pei-Hsin Chou et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Analysis of Acrolein-Derived 1,N2-Propanodeoxyguanosine Adducts in Human Leukocyte DNA from Smokers and Nonsmokers

(2010) Siyi Zhang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model

(2010) Jill E. Kucab et al.   FEBS Journal

The mutation spectrum revealed by paired genome sequences from a lung cancer patient

(2010) William Lee et al.   NATURE

Murine lung tumor response after exposure to cigarette mainstream smoke or its particulate and gas/vapor phase fractions

(2010) Walter Stinn et al.   TOXICOLOGY

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

(2010) Nancy L. Saccone et al.   PLoS Genetics

A Prospectively Measured Serum Biomarker for a Tobacco-Specific Carcinogen and Lung Cancer in Smokers

(2009) T. R. Church et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Strain-dependent differences in susceptibility to lung cancer in inbred mice exposed to mainstream cigarette smoke

(2009) Terry Gordon et al.   CANCER LETTERS

Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers

(2009) J.-M. Yuan et al.   CANCER RESEARCH

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Mutational spectra of human cancer

(2009) Gerd P. Pfeifer et al.   HUMAN GENETICS

Nicotine Dependence Pharmacogenetics: Role of Genetic Variation in Nicotine-Metabolizing Enzymes

(2009) Riju Ray et al.   JOURNAL OF NEUROGENETICS

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

Pharmacology of Nicotine: Addiction, Smoking-Induced Disease, and Therapeutics

(2008) Neal L. Benowitz   Annual Review of Pharmacology and Toxicology

Development and Validation of a Lung Cancer Risk Prediction Model for African-Americans

(2008) C. J. Etzel et al.   Cancer Prevention Research

An Expanded Risk Prediction Model for Lung Cancer

(2008) M. R. Spitz et al.   Cancer Prevention Research

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

Inflammation in lung carcinogenesis: New targets for lung cancer chemoprevention and treatment

(2008) Jay M. Lee et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

Progress and Challenges in Selected Areas of Tobacco Carcinogenesis

(2007) Stephen S. Hecht   CHEMICAL RESEARCH IN TOXICOLOGY