Investigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review

Identification of novel serum biomarker for the detection of acute myeloid leukemia based on liquid chromatography-mass spectrometry

(2019) Dong Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Limitations and Off-Target Effects of Tryptophan-Related IDO Inhibitors in Cancer Treatment

(2019) Juliane Günther et al.   Frontiers in Immunology

Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study

(2019) Georgina V Long et al.   LANCET ONCOLOGY

Indoleamine 2,3-Dioxygenase (IDO) Inhibition as a Strategy to Augment Cancer Immunotherapy

(2018) Sarah Yentz et al.   BIODRUGS

Clinical and biological implications of mutational spectrum in acute myeloid leukemia of FAB subtypes M4 and M5

(2018) Zhiheng Cheng et al.   CANCER GENE THERAPY

New and emerging therapies for acute myeloid leukaemia

(2018) Julian R Davis et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Immune checkpoint inhibitors in cancer therapy: a focus on T-regulatory cells

(2017) Varun Sasidharan Nair et al.   IMMUNOLOGY AND CELL BIOLOGY

Acute Myeloid Leukaemia: New Targets and Therapies

(2017) Geoffrey Brown et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FLT3 Inhibitors in Acute Myeloid Leukemia: Current Status and Future Directions

(2017) Maria Larrosa-Garcia et al.   MOLECULAR CANCER THERAPEUTICS

ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells

(2017) Mariangela Lecciso et al.   Frontiers in Immunology

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

(2017) Abhishek Mangaonkar et al.   Scientific Reports

Harnessing the immune system in acute myeloid leukaemia

(2016) Rebecca Austin et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Indoleamine 2,3-dioxygenase and regulatory T cells in acute myeloid leukemia

(2016) Iman Mansour et al.   Hematology

Prognostic value of the combination of seruml-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia

(2016) Takeshi Hara et al.   LEUKEMIA & LYMPHOMA

TIM-3/Gal-9 interaction induces IFNγ-dependent IDO1 expression in acute myeloid leukemia blast cells

(2015) Valentina Folgiero et al.   Journal of Hematology & Oncology

High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia

(2015) Ryoko Mabuchi et al.   LEUKEMIA & LYMPHOMA

PGE2-Induced IDO1 Inhibits the Capacity of Fully Mature DCs to Elicit anIn VitroAntileukemic Immune Response

(2015) Sara Trabanelli et al.   Journal of Immunology Research

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia

(2015) Valentina Folgiero et al.   Oncotarget

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

(2014) Richard Metz et al.   INTERNATIONAL IMMUNOLOGY

Expression of indoleamine 2,3-dioxygenase in leukemic cells indicates an unfavorable prognosis in acute myeloid leukemia patients with intermediate-risk cytogenetics

(2014) Kenji Fukuno et al.   LEUKEMIA & LYMPHOMA

Indoleamine 2,3 dioxygenase contributes to transferable tolerance in rat red blood cell inducible model of experimental autoimmune haemolytic anaemia

(2013) L. N. Dahal et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4

(2013) Rikke B. Holmgaard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Acute myeloid leukaemia in adults

(2013) Felicetto Ferrara et al.   LANCET

Cyclooxygenase-2 (COX-2) Inhibition Constrains Indoleamine 2,3-Dioxygenase 1 (IDO1) Activity in Acute Myeloid Leukaemia Cells

(2013) Maria Iachininoto et al.   MOLECULES

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

T-Regulatory Cells: Key Players in Tumor Immune Escape and Angiogenesis

(2012) A. Facciabene et al.   CANCER RESEARCH

Indoleamine 2,3-dioxygenase: From catalyst to signaling function

(2012) Francesca Fallarino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+CD25+CD127low/− T Cells: A More Specific Treg Population in Human Peripheral Blood

(2012) Ning Yu et al.   INFLAMMATION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

FLT3 inhibition as a targeted therapy for acute myeloid leukemia

(2010) Miguel Sanz et al.   CURRENT OPINION IN ONCOLOGY

Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells

(2010) A. Curti et al.   HAEMATOLOGICA

Involvement of Oxidative Stress in the Relapse of Acute Myeloid Leukemia

(2010) Fu-Ling Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells

(2010) Noura M. El Kholy et al.   MEDICAL ONCOLOGY

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

High INDO (indoleamine 2,3-dioxygenase) mRNA level in blasts of acute myeloid leukemic patients predicts poor clinical outcome

(2008) M. E.D. Chamuleau et al.   HAEMATOLOGICA

Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients’ sera by HPLC and is inducible by IFN-γ

(2008) Selim Corm et al.   LEUKEMIA RESEARCH

Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: Absence of toxicity due to saturating absorption

(2007) Lee Jia et al.   FOOD AND CHEMICAL TOXICOLOGY