Plasmacytoid Dendritic Cells, a Novel Target in Myeloid Neoplasms

Chronic myelomonocytic leukemia: 2022 update on diagnosis, risk stratification, and management

(2022) Mrinal M. Patnaik et al.   AMERICAN JOURNAL OF HEMATOLOGY

Myeloid neoplasms and clonal hematopoiesis from the RUNX1 perspective

(2022) Yoshihiro Hayashi et al.   LEUKEMIA

Role of the bone marrow immune microenvironment in chronic myelomonocytic leukemia pathogenesis: novel mechanisms and insights into clonal propagation

(2022) Abhishek A. Mangaonkar et al.   LEUKEMIA & LYMPHOMA

CD123 and More: How to Target the Cell Surface of Blastic Plasmacytoid Dendritic Cell Neoplasm

(2022) Elodie Bôle-Richard et al.   Cancers

Leukemia vaccine overcomes limitations of checkpoint blockade by evoking clonal T cell responses in a murine acute myeloid leukemia model

(2021) Dina Stroopinsky et al.   HAEMATOLOGICA

Reduced frequencies and functional impairment of dendritic cell subsets and non-classical monocytes in myelodysplastic syndromes

(2021) Nathalie Van Leeuwen-Kerkhoff et al.   HAEMATOLOGICA

Chronic myelomonocytic leukemia diagnosis and management

(2021) Onyee Chan et al.   LEUKEMIA

Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0

(2021) Yvonne Grobben et al.   Frontiers in Immunology

Investigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review

(2021) Georgia Wells et al.   Frontiers in Immunology

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

(2021) Florian Renosi et al.   Blood Advances

Achieving clinical success with BET inhibitors as anti-cancer agents

(2021) Tatiana Shorstova et al.   BRITISH JOURNAL OF CANCER

Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes

(2021) Grégory Ehx et al.   IMMUNITY

T-cell-based immunotherapy of acute myeloid leukemia: current concepts and future developments

(2021) Naval Daver et al.   LEUKEMIA

Allogeneic stem cell transplantation for AML patients with RUNX1 mutation in first complete remission: a study on behalf of the acute leukemia working party of the EBMT

(2021) Johanna Waidhauser et al.   BONE MARROW TRANSPLANTATION

Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS

(2021) Jennifer J. Trowbridge et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets

(2021) Matthew R. Hass et al.   PLoS Genetics

Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma

(2021) Yousef Zakharia et al.   Journal for ImmunoTherapy of Cancer

Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2

(2021) Christopher P. Mill et al.   BLOOD

Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation

(2021) Xiaona You et al.   BLOOD

Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy

(2021) Hussein A. Abbas et al.   Nature Communications

The Role of Plasmacytoid Dendritic Cells in Cancers

(2021) Binhui Zhou et al.   Frontiers in Immunology

Immune landscape in vulvar cancer-draining lymph nodes indicates distinct immune escape mechanisms in support of metastatic spread and growth

(2021) Anne Marijne Heeren et al.   Journal for ImmunoTherapy of Cancer

CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm

(2020) Elodie Bôle-Richard et al.   LEUKEMIA

T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies

(2020) Valérie Janelle et al.   Frontiers in Immunology

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies

(2020) Mark P. Chao et al.   Frontiers in Oncology

OX40+ plasmacytoid dendritic cells in the tumor microenvironment promote antitumor immunity

(2020) Kate Poropatich et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune escape and immunotherapy of acute myeloid leukemia

(2020) Luca Vago et al.   JOURNAL OF CLINICAL INVESTIGATION

Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs

(2020) Tomoya Muto et al.   NATURE IMMUNOLOGY

Transcriptional Networks Driving Dendritic Cell Differentiation and Function

(2020) Stephen L. Nutt et al.   IMMUNITY

Characterization of a Novel FLT3 BiTE® Antibody Construct for the Treatment of Acute Myeloid Leukemia

(2020) Bettina Brauchle et al.   MOLECULAR CANCER THERAPEUTICS

Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1

(2020) Erik L. Brincks et al.   Oncotarget

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia

(2020) Wenbin Xiao et al.   BLOOD

Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape

(2020) Loria Zalmaï et al.   HAEMATOLOGICA

Novel concepts in plasmacytoid dendritic cell (pDC) development and differentiation

(2020) Patrick Fernandes Rodrigues et al.   MOLECULAR IMMUNOLOGY

Plasmacytoid dendritic cells cross-prime naive CD8 T cells by transferring antigen to conventional dendritic cells through exosomes

(2020) Chunmei Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients

(2020) Matthew S. Block et al.   Nature Communications

IDO Expression in Cancer: Different Compartment, Different Functionality?

(2020) Annabel Meireson et al.   Frontiers in Immunology

TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals

(2020) Francesco Manfredi et al.   Frontiers in Immunology

Acute Myeloid Leukemia: From Biology to Clinical Practices Through Development and Pre-Clinical Therapeutics

(2020) Xavier Roussel et al.   Frontiers in Oncology

Flow Cytometry Identifies a Spectrum of Maturation in Myeloid Neoplasms Having Plasmacytoid Dendritic Cell Differentiation

(2019) Fatima Hamadeh et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Plasmacytoid Dendritic Cells: Development, Regulation, and Function

(2019) Boris Reizis   IMMUNITY

Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma

(2019) Rocky M. Barilla et al.   Nature Communications

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

(2019) Nolwenn Lucas et al.   LEUKEMIA

RUNX1 targeted therapy for AML expressing somatic or germline mutation in RUNX1

(2019) Christopher P Mill et al.   BLOOD

Acute myeloid leukaemia niche regulates response to L‐asparaginase

(2019) Ilaria M. Michelozzi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm

(2019) Naveen Pemmaraju et al.   NEW ENGLAND JOURNAL OF MEDICINE

Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects

(2019) Maria Rosaria Sapienza et al.   Cancers

Costimulatory Molecules and Immune Checkpoints Are Differentially Expressed on Different Subsets of Dendritic Cells

(2019) Claudia Carenza et al.   Frontiers in Immunology

Dendritic Cell Metabolism and Function in Tumors

(2019) Paolo Giovanelli et al.   TRENDS IN IMMUNOLOGY

CD123 as a Therapeutic Target in the Treatment of Hematological Malignancies

(2019) Testa et al.   Cancers

Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes

(2019) Guillermo Montalban-Bravo et al.   LEUKEMIA

Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia

(2019) Anupriya Agarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid Neoplasms with Elevated Plasmacytoid Dendritic Cell Differentiation Reflect the Maturation Process of Dendritic Cells

(2019) Yumei Huang et al.   CYTOMETRY PART A

Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population

(2019) Rebecca Leylek et al.   Cell Reports

Genetic compensation of RUNX family transcription factors in leukemia

(2018) Yasuhiko Kamikubo   CANCER SCIENCE

Immune regulation by CD8+ Treg cells: novel possibilities for anticancer immunotherapy

(2018) Shuping Zhang et al.   Cellular & Molecular Immunology

The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

(2018) Tuo Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

(2018) Takanori Komada et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ikaros cooperates with Notch activation and antagonizes TGFβ signaling to promote pDC development

(2018) Jérôme Mastio et al.   PLoS Genetics

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

(2018) Liru Wang et al.   OncoImmunology

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

(2018) Yixiang Han et al.   Frontiers in Immunology

The distribution of T-cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia

(2018) Patrick Williams et al.   CANCER

Kinetics of adult hematopoietic stem cell differentiation in vivo

(2018) Samik Upadhaya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy

(2018) Mandy van Gulijk et al.   Frontiers in Immunology

Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm

(2017) Laure Philippe et al.   HAEMATOLOGICA

Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification

(2017) Lucja T. Grajkowska et al.   IMMUNITY

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization

(2017) Marcela Alcántara-Hernández et al.   IMMUNITY

Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs

(2017) Shixin Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death

(2017) Bridget Larkin et al.   JOURNAL OF IMMUNOLOGY

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm

(2017) Laure Philippe et al.   HAEMATOLOGICA

GITR ligand fusion protein agonist enhances the tumor antigen–specific CD8 T-cell response and leads to long-lasting memory

(2017) Nick M. Durham et al.   Journal for ImmunoTherapy of Cancer

Acute lymphoblastic leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2016) D. Hoelzer et al.   ANNALS OF ONCOLOGY

LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis

(2016) A. Ceroi et al.   BLOOD

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

(2016) Hartmut Döhner et al.   BLOOD

Integrating clinical features and genetic lesions in the risk assessment of patients with chronic myelomonocytic leukemia

(2016) C. Elena et al.   BLOOD

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm

(2016) Michele Ceribelli et al.   CANCER CELL

Dendritic Cell-Based Immunotherapy: State of the Art and Beyond

(2016) K. F. Bol et al.   CLINICAL CANCER RESEARCH

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively

(2016) Dorine Sichien et al.   IMMUNITY

Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function

(2016) Duojiao Wu et al.   IMMUNITY

ICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated withHelicobacter pylori

(2016) Hirotsugu Nagase et al.   INTERNATIONAL JOURNAL OF CANCER

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

(2016) Charlotte L. Scott et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NFATC3 promotes IRF7 transcriptional activity in plasmacy­­toid dendritic cells

(2016) Musheng Bao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional Repression of IFN Regulatory Factor 7 by MYC Is Critical for Type I IFN Production in Human Plasmacytoid Dendritic Cells

(2016) Tae Whan Kim et al.   JOURNAL OF IMMUNOLOGY

BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells

(2016) D T Saenz et al.   LEUKEMIA

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

(2016) V I Gaidzik et al.   LEUKEMIA

Transcription factor Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate

(2016) Xiaodi Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax

(2016) Joan Montero et al.   Cancer Discovery

Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response

(2016) Tiejun Li et al.   Scientific Reports

Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan

(2016) Yifan Zhan et al.   Scientific Reports

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity

(2016) Michaël Chopin et al.   Cell Reports

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study

(2016) Céline Berthon et al.   Lancet Haematology

Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells

(2015) Xiongwei Cai et al.   Cell Stem Cell

Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment

(2015) Shuping Zhang et al.   Cellular & Molecular Immunology

Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes

(2015) I Gañán-Gómez et al.   LEUKEMIA

Dendritic cells require NIK for CD40-dependent cross-priming of CD8+T cells

(2015) Anand K. Katakam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ag-Presenting CpG-Activated pDCs Prime Th17 Cells That Induce Tumor Regression

(2014) L. Guery et al.   CANCER RESEARCH

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

(2014) Seng-Ryong Woo et al.   IMMUNITY

ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2

(2014) Hiyaa S. Ghosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition

(2014) M R Sapienza et al.   LEUKEMIA

Dendritic cell fate is determined by BCL11A

(2014) G. C. Ippolito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation-driven carcinogenesis is mediated through STING

(2014) Jeonghyun Ahn et al.   Nature Communications

Deletion of the NF- B subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function

(2013) S. J. Stein et al.   BLOOD

A Clonogenic Progenitor with Prominent Plasmacytoid Dendritic Cell Developmental Potential

(2013) Nobuyuki Onai et al.   IMMUNITY

Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2

(2013) K. Yasuda et al.   INTERNATIONAL IMMUNOLOGY

Breast cancer-derived transforming growth factor-β and tumor necrosis factor-α compromise interferon-α production by tumor-associated plasmacytoid dendritic cells

(2013) Vanja Sisirak et al.   INTERNATIONAL JOURNAL OF CANCER

Transcription factor Runx2 controls the development and migration of plasmacytoid dendritic cells

(2013) Catherine M. Sawai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A type I IFN–Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors

(2013) Yi-Ling Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents

(2013) H Yang et al.   LEUKEMIA

Metabolites of tryptophan catabolism are elevated in sera of patients with myelodysplastic syndromes and inhibit hematopoietic progenitor amplification

(2013) Céline Berthon et al.   LEUKEMIA RESEARCH

Bcl11a Controls Flt3 Expression in Early Hematopoietic Progenitors and Is Required for pDC Development In Vivo

(2013) Xiaodi Wu et al.   PLoS One

ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+T cells by plasmacytoid dendritic cells

(2013) Julien Faget et al.   OncoImmunology

Spi-B is critical for plasmacytoid dendritic cell function and development

(2012) I. Sasaki et al.   BLOOD

Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells

(2012) P. Sathe et al.   BLOOD

Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3+ T-Regulatory Cells

(2012) C. Conrad et al.   CANCER RESEARCH

Runx1 Deficiency in CD4+ T Cells Causes Fatal Autoimmune Inflammatory Lung Disease Due to Spontaneous Hyperactivation of Cells

(2012) W. F. Wong et al.   JOURNAL OF IMMUNOLOGY

Bone marrow dendritic cells are reduced in patients with high-risk myelodysplastic syndromes

(2012) Leonie Saft et al.   LEUKEMIA RESEARCH

Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis

(2012) Sana Intidhar Labidi-Galy et al.   OncoImmunology

RUNX1 Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group

(2011) Verena I. Gaidzik et al.   JOURNAL OF CLINICAL ONCOLOGY

RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis

(2010) S. Schnittger et al.   BLOOD

Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia

(2010) S. M. Kornblau et al.   BLOOD

Expression of Toll-like receptor 9 in bone marrow cells of myelodysplastic syndromes is down-regulated during transformation to overt leukemia

(2010) Nobuo Kuninaka et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells

(2010) A. Curti et al.   HAEMATOLOGICA

Mammalian Target of Rapamycin Controls Dendritic Cell Development Downstream of Flt3 Ligand Signaling

(2010) Taheri Sathaliyawala et al.   IMMUNITY

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

Cutaneous Manifestations of Blastic Plasmacytoid Dendritic Cell Neoplasm—Morphologic and Phenotypic Variability in a Series of 33 Patients

(2009) Carlo Cota et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia

(2009) N. Droin et al.   BLOOD

IL-17-producing CD4+T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome

(2009) Shahram Y. Kordasti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells

(2009) Akihiko Kitoh et al.   IMMUNITY

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

(2009) B. Baban et al.   JOURNAL OF IMMUNOLOGY

Immunophenotypical, morphologic, and functional characterization of maturation-associated plasmacytoid dendritic cell subsets in normal adult human bone marrow

(2009) Lourdes Martín-Martín et al.   TRANSFUSION

The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes

(2008) Apostolia Maria Tsimberidou et al.   CANCER

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B

(2008) Maho Nagasawa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8

(2008) Eiji Esashi et al.   IMMUNITY